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Gene · 9170

LPAR2: lysophosphatidic acid receptor 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. LPAR2: lysophosphatidic acid receptor 2. Genes, record 9170. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9170

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Gene

Symbol
LPAR2
HGNC
Name
lysophosphatidic acid receptor 2
HGNC
NCBI Gene ID
9170
NCBI Gene
HGNC ID
HGNC:3168
HGNC
Ensembl
ENSG00000064547
NCBI Gene
Aliases
EDG-4, EDG4, LPA-2, LPA2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9HBW0Lysophosphatidic acid receptor 23482Ensembl, GeneID, HGNC

Source UniProt

Patents0

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

None in this release.

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,528

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleLPAR2 papersNewest fiscal year
P30CA016672Cancer Center Support Grant202025
R01DK080834Inhibition of an Apical cAMP/cGMP Transporter (MRP4) in the Gut Induces Diarrhea102025
P30CA008748Cancer Center Support Grant92025
P30CA016059Massey Cancer Center - Cancer Center Support Grant82025
P30CA046934University of Colorado Cancer Center Support Grant52025
P30DK034854Integrated Epithelial and Muscosal Biology42025
P30DK056341Washington University Nutrition Obesity Research Center42025
T32AI007405Training Program in Immunology42025
P30CA006927Comprehensive Cancer Center Program at Fox Chase32025
P30CA006973Regional Oncology Research Center32025

1 to 10 of 2,528Source NIH's project files

See all 2,528 nih grants

Papers3,539

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The hidden cost of antibiotics: microbial dysbiosis-induced SCFA imbalance and its underlying mechanisms.Front Immunol202642769955PubTator, text miningPubMed
LPA₃ signaling and biological functions: from physiological regulation to disease-targeted therapy.Mol Biol Rep202642742769PubTator, text miningPubMed
Universal pipeline for high-resolution GPCR structure determination.Nat Struct Mol Biol202642665663PubTator, text miningPubMed
Lactic acid exposure alters lysophosphatidic acid receptor-mediated regulation of growth and motility in pancreatic cancer cells.Mol Cell Biochem202642663874PubTator, text miningPubMed
Oxytocin Mitigates VEGF Expression in Differentiated RPE cells - A Novel Therapeutic Approach for Diabetic Retinopathy.Biomed Transl Sci202642583586PubTator, text miningPubMed
Dysbiosis-Associated Lysophosphatidic Acid Primes Immune Checkpoint Inhibitor-Induced Intestinal Barrier Dysfunction via the Lysophosphatidic Acid Receptor 2-Myosin Light Chain Kinase Axis.Cell Mol Gastroenterol Hepatol202642562136PubTator, text miningPubMed
Integrated analysis of cell-in-cell related genes and immune microenvironment in heart failure.Front Cell Dev Biol202642181687PubTator, text miningPubMed
Construction of an actin cytoskeleton-related gene signature for predicting prognosis and therapeutic response in glioblastoma: based on machine learning.Transl Cancer Res202642180858PubTator, text miningPubMed
Regulatory mechanisms of LGR4 on cancer and cancer stem cell properties.Discov Oncol202642174273PubTator, text miningPubMed
Annexin A1 and its membrane receptor complex: Implications for immune regulation and autoimmune disease mechanisms.Autoimmun Rev202642162635PubTator, text miningPubMed

1 to 10 of 3,539

See all 3,539 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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