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LATS1: large tumor suppressor kinase 1
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Gene · 9113

Papers3,081

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 3,081

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TitleJournalYearPMIDFound bySource
Melatonin ameliorates diabetic retinopathy by inhibiting PANoptosis via the LncSNHG5/miR-26a-5p/Hippo signaling axis.J Pharmacol Sci202642810779PubTator, text miningPubMed
Down-regulation of RhoA inhibits YAP by activating Hippo signaling to promote macrophage M1 polarization and enhance its phagocytosis, thereby inhibiting AML progression in preclinical models.Mol Cell Probes202642790655PubTator, text miningPubMed
Identification of candidate variants in plasma associated with early versus late disease progression under anti-PD-1 therapy in metastatic NSCLC.Transl Lung Cancer Res202642723788PubTator, text miningPubMed
Upstream Regulation of the Hippo Pathway.Cold Spring Harb Perspect Biol202642697693PubTator, text miningPubMed
Epitranscriptomic silencing of STK25 promotes ferroptosis evasion via the METTL3-YAP-GPX4 axis in osteosarcoma.Cancer Lett202642679917PubTator, text miningPubMed
LATS1/2 inactivation drives a distinct venous endothelial cell response that contributes to fibrotic remodeling of the lung.Sci Adv202642664350PubTator, text miningPubMed
Yorkie/YAP Interactors: Fine-Tuning the Hippo Pathway Output.Cold Spring Harb Perspect Biol202642575696PubTator, text miningPubMed
LINC00673-V4 Promotes Colorectal Cancer Cell Proliferation by Interacting With FUS and Restoring the Expression of Hippo-YAP Target Genes.Front Biosci (Landmark Ed)202642530263PubTator, text miningPubMed
Alteration in the Yap Signaling Pathway in Cataractous Human Lens Epithelium.Curr Eye Res202642494054PubTator, text miningPubMed
Targeting Sirtuins in Thyroid Cancer: Mechanisms, Drug Development, and Emerging Roles in Tumor Immunity and Ferroptosis.Cancers (Basel)202642449637PubTator, text miningPubMed
miR-6836-5p Drives Astrocyte Pro-survival Signaling Through DLG2-Hippo-YAP Pathway Under AQP4-IgG + ve NMOSD Stress.Mol Neurobiol202642399450PubTator, text miningPubMed
High glucose-induced mitochondrial fission promotes Müller cell activation via suppression of the Hippo pathway.Mol Cell Biochem202642397510PubTator, text miningPubMed
Repurposing salmon calcitonin for glioblastoma treatment: Targeting Yes-associated Protein (YAP)/ Transcriptional co‑activator with PDZ‑binding motif (TAZ) via hippo pathway activation.Neurooncol Adv202642394646PubTator, text miningPubMed
A human iPSC model with LATS1/2 knockdown (MUSIi012-A-9) for investigating Hippo signaling in stem cell.Stem Cell Res202642378908PubTator, text miningPubMed
aPKC-ζ III promotes trophoblast fusion by altering Par-3 interactions with Hippo signaling kinase LATS1.Stem Cell Reports202642349426PubTator, text miningPubMed
Polarity protein MALS3 suppresses breast cancer stem cell-like properties by promoting TAZ inactivation and ubiquitination-dependent degradation.Cell Death Dis202642323314PubTator, text miningPubMed
TEAD1 condensates are transcriptionally inactive storage sites on the pericentromeric heterochromatin in cancer cells.Nat Cell Biol202642277434PubTator, text miningPubMed
Epigenetic silencing of TBX1 inactivates the Hippo pathway to potentiate chemoresistance in esophageal squamous cell carcinoma.Cell Death Dis202642265086PubTator, text miningPubMed
NEDD8 Promotes the Progression and Inflammation of Keratoconus by Increasing the Expression of YAP1.Invest Ophthalmol Vis Sci202642262027PubTator, text miningPubMed
Solamargine alleviates liver fibrosis by regulating YAP signaling in hepatic stellate cells.Zhong Nan Da Xue Xue Bao Yi Xue Ban202642244286PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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