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Gene · 91543

RSAD2: radical S-adenosyl methionine domain containing 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RSAD2: radical S-adenosyl methionine domain containing 2. Genes, record 91543. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/91543

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Gene

Symbol
RSAD2
HGNC
Name
radical S-adenosyl methionine domain containing 2
HGNC
NCBI Gene ID
91543
NCBI Gene
HGNC ID
HGNC:30908
HGNC
Ensembl
ENSG00000134321
NCBI Gene
Aliases
SAND, Viperin, cig33, cig5, vig1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8WXG1S-adenosylmethionine-dependent nucleotide dehydratase RSAD23610Ensembl, GeneID, HGNC

Source UniProt

Patents63

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 12545636 B22026-02-1026Q8WXG1Espacenet
JP 2026004568 A2026-01-1460839Q8WXG1Espacenet
EP 4641201 A22025-10-2910865Q8WXG1Espacenet
EP 4641202 A22025-10-295790Q8WXG1Espacenet
JP 2025517969 A2025-06-1210865Q8WXG1Espacenet
KR 1020250017231 A2025-02-045790Q8WXG1Espacenet
US 12215068 B22025-02-0426Q8WXG1Espacenet
JP 2024534697 A2024-09-2026Q8WXG1Espacenet
JP 2024533865 A2024-09-1226Q8WXG1Espacenet
US 11884978 B22024-01-30720Q8WXG1Espacenet

1 to 10 of 63

See all 63 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,059

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRSAD2 papersNewest fiscal year
P30DK034854Integrated Epithelial and Muscosal Biology132025
U19AI135972SARS-CoV adaptations through a Systems Biology Lens (SYBIL)92025
UL1TR001863Yale Clinical and Translational Science Award92025
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success82025
P30CA008748Cancer Center Support Grant72025
P51OD011132Emory National Primate Research Center72025
P30CA047904Cancer Center Support Grant62025
P30CA091842Cancer Center Support Grant62025
R01AI127372Human ISG15 and USP18 Deficiencies Underlying Type I Interferonopathies62025
U19AI057266Vaccine and Infection Induced Immunity in the Young and Aged62025

1 to 10 of 2,059Source NIH's project files

See all 2,059 nih grants

Papers3,037

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Selective Whole-Blood Expression of Interferon-Stimulated Genes and TLR3/TLR7 in Type 1 Diabetes with Minimal Enterovirus-Targeted Amplification in Whole Blood.Genes (Basel)202642792959PubTator, text miningPubMed
Optineurin Restricts ZIKV Replication Through Promoting IFN-Mediated JAK/STAT Signaling Pathway.J Med Virol202642747136PubTator, text miningPubMed
Methamphetamine enhances HIV infection of human iPSC-derived microglia.NeuroImmune Pharm Ther202642699847PubTator, text miningPubMed
Integrated Functional Characterization of a Panel of Clinical Orthoflavivirus Isolates Reveals Distinct Replication and Innate Immune Response Profiles in Human Keratinocytes.Viruses202642655646PubTator, text miningPubMed
Histopathological Assessment of IFI6- and RSAD2-DNA Aptamers in Oral Squamous Cell Carcinoma: A Preliminary Study Based on In Silico Analysis.Biomedicines202642652067PubTator, text miningPubMed
Lipid droplet dynamics control type I interferon responses and viperin expression to suppress viral replication.Vet Microbiol202642623889PubTator, text miningPubMed
Interferon-stimulated gene signature predicts clinical response to low-dose IL-2 in immune-mediated inflammatory diseases.Ann Rheum Dis202642618420PubTator, text miningPubMed
Integrative Bioinformatics and Machine Learning Analysis Identifies Novel Molecular Biomarkers in Prostate Adenocarcinoma.Int J Mol Sci202642589294PubTator, text miningPubMed
RSAD2/VIPERIN and CMPK2 coordinate an immunometabolic response to Epstein-Barr Virus.PLoS Pathog202642546073PubTator, text miningPubMed
Viperin suppresses goose astrovirus type 2 replication through inhibition of viral RdRP activity.Vet Res202642533335PubTator, text miningPubMed

1 to 10 of 3,037

See all 3,037 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/91543

GET https://conductscience.org/api/genes/v1/91543/patents?page=2