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Gene · 9134

CCNE2: cyclin E2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CCNE2: cyclin E2. Genes, record 9134. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9134

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Gene

Symbol
CCNE2
HGNC
Name
cyclin E2
HGNC
NCBI Gene ID
9134
NCBI Gene
HGNC ID
HGNC:1590
HGNC
Ensembl
ENSG00000175305
NCBI Gene
Aliases
CYCE2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O96020G1/S-specific cyclin-E24041Ensembl, GeneID, HGNC

Source UniProt

Patents68

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-294166O96020Espacenet
EP 4641202 A22025-10-294843O96020Espacenet
JP 2025517969 A2025-06-124166O96020Espacenet
JP 2025024198 A2025-02-1911500O96020Espacenet
JP 2025024198 A2025-02-1911502O96020Espacenet
KR 1020250017231 A2025-02-044843O96020Espacenet
US 11976334 B22024-05-07128O96020Espacenet
US 11708396 B22023-07-252190O96020Espacenet
US 11708396 B22023-07-252194O96020Espacenet
US 11446398 B22022-09-2021060O96020Espacenet

1 to 10 of 68

See all 68 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,511

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCCNE2 papersNewest fiscal year
P30CA016672Cancer Center Support Grant312025
P30CA008748Cancer Center Support Grant162025
P30CA016058Cancer Center Support Grant102025
P30CA010815Consolidated Basic Cancer Research Program72025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant72025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant62025
P30CA033572Cancer Center Support Grant52025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202852025
P01AI127335Human Cytomegalovirus dysregulation of host hematopoietic progenitor cell signaling pathways to modulate latency and reactivation42025
P30CA013696Cancer Center Support Grant42025

1 to 10 of 1,511Source NIH's project files

See all 1,511 nih grants

Papers2,792

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
DIXDC1 Promotes Lymphatic Metastasis and Resistance to Cuproptosis in Bladder Cancer Through Mediating DLAT.Adv Sci (Weinh)202642658569PubTator, text miningPubMed
Feed restriction affects follicular development by regulating cell cycle progression in porcine mural granulosa cells.J Anim Sci Biotechnol202642482127PubTator, text miningPubMed
Self-organizing three-dimensional dermal papilla cell spheroids yield therapeutic extracellular vesicles that target hypertrophic scar regression via the miR-26a-5p/CCNE2 axis.Burns Trauma202642421776PubTator, text miningPubMed
Orientin inhibits cyclin E/cyclin A-CDK2 to induce growth arrest at senescence in human gastric cancer cells.Food Chem Toxicol202642303079PubTator, text miningPubMed
[MUTYH-APEX1 Axis Promotes Hepatocellular Carcinoma Progression and Therapeutic Resistance by Regulating Cell Cycle Proteins].Sichuan Da Xue Xue Bao Yi Xue Ban202642021884PubTator, text miningPubMed
RNA N6-methyladenosine (m6A) regulates cell cycle progression in diffuse midline glioma (DMG) and confers sensitivity to FTO inhibition.Cell Death Dis202641888518PubTator, text miningPubMed
Precision Design in Cancer Treatment: Cucurbitacin E Modulates AMPK, PGK1, and PKM2 to Optimize Radiation Efficacy in Melanoma.Curr Pharm Des202641832669PubTator, text miningPubMed
Hsa-microRNA-34a-5p inhibits virus-negative Merkel cell carcinoma cell proliferation and migration by regulating cell cycle- and EMT-related pathways and suppresses tumor spheroid formation.J Dermatol Sci202641820098PubTator, text miningPubMed
Understanding the Mechanisms of Human Liver Regeneration via Characterization of Circulating Extracellular Vesicles.Biomed Res Int202641810218PubTator, text miningPubMed
PVT1 lincRNA signals an androgen-dependent transcriptional activation program of oncogenes in prostate cancer cells.Int J Cancer202641792045PubTator, text miningPubMed

1 to 10 of 2,792

See all 2,792 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9134

GET https://conductscience.org/api/genes/v1/9134/patents?page=2