Gene · 91746
YTHDC1: YTH N6-methyladenosine RNA binding protein C1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. YTHDC1: YTH N6-methyladenosine RNA binding protein C1. Genes, record 91746. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/91746
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q96MU7 | YTH domain-containing protein 1 | 727 | 108 | Ensembl, GeneID, HGNC |
Source UniProt
Patents25
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4641201 A2 | 2025-10-29 | 6166 | Q96MU7 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 6166 | Q96MU7 | Espacenet |
| JP 2024530931 A | 2024-08-27 | 17 | Q96MU7 | Espacenet |
| EP 4380580 A2 | 2024-06-12 | 17 | Q96MU7 | Espacenet |
| KR 1020240083171 A | 2024-06-11 | 17 | Q96MU7 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 98248 | Q96MU7 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 98254 | Q96MU7 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 201219 | Q96MU7 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 201225 | Q96MU7 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 12716 | Q96MU7 | Espacenet |
1 to 10 of 25
See all 25 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants713
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | YTHDC1 papers | Newest fiscal year |
|---|---|---|---|
| RM1HG008935 | Center for dynamic RNA epitranscriptomes - Renewal | 15 | 2025 |
| R01CA186702 | Mechanisms of epitranscriptomic regulation in cancer | 7 | 2025 |
| R01CA271497 | The role and therapeutic potential of IGF2BP2 in MLL-rearranged leukemia | 6 | 2025 |
| R01GM056927 | Control of Translation in Herpesvirus Infected Cells - Resubmission - 1 | 6 | 2025 |
| R01AI152543 | EPITRANSCRIPTOMIC REGULATION OF CYTOMEGALOVIRUS INFECTION | 5 | 2025 |
| R35GM134744 | Epigenetic regulations of DNA and histone methylation and deMethylation: Structures and Mechanisms | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| R01CA096512 | Cell model for KSHV infection and genetic manipulation | 4 | 2025 |
| P30AI064518 | Center for AIDS Research | 3 | 2025 |
1 to 10 of 713Source NIH's project files
See all 713 nih grantsPapers2,550
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A positive feedback loop between YTHDC1 and EP300 drives multiple myeloma tumorigenesis. | Oncogene | 2026 | 42791263 | PubTator, text mining | PubMed |
| Regulation and function of the HPV16 CircE7 RNA. | J Virol | 2026 | 42752189 | PubTator, text mining | PubMed |
| METTL7B attenuates pathological cardiac hypertrophy via m6A-associated regulation of HK3. | Mol Cell Biochem | 2026 | 42742854 | PubTator, text mining | PubMed |
| RNA m⁶A modification and its regulatory factors are altered in granulosa cells from women with PMOS. | J Assist Reprod Genet | 2026 | 42687053 | PubTator, text mining | PubMed |
| RNA Labeling with Fluorophore. | Methods Mol Biol | 2026 | 42681511 | PubTator, text mining | PubMed |
| YTHDC1 functions as a molecular chaperone to suppress ALS-linked hnRNPA1 mutants from aggregation. | Nat Commun | 2026 | 42680774 | PubTator, text mining | PubMed |
| YTHDC1 Orchestrates Glucose and Glutamate Rewiring to Overcome Lethal Metabolic Stress in Triple-Negative Breast Cancer. | Adv Sci (Weinh) | 2026 | 42669610 | PubTator, text mining | PubMed |
| AS-TLC-Based High-Throughput Screening Integrated with CuAAC Optimization Strategy Facilitates the Rapid Discovery of YTHDC1 Inhibitor. | Adv Sci (Weinh) | 2026 | 42658481 | PubTator, text mining | PubMed |
| An Explicit Interaction-Prompted Diffusion Framework for High-Fidelity 3D Molecular Generation. | J Am Chem Soc | 2026 | 42619129 | PubTator, text mining | PubMed |
| O-GlcNAc clusters in intrinsically disordered regions regulate transcriptional condensates and gene control. | Protein Cell | 2026 | 42530374 | PubTator, text mining | PubMed |
1 to 10 of 2,550
See all 2,550 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/91746
GET https://conductscience.org/api/genes/v1/91746/patents?page=2