Gene · 9156
EXO1: exonuclease 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. EXO1: exonuclease 1. Genes, record 9156. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9156
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9UQ84 | Exonuclease 1 | 846 | 25 | Ensembl, GeneID, HGNC |
Source UniProt
Patents82
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12624353 B2 | 2026-05-12 | 3869 | Q9UQ84 | Espacenet |
| US 12624354 B2 | 2026-05-12 | 3869 | Q9UQ84 | Espacenet |
| JP 2026062659 A | 2026-04-10 | 3869 | Q9UQ84 | Espacenet |
| US 12570972 B2 | 2026-03-10 | 3869 | Q9UQ84 | Espacenet |
| US 12509680 B2 | 2025-12-30 | 3869 | Q9UQ84 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 653 | Q9UQ84 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 4360 | Q9UQ84 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4870 | Q9UQ84 | Espacenet |
| JP 2025100656 A | 2025-07-03 | 18 | Q9UQ84 | Espacenet |
| WO 2025137408 A1 | 2025-06-26 | 135 | Q9UQ84 | Espacenet |
1 to 10 of 82
See all 82 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,219
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | EXO1 papers | Newest fiscal year |
|---|---|---|---|
| P01CA092584 | Structural Cell Biology of DNA Repair Machines | 61 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 27 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 21 | 2025 |
| ZIAAG000741 | Roles Of DNA Helicases In Pathways Required For Maintenance Of Genomic Stability | 21 | 2025 |
| R01GM050006 | Enzymology of Mismatch Repair in Yeast | 18 | 2025 |
| ZIAAG000752 | Model Genetic Systems to Study DNA Repair | 14 | 2025 |
| ZIAAG000753 | Fanconi Anemia Pathway | 11 | 2025 |
| R01ES007061 | Mechanisms of DNA Double-strand Break End Resection and Repair Pathway Choice | 10 | 2025 |
| R01GM098535 | Molecular mechanisms of DNA damage signaling and repair | 10 | 2025 |
| P30CA033572 | Cancer Center Support Grant | 9 | 2025 |
1 to 10 of 2,219Source NIH's project files
See all 2,219 nih grantsPapers3,400
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| BUB1 and CDK4/6 Dual Inhibition Increases Radiation Sensitivity in Glioblastoma, Lung Cancer, and Triple-Negative Breast Cancer. | Biomedicines | 2026 | 42792682 | PubTator, text mining | PubMed |
| A phenotype- and potency-gated extracellular vesicle allocation hypothesis for autism. | Front Child Adolesc Psychiatry | 2026 | 42729530 | PubTator, text mining | PubMed |
| Suppression of transcription-replication conflicts by sequence-coordinated actions of TRDMT1 and MutLα. | Nat Commun | 2026 | 42706250 | PubTator, text mining | PubMed |
| DNA damage response genes in lung cancer: Diagnostic, prognostic, and therapeutic implications - A narrative review. | Crit Rev Oncol Hematol | 2026 | 42603641 | PubTator, text mining | PubMed |
| Experimental Investigation of Nanolayered Silver and MXene Coatings for Enhanced Energy Efficiency in Compact Heat Exchangers. | ACS Omega | 2026 | 42597894 | PubTator, text mining | PubMed |
| Bacterial and gut microbiota-derived extracellular vesicles as emerging sources of cancer biomarkers: molecular mechanisms, diagnostic approaches, and therapeutic applications. | Front Cell Infect Microbiol | 2026 | 42564071 | PubTator, text mining | PubMed |
| CTCF primes repressive chromatin for rapid BRCA1/BARD1 recruitment to drive homologous recombination repair of DNA double-strand breaks. | Nucleic Acids Res | 2026 | 42475683 | PubTator, text mining | PubMed |
| All-in-one exome sequencing approach for genetic testing of unexplained premature ovarian insufficiency. | Hum Reprod Open | 2026 | 42465592 | PubTator, text mining | PubMed |
| Integrative systematic review and transcriptomic -machine learning analysis of molecular signatures in metaplastic breast cancer. | Ecancermedicalscience | 2026 | 42416235 | PubTator, text mining | PubMed |
| Molecular effects of ovarian stimulation for fertility preservation in breast cancer: a paired-biopsy analysis. | ESMO Open | 2026 | 42413327 | PubTator, text mining | PubMed |
1 to 10 of 3,400
See all 3,400 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/9156
GET https://conductscience.org/api/genes/v1/9156/patents?page=2