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AIFM1: apoptosis inducing factor mitochondria associated 1

1 protein, 81 patents, 0 drugs, 0 trials, 2,693 NIH grants and 6,548 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolAIFM1HGNC
Nameapoptosis inducing factor mitochondria associated 1HGNC
NCBI Gene ID9131NCBI Gene
HGNC IDHGNC:8768HGNC
EnsemblENSG00000156709NCBI Gene
AliasesAIF, AUNX1, CMT2D, CMTX4, COWCK, COXPD6, DFNX5, NADMR, NAMSD, PDCD8, SEMDHLNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O95831Apoptosis-inducing factor 1, mitochondrial61326Ensembl, GeneID, HGNCUniProt

Patents 81

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-193322O95831Espacenet
JP 2025147176 A2025-10-0616525O95831Espacenet
JP 2025529142 A2025-09-04353O95831Espacenet
US 12371689 B22025-07-29353O95831Espacenet
JP 2025517970 A2025-06-123322O95831Espacenet
JP 2025062604 A2025-04-145862O95831Espacenet
JP 2025028160 A2025-02-2816525O95831Espacenet
KR 1020250010750 A2025-01-2116525O95831Espacenet
EP 4484957 A12025-01-0148O95831Espacenet
JP 2024123008 A2024-09-104868O95831Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2693

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant272,025NIH's project files
P30CA016059Massey Cancer Center - Cancer Center Support Grant182,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)152,025NIH's project files
P30CA008748Cancer Center Support Grant132,025NIH's project files
P01CA092584Structural Cell Biology of DNA Repair Machines102,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant82,025NIH's project files
P30AG028740University of Florida Older Americans Independence Center (OAIC)62,025NIH's project files
P30CA016086Cancer Center Support Grant62,025NIH's project files
R01DC012049Optimizing Genetic Testing for Deafness for Clinical Diagnostics62,025NIH's project files
R01NS067525Parthanatos, PAAN/MIF nuclease Activation in Ischemic Injury62,025NIH's project files

Papers 6548

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42792820PubTator, text miningPubMed
42772614PubTator, text miningPubMed
42764949PubTator, text miningPubMed
42676038PubTator, text miningPubMed
42675618PubTator, text miningPubMed
42653693PubTator, text miningPubMed
42630868PubTator, text miningPubMed
42524632PubTator, text miningPubMed
42518252PubTator, text miningPubMed
42413719PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license