Gene · 9159
PCSK7: proprotein convertase subtilisin/kexin type 7
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PCSK7: proprotein convertase subtilisin/kexin type 7. Genes, record 9159. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9159
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q16549 | Proprotein convertase subtilisin/kexin type 7 | 785 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents76
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4705273 A2 | 2026-03-11 | 574 | Q16549 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 810 | Q16549 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 5277 | Q16549 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 3424 | Q16549 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 3424 | Q16549 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 810 | Q16549 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 5277 | Q16549 | Espacenet |
| US 12269897 B2 | 2025-04-08 | 760 | Q16549 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 33045 | Q16549 | Espacenet |
| JP 2025506455 A | 2025-03-11 | 1 | Q16549 | Espacenet |
1 to 10 of 76
See all 76 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,175
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PCSK7 papers | Newest fiscal year |
|---|---|---|---|
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 4 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 3 | 2025 |
| K24HL136852 | Mentored Patient-Oriented Research for Preventing ASCVD Events | 2 | 2025 |
| P01AG026276 | Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study | 2 | 2025 |
| P30AG066444 | Alzheimer's Disease Research Center | 2 | 2025 |
| P30CA033572 | Cancer Center Support Grant | 2 | 2025 |
| P30CA036727 | Buffett Cancer Center Support Grant | 2 | 2025 |
| P30CA051008 | Georgetown University Lombardi Comprehensive Cancer Center Support Grant | 2 | 2025 |
1 to 10 of 1,175Source NIH's project files
See all 1,175 nih grantsPapers1,683
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Association of three different dietary patterns with the metabolomic profiles of children: the BiomarKid project. | Eur J Nutr | 2026 | 42730764 | PubTator, text mining | PubMed |
| The interplay of air pollution with plasma neurodegenerative markers and metabolome for dementia, Parkinson's disease and all-cause mortality risks and transitions: The UK Biobank study. | Ecotoxicol Environ Saf | 2026 | 42632170 | PubTator, text mining | PubMed |
| Pyrogallol inhibits T cell lymphoma growth by mediating G2/M phase cell cycle arrest, apoptosis, glycolysis and immune evasion: an implication of AKT pathway. | Cytotechnology | 2026 | 42471957 | PubTator, text mining | PubMed |
| A speech prediction model based on codec modeling and transformer decoding. | Comput Speech Lang | 2026 | 42343891 | PubTator, text mining | PubMed |
| Human adipose-derived mesenchymal stem cells ameliorate Diabetic Kidney Disease by restoring macrophage efferocytosis. | Stem Cell Res Ther | 2026 | 42316289 | PubTator, text mining | PubMed |
| Metabolomic atlas of dengue virus infection reveals distinct circulating bioactive lipid signatures. | PLoS Negl Trop Dis | 2026 | 42118780 | PubTator, text mining | PubMed |
| Identification of lipid quantitative trait loci linked with cardiometabolic disease in Asian Indians and Europeans: A genome-wide association study and Mendelian randomization. | PLoS Med | 2026 | 42024661 | PubTator, text mining | PubMed |
| Metabolomics reveals LysoPC a C17:0 (LPC 17:0) as candidate biomarker for personalized medicine in morbid obesity. | Front Med (Lausanne) | 2026 | 41982539 | PubTator, text mining | PubMed |
| Secular Changes in Cranial Morphology and Pattern of Sexual Dimorphism in Modern Japanese: A Geometric Morphometric Analysis Using Post-Mortem Computed Tomography Data. | Am J Biol Anthropol | 2026 | 41928728 | PubTator, text mining | PubMed |
| In Vitro Modeling of Age-Associated Lipid Mediator's Impact on Vascular Biology Following Platelet Concentrate Transfusion. | Aging Cell | 2026 | 41922292 | PubTator, text mining | PubMed |
1 to 10 of 1,683
See all 1,683 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/9159
GET https://conductscience.org/api/genes/v1/9159/patents?page=2