Gene · 9126
SMC3: structural maintenance of chromosomes 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SMC3: structural maintenance of chromosomes 3. Genes, record 9126. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9126
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9UQE7 | Structural maintenance of chromosomes protein 3 | 1,217 | 12 | Ensembl, GeneID, HGNC |
Source UniProt
Patents28
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 65690 | Q9UQE7 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 7929 | Q9UQE7 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 8019 | Q9UQE7 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 8019 | Q9UQE7 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 7929 | Q9UQE7 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 84694 | Q9UQE7 | Espacenet |
| US 11357853 B2 | 2022-06-14 | 30 | Q9UQE7 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 187665 | Q9UQE7 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 10682 | Q9UQE7 | Espacenet |
| WO 2020043864 A1 | 2020-03-05 | 2404 | Q9UQE7 | Espacenet |
1 to 10 of 28
See all 28 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,239
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SMC3 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 18 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 15 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 13 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 13 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 11 | 2025 |
| R01HG003143 | Structural Annotation of the Human Genome | 11 | 2025 |
| R01CA117830 | Epigenomic Control of KSHV Latency | 10 | 2025 |
| U10CA180821 | Alliance for Clinical Trials in Oncology Operations Center - GY11 Funded Extension | 10 | 2025 |
| U10CA180882 | Alliance Statistics and Data Management Center | 10 | 2025 |
| U24CA196171 | The Alliance NCTN Biorepository and Biospecimen Resource | 10 | 2025 |
1 to 10 of 2,239Source NIH's project files
See all 2,239 nih grantsPapers3,065
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
Discovery of cyanocarbonimidodithioates as novel non-hydroxamate zinc-binding groups for selective HDAC8 inhibition: Design, synthesis, biological evaluation, anticancer activity, and in silico studies. | Bioorg Chem | 2026 | 42767177 | PubTator, text mining | PubMed |
| Protamine gene expression is associated with sperm motility in rams: An integrative experimental and gene network analysis. | Anim Reprod Sci | 2026 | 42748838 | PubTator, text mining | PubMed |
| Design, synthesis, and screening of novel thienopyrimidine derivatives as PI3K/HDAC dual inhibitors against cervical cancer cells. | Eur J Med Chem | 2026 | 42715866 | PubTator, text mining | PubMed |
| A Novel De Novo STAG1 Variant at the RAD21 Binding Interface Is Associated With Hypoglycemia, Recurrent Fever, Immunodeficiency and Features of Classical Cohesinopathies. | Clin Genet | 2026 | 42713681 | PubTator, text mining | PubMed |
| Characterization of Protein Co-Localization and Histone Modifications at Enhancers Anchored in Chromatin Loops. | Biology (Basel) | 2026 | 42651636 | PubTator, text mining | PubMed |
| Exploration of non-hydroxamate based quinoline analogues as HDAC8 inhibitors. | RSC Adv | 2026 | 42614841 | PubTator, text mining | PubMed |
| Outer membrane as a drug target for the treatment of GNB infections. | Drug Discov Today | 2026 | 42586474 | PubTator, text mining | PubMed |
| Chromosome Architecture Defined by the Meiosis-Specific Cohesin in Mammalian Germ Cells. | Adv Exp Med Biol | 2026 | 42455438 | PubTator, text mining | PubMed |
| Development of Indole-3-yl-methylene-thiobarbital Derivatives as Inhibitors of HDAC8 Enzyme Activity. | J Med Chem | 2026 | 42406494 | PubTator, text mining | PubMed |
| Epigenetic regulation of cardiac physiology and pathophysiology: biological sex matters. | J Cardiovasc Aging | 2026 | 42369572 | PubTator, text mining | PubMed |
1 to 10 of 3,065
See all 3,065 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/9126
GET https://conductscience.org/api/genes/v1/9126/patents?page=2