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Gene · 9118

INA: internexin neuronal intermediate filament protein alpha

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. INA: internexin neuronal intermediate filament protein alpha. Genes, record 9118. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9118

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Gene

Symbol
INA
HGNC
Name
internexin neuronal intermediate filament protein alpha
HGNC
NCBI Gene ID
9118
NCBI Gene
HGNC ID
HGNC:6057
HGNC
Ensembl
ENSG00000148798
NCBI Gene
Aliases
NEF5, NF-66, NF66, TXBP-1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q16352Alpha-internexin4990Ensembl, GeneID, HGNC

Source UniProt

Patents31

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-298868Q16352Espacenet
JP 2025517969 A2025-06-128868Q16352Espacenet
JP 2024096258 A2024-07-126Q16352Espacenet
JP 2023118821 A2023-08-257Q16352Espacenet
US 11564998 B22023-01-316232Q16352Espacenet
US 11474113 B22022-10-187Q16352Espacenet
US 11446398 B22022-09-2041741Q16352Espacenet
JP 2022524081 A2022-04-27144712Q16352Espacenet
JP 2022513721 A2022-02-0912Q16352Espacenet
KR 1020210102294 A2021-08-196Q16352Espacenet

1 to 10 of 31

See all 31 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,432

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleINA papersNewest fiscal year
R01HL131517Sex-specific arrhythmogenic mechanisms of atrial fibrillation102025
P30CA008748Cancer Center Support Grant62025
R01HL135109Targeting the Arrhythmogenic Sources of Human Atrial Fibrillation62025
R01HL141214Functional Microdomains in the Heart's Pacemaker: A New Dimension of Cardiac Remodeling42025
R01NS082351Understanding the Cellular Basis of Movement Disorders42025
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions32025
P01HL141084Multiscale Systems to Elucidate Susceptibility and Cardioprotective Mechanisms in Cardio-oncology32025
P30CA016086Cancer Center Support Grant32025
P30CA068485Cancer Center Support Grant32025
P30DK058404Molecular and Cellular Basis for Digestive Diseases32025

1 to 10 of 1,432Source NIH's project files

See all 1,432 nih grants

Papers2,019

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Floral KNOX Expression Supports Parallel Evolution of Nectar Spurs in Snapdragon Relatives (Antirrhineae: Plantaginaceae).Evol Dev202642733969PubTator, text miningPubMed
Positive neonatal direct antiglobulin test and free circulating panagglutinin due to high-titer immunoglobulin G1 anti-Inb without in vivo hemolysis.Transfusion202642671039PubTator, text miningPubMed
Evaluation of the impact of deltamethrin, dapagliflozin, and KB-R7943 on INa in HL-1 atrial myocytes and U2OS osteosarcoma cells: An investigative study.Environ Toxicol Pharmacol202642624342PubTator, text miningPubMed
Pharmacological Insights and Clinical Challenges of Wenxin Keli in Arrhythmia Treatment.Anatol J Cardiol202642504903PubTator, text miningPubMed
Late INa as a Therapeutic Target: New Strategies, Computational Modelling, Drug Development, and Clinical Translation.Med Res Rev202642464877PubTator, text miningPubMed
Common genetic variants of the cardiac sodium channel alter patient response to class 1b antiarrhythmics.J Precis Med (Amst)202642422555PubTator, text miningPubMed
A case report on αIN antibody-mediated paraneoplastic cerebellar ataxia.Clin Neurol Neurosurg202642361521PubTator, text miningPubMed
From Axonal Growth to Neurodegeneration: The Dual Role of Neurofilament Dynamics in Health and Disease.NeuroSci202642200920PubTator, text miningPubMed
Modes of onset of ventricular arrhythmias in J-wave syndromes: mechanistic insights from computational modeling.Am J Physiol Heart Circ Physiol202642141763PubTator, text miningPubMed
Chemically induced cardiotoxicity: Role of voltage dependent ion channels.Curr Top Membr202642082304PubTator, text miningPubMed

1 to 10 of 2,019

See all 2,019 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9118

GET https://conductscience.org/api/genes/v1/9118/patents?page=2