Gene · 91807
MYLK3: myosin light chain kinase 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MYLK3: myosin light chain kinase 3. Genes, record 91807. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/91807
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q32MK0 | Myosin light chain kinase 3 | 819 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents23
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 54622 | Q32MK0 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 11658 | Q32MK0 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2764 | Q32MK0 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 2764 | Q32MK0 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 11658 | Q32MK0 | Espacenet |
| JP 2023123507 A | 2023-09-05 | 56 | Q32MK0 | Espacenet |
| JP 2023123507 A | 2023-09-05 | 57 | Q32MK0 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 54358 | Q32MK0 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 157329 | Q32MK0 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 7177 | Q32MK0 | Espacenet |
1 to 10 of 23
See all 23 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,188
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MYLK3 papers | Newest fiscal year |
|---|---|---|---|
| R01DK061931 | Mechanisms and pathophysiologic impact of claudin-2 modulation | 17 | 2025 |
| R01DK068271 | Therapeutic targeting of protein interactions to reverse MLCK1-mediated intestinal barrier loss and ameliorate disease. | 15 | 2025 |
| P30CA014599 | Cancer Center Support Grant | 7 | 2025 |
| P30DK042086 | Center for Interdisciplinary Study of Inflammatory Intestinal DIsorders (C-IID) | 6 | 2025 |
| P30DK034854 | Integrated Epithelial and Muscosal Biology | 5 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 4 | 2025 |
| P01HL126609 | Cytoskeletal Regulation of Lung Endothelial Pathobiology in ARDS | 3 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| P30EY005722 | Center Core Grant for Vision Research | 3 | 2025 |
1 to 10 of 1,188Source NIH's project files
See all 1,188 nih grantsPapers1,557
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Mechanisms related to increased susceptibility of the elderly lung to ventilator-induced lung injury: A scoping review. | Exp Gerontol | 2026 | 42735803 | PubTator, text mining | PubMed |
| An Updated Evidence Assessment of the Genetic Causes of Dilated Cardiomyopathy. | Circulation | 2026 | 42708185 | PubTator, text mining | PubMed |
| Osimertinib-Associated Cardiotoxicity in EGFR-Mutant Non-Small Cell Lung Cancer: Mechanisms, Phenotypes, and Surveillance. | Cardiol Rev | 2026 | 42636333 | PubTator, text mining | PubMed |
| Dysregulated bile acid metabolism impairs intestinal barrier integrity via defective GPBAR1 signaling in low-birth-weight suckling piglet. | Anim Nutr | 2026 | 42602664 | PubTator, text mining | PubMed |
| GPR56 regulates the expression of key androgen-target genes via G13-Rho-PKN1 axis and is overexpressed in prostate cancer. | J Steroid Biochem Mol Biol | 2026 | 42498205 | PubTator, text mining | PubMed |
| Coronary Artery Vasospasm: Cellular and Molecular Insights. | Cells | 2026 | 42439622 | PubTator, text mining | PubMed |
| Tamoxifen Modulates Actin Stress Fibre Dynamics Through c-Src-MLCK Signalling in Breast Cancer Cells. | Cell Biol Int | 2026 | 42187620 | PubTator, text mining | PubMed |
| Xylooligosaccharides ameliorate intestinal barrier injury by inhibiting apoptosis, RhoA/ROCK/MLCK signaling and NKG2DLs in intestinal epithelial cells. | Food Res Int | 2026 | 42116516 | PubTator, text mining | PubMed |
| Thrombin-mediated increased permeability of blood-brain barrier in diquat poisoning: Mechanistic insights and potential therapeutic targets. | Ecotoxicol Environ Saf | 2026 | 41926806 | PubTator, text mining | PubMed |
| Chaperonin in health and disease. | Mol Biomed | 2026 | 41920440 | PubTator, text mining | PubMed |
1 to 10 of 1,557
See all 1,557 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/91807
GET https://conductscience.org/api/genes/v1/91807/patents?page=2