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Gene · 9133

CCNB2: cyclin B2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CCNB2: cyclin B2. Genes, record 9133. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9133

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Gene

Symbol
CCNB2
HGNC
Name
cyclin B2
HGNC
NCBI Gene ID
9133
NCBI Gene
HGNC ID
HGNC:1580
HGNC
Ensembl
ENSG00000157456
NCBI Gene
Aliases
HsT17299
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O95067G2/mitotic-specific cyclin-B23980Ensembl, GeneID, HGNC

Source UniProt

Patents59

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-193364O95067Espacenet
EP 4641202 A22025-10-294692O95067Espacenet
JP 2025517970 A2025-06-123364O95067Espacenet
KR 1020250017231 A2025-02-044692O95067Espacenet
JP 2024123008 A2024-09-105712O95067Espacenet
JP 2023123507 A2023-09-0524O95067Espacenet
US 11708396 B22023-07-252172O95067Espacenet
US 11446398 B22022-09-2020981O95067Espacenet
JP 2022092366 A2022-06-22809O95067Espacenet
JP 2022524081 A2022-04-27123952O95067Espacenet

1 to 10 of 59

See all 59 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,401

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCCNB2 papersNewest fiscal year
P30CA008748Cancer Center Support Grant82025
P30CA076292Moffitt Cancer Center Support Grant72025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant62025
P30CA016672Cancer Center Support Grant62025
P30CA016058Cancer Center Support Grant52025
ZICES102445Gene Expression and Microarrays52025
P30ES007033University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment42025
P50CA136393Use of microfluidic tumor cultures to enable clinical trials of therapies for ovarian cancer42025
ZICHG200365NHGRI/DIR Microarray and single-cell Core42025
P30CA014236Cancer Center Support Grant (CCSG)32025

1 to 10 of 1,401Source NIH's project files

See all 1,401 nih grants

Papers2,908

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
[Identification of immune key genes in sepsis and the regulatory effects of dexmedetomidine based on transcriptome analysis and machine learning].Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi202642750326PubTator, text miningPubMed
Consensus subtypes and a generalizable prognostic signature defined by an R-loop score in hepatocellular carcinoma: Multi-omics analyses pinpoint KIF2A-positive proliferative tumor cells.Pathol Res Pract202642636674PubTator, text miningPubMed
A six-gene prognostic signature for aflatoxin B1-associated hepatocellular carcinoma identified through integrated bioinformatics and network toxicology.Transl Gastroenterol Hepatol202642592322PubTator, text miningPubMed
Adaptation of Non-Invasive Cancer Cells to 3D Collagen I Microenvironment Induces Transcriptional Reprogramming Accompanied by a More Complex RNA Landscape.Int J Mol Sci202642589561PubTator, text miningPubMed
Retraction Note: Knockdown of CCNB2 inhibits the tumorigenesis of gastric cancer by regulation of the PI3K/Akt pathway.Sci Rep202642552334PubTator, text miningPubMed
An Integrated Cellular Computational Pipeline Decodes Luteolin to Design Possible Allosteric CDK1/CYCLIN B1 Inhibitors That Overcome Breast Cancer Stemness.Pharmaceuticals (Basel)202642515730PubTator, text miningPubMed
An Interpretable Four-Gene Cell-Cycle Signature Links Malignant Progression to Adverse Survival in Adult Primary Diffuse Glioma: A CGGA Transcriptome Study.Genes (Basel)202642510873PubTator, text miningPubMed
Delafloxacin suppresses DEPDC1 expression and induces G2/M arrest in non-small cell lung cancer cells: A drug repurposing study.Smart Mol202642500733PubTator, text miningPubMed
Identification and validation of stemness-associated hub genes in cervical cancer: a bioinformatics and experimental study.World J Surg Oncol202642365339PubTator, text miningPubMed
Identification of genes differentially expressed in granulosa cells from women with high vs. low ovarian responsiveness.Front Reprod Health202642358728PubTator, text miningPubMed

1 to 10 of 2,908

See all 2,908 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9133

GET https://conductscience.org/api/genes/v1/9133/patents?page=2