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CD2: CD2 molecule

1 protein, 215 patents, 2 drugs, 38 trials, 6,678 NIH grants and 15,189 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCD2HGNC
NameCD2 moleculeHGNC
NCBI Gene ID914NCBI Gene
HGNC IDHGNC:1639HGNC
EnsemblENSG00000116824NCBI Gene
AliasesLFA-2, SRBC, T11NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P06729T-cell surface antigen CD23517Ensembl, GeneID, HGNCUniProt

Patents 215

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4831196 A22026-10-2823P06729Espacenet
US 12624087 B22026-05-1223P06729Espacenet
US 12612446 B22026-04-28464P06729Espacenet
WO 2025252547 A12025-12-1110P06729Espacenet
EP 4660322 A12025-12-1010P06729Espacenet
EP 4650780 A22025-11-198627P06729Espacenet
WO 2025228986 A12025-11-0636P06729Espacenet
EP 4644537 A12025-11-0536P06729Espacenet
JP 2025166053 A2025-11-0523P06729Espacenet
EP 4641201 A22025-10-298795P06729Espacenet

Drugs 2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ALEFACEPTCHEMBL1201571T-cell surface antigen CD2 inhibitorINHIBITORChEMBL
SIPLIZUMABCHEMBL2108742T-cell surface antigen CD2 inhibitorINHIBITORChEMBL

Trials 38

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06972069SIPLIZUMABEARLY_PHASE1ClinicalTrials.gov
NCT06455280SIPLIZUMABPHASE1ClinicalTrials.gov
NCT06453668SIPLIZUMABPHASE1ClinicalTrials.gov
NCT06326476SIPLIZUMABEARLY_PHASE1ClinicalTrials.gov
NCT06078696SIPLIZUMABPHASE1/PHASE22026-02-27ClinicalTrials.gov
NCT06025110SIPLIZUMABPHASE2ClinicalTrials.gov
NCT05574335SIPLIZUMABPHASE1/PHASE2ClinicalTrials.gov
NCT01780454SIPLIZUMABPHASE1/PHASE22020-09-23ClinicalTrials.gov
NCT01445535SIPLIZUMABPHASE12020-08-18ClinicalTrials.gov
NCT01319851ALEFACEPT2015-03-09ClinicalTrials.gov

NIH grants 6678

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant752,025NIH's project files
P30CA008748Cancer Center Support Grant732,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)262,025NIH's project files
ZIAAI000249The Pathogenesis, Diagnosis, and Treatment of Systemic Mast Cell Disorders242,025NIH's project files
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success192,025NIH's project files
ZIABC011070Hematopathology Diagnosis192,025NIH's project files
P01CA065493Off-the-Shelf Immune Effector Cells for Hematological Malignancies182,025NIH's project files
ZIASC000550Lymphoma Disease Discovery and Definition182,025NIH's project files
P01AI045897A Tolerance Approach to Xenotransplantation172,025NIH's project files
P30CA014520UW Comprehensive Cancer Center Support172,025NIH's project files

Papers 15189

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818791PubTator, text miningPubMed
42815239PubTator, text miningPubMed
42811949PubTator, text miningPubMed
42808831PubTator, text miningPubMed
42808109PubTator, text miningPubMed
42798205PubTator, text miningPubMed
42776797PubTator, text miningPubMed
42768869PubTator, text miningPubMed
42765840PubTator, text miningPubMed
42762201PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license