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Gene · 91746

YTHDC1: YTH N6-methyladenosine RNA binding protein C1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. YTHDC1: YTH N6-methyladenosine RNA binding protein C1. Genes, record 91746. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/91746

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Gene

Symbol
YTHDC1
HGNC
Name
YTH N6-methyladenosine RNA binding protein C1
HGNC
NCBI Gene ID
91746
NCBI Gene
HGNC ID
HGNC:30626
HGNC
Ensembl
ENSG00000083896
NCBI Gene
Aliases
KIAA1966, YT521, YT521-B
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q96MU7YTH domain-containing protein 1727108Ensembl, GeneID, HGNC

Source UniProt

Patents25

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-296166Q96MU7Espacenet
JP 2025517969 A2025-06-126166Q96MU7Espacenet
JP 2024530931 A2024-08-2717Q96MU7Espacenet
EP 4380580 A22024-06-1217Q96MU7Espacenet
KR 1020240083171 A2024-06-1117Q96MU7Espacenet
US 11446398 B22022-09-2098248Q96MU7Espacenet
US 11446398 B22022-09-2098254Q96MU7Espacenet
JP 2022524081 A2022-04-27201219Q96MU7Espacenet
JP 2022524081 A2022-04-27201225Q96MU7Espacenet
US 11078247 B22021-08-0312716Q96MU7Espacenet

1 to 10 of 25

See all 25 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants713

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleYTHDC1 papersNewest fiscal year
RM1HG008935Center for dynamic RNA epitranscriptomes - Renewal152025
R01CA186702Mechanisms of epitranscriptomic regulation in cancer72025
R01CA271497The role and therapeutic potential of IGF2BP2 in MLL-rearranged leukemia62025
R01GM056927Control of Translation in Herpesvirus Infected Cells - Resubmission - 162025
R01AI152543EPITRANSCRIPTOMIC REGULATION OF CYTOMEGALOVIRUS INFECTION52025
R35GM134744Epigenetic regulations of DNA and histone methylation and deMethylation: Structures and Mechanisms52025
P30CA008748Cancer Center Support Grant42025
P30CA016672Cancer Center Support Grant42025
R01CA096512Cell model for KSHV infection and genetic manipulation42025
P30AI064518Center for AIDS Research32025

1 to 10 of 713Source NIH's project files

See all 713 nih grants

Papers2,550

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A positive feedback loop between YTHDC1 and EP300 drives multiple myeloma tumorigenesis.Oncogene202642791263PubTator, text miningPubMed
Regulation and function of the HPV16 CircE7 RNA.J Virol202642752189PubTator, text miningPubMed
METTL7B attenuates pathological cardiac hypertrophy via m6A-associated regulation of HK3.Mol Cell Biochem202642742854PubTator, text miningPubMed
RNA m⁶A modification and its regulatory factors are altered in granulosa cells from women with PMOS.J Assist Reprod Genet202642687053PubTator, text miningPubMed
RNA Labeling with Fluorophore.Methods Mol Biol202642681511PubTator, text miningPubMed
YTHDC1 functions as a molecular chaperone to suppress ALS-linked hnRNPA1 mutants from aggregation.Nat Commun202642680774PubTator, text miningPubMed
YTHDC1 Orchestrates Glucose and Glutamate Rewiring to Overcome Lethal Metabolic Stress in Triple-Negative Breast Cancer.Adv Sci (Weinh)202642669610PubTator, text miningPubMed
AS-TLC-Based High-Throughput Screening Integrated with CuAAC Optimization Strategy Facilitates the Rapid Discovery of YTHDC1 Inhibitor.Adv Sci (Weinh)202642658481PubTator, text miningPubMed
An Explicit Interaction-Prompted Diffusion Framework for High-Fidelity 3D Molecular Generation.J Am Chem Soc202642619129PubTator, text miningPubMed
O-GlcNAc clusters in intrinsically disordered regions regulate transcriptional condensates and gene control.Protein Cell202642530374PubTator, text miningPubMed

1 to 10 of 2,550

See all 2,550 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/91746

GET https://conductscience.org/api/genes/v1/91746/patents?page=2