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Gene · 9159

PCSK7: proprotein convertase subtilisin/kexin type 7

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PCSK7: proprotein convertase subtilisin/kexin type 7. Genes, record 9159. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9159

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Gene

Symbol
PCSK7
HGNC
Name
proprotein convertase subtilisin/kexin type 7
HGNC
NCBI Gene ID
9159
NCBI Gene
HGNC ID
HGNC:8748
HGNC
Ensembl
ENSG00000160613
NCBI Gene
Aliases
LPC, PC7, PC8, SPC7
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q16549Proprotein convertase subtilisin/kexin type 77850Ensembl, GeneID, HGNC

Source UniProt

Patents76

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4705273 A22026-03-11574Q16549Espacenet
EP 4640849 A22025-10-29810Q16549Espacenet
EP 4641201 A22025-10-295277Q16549Espacenet
JP 2025529142 A2025-09-043424Q16549Espacenet
US 12371689 B22025-07-293424Q16549Espacenet
JP 2025519096 A2025-06-24810Q16549Espacenet
JP 2025517969 A2025-06-125277Q16549Espacenet
US 12269897 B22025-04-08760Q16549Espacenet
JP 2025032204 A2025-03-1133045Q16549Espacenet
JP 2025506455 A2025-03-111Q16549Espacenet

1 to 10 of 76

See all 76 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,175

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePCSK7 papersNewest fiscal year
P30CA006927Comprehensive Cancer Center Program at Fox Chase52025
P30CA008748Cancer Center Support Grant52025
P30DK063491Diabetes Research Center (DRC)42025
P30CA047904Cancer Center Support Grant32025
K24HL136852Mentored Patient-Oriented Research for Preventing ASCVD Events22025
P01AG026276Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study22025
P30AG066444Alzheimer's Disease Research Center22025
P30CA033572Cancer Center Support Grant22025
P30CA036727Buffett Cancer Center Support Grant22025
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant22025

1 to 10 of 1,175Source NIH's project files

See all 1,175 nih grants

Papers1,683

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Association of three different dietary patterns with the metabolomic profiles of children: the BiomarKid project.Eur J Nutr202642730764PubTator, text miningPubMed
The interplay of air pollution with plasma neurodegenerative markers and metabolome for dementia, Parkinson's disease and all-cause mortality risks and transitions: The UK Biobank study.Ecotoxicol Environ Saf202642632170PubTator, text miningPubMed
Pyrogallol inhibits T cell lymphoma growth by mediating G2/M phase cell cycle arrest, apoptosis, glycolysis and immune evasion: an implication of AKT pathway.Cytotechnology202642471957PubTator, text miningPubMed
A speech prediction model based on codec modeling and transformer decoding.Comput Speech Lang202642343891PubTator, text miningPubMed
Human adipose-derived mesenchymal stem cells ameliorate Diabetic Kidney Disease by restoring macrophage efferocytosis.Stem Cell Res Ther202642316289PubTator, text miningPubMed
Metabolomic atlas of dengue virus infection reveals distinct circulating bioactive lipid signatures.PLoS Negl Trop Dis202642118780PubTator, text miningPubMed
Identification of lipid quantitative trait loci linked with cardiometabolic disease in Asian Indians and Europeans: A genome-wide association study and Mendelian randomization.PLoS Med202642024661PubTator, text miningPubMed
Metabolomics reveals LysoPC a C17:0 (LPC 17:0) as candidate biomarker for personalized medicine in morbid obesity.Front Med (Lausanne)202641982539PubTator, text miningPubMed
Secular Changes in Cranial Morphology and Pattern of Sexual Dimorphism in Modern Japanese: A Geometric Morphometric Analysis Using Post-Mortem Computed Tomography Data.Am J Biol Anthropol202641928728PubTator, text miningPubMed
In Vitro Modeling of Age-Associated Lipid Mediator's Impact on Vascular Biology Following Platelet Concentrate Transfusion.Aging Cell202641922292PubTator, text miningPubMed

1 to 10 of 1,683

See all 1,683 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9159

GET https://conductscience.org/api/genes/v1/9159/patents?page=2