Gene · 9188
DDX21: DExD-box helicase 21
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. DDX21: DExD-box helicase 21. Genes, record 9188. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9188
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9NR30 | Nucleolar RNA helicase 2 | 783 | 5 | Ensembl, GeneID, HGNC |
Source UniProt
Patents16
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 43130 | Q9NR30 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 7034 | Q9NR30 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 6915 | Q9NR30 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 5216 | Q9NR30 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 6915 | Q9NR30 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 7034 | Q9NR30 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 5216 | Q9NR30 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 22722 | Q9NR30 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 125693 | Q9NR30 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 2960 | Q9NR30 | Espacenet |
1 to 10 of 16
See all 16 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,004
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | DDX21 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| R01DK069710 | The Role of Nuclear PARPs in Signal-Regulated Transcription | 6 | 2025 |
| P30CA142543 | UT Southwestern Medical Center Simmons Comprehensive Cancer Center | 5 | 2025 |
| P01AI063302 | The intersection of innate and adaptive immunity to intracellular pathogens | 3 | 2025 |
| P01CA092584 | Structural Cell Biology of DNA Repair Machines | 3 | 2025 |
| P30CA036727 | Buffett Cancer Center Support Grant | 3 | 2025 |
| P30CA091842 | Cancer Center Support Grant | 3 | 2025 |
| P30ES019776 | HERCULES: Exposome Research Center | 3 | 2025 |
| T32AI060537 | Integrative Microbiology Program | 3 | 2025 |
1 to 10 of 1,004Source NIH's project files
See all 1,004 nih grantsPapers1,289
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Genome-Wide CRISPR Screens Identify Genome Stability as Regulator of the Cellular Sensitivity to Environmentally Relevant Bisphenol A Exposure. | Biomolecules | 2026 | 42793135 | PubTator, text mining | PubMed |
| DDX21 Enhances Radiosensitivity in Head and Neck Squamous Cell Carcinoma by Suppressing MK2-Mediated DNA Damage Response. | Adv Sci (Weinh) | 2026 | 42750169 | PubTator, text mining | PubMed |
| An ATP-Driven N Protein-DDX21 Molecular Switch Dynamically Controls SARS-CoV-2 RNA G-Quadruplex Heterogeneity. | Adv Sci (Weinh) | 2026 | 42750138 | PubTator, text mining | PubMed |
| KPNA1/importin α5 localizes to the nucleolus and associates with box C/D snoRNP complexes. | Biochem Biophys Res Commun | 2026 | 42659866 | PubTator, text mining | PubMed |
| Plakophilin 1 suppresses keratinocyte innate immune responses through DExD/H helicases. | Cell Mol Immunol | 2026 | 42618693 | PubTator, text mining | PubMed |
| R-loops in colorectal cancer: mechanisms, mapping strategies, and therapeutic opportunities. | Mol Biol Rep | 2026 | 42593691 | PubTator, text mining | PubMed |
| Histone Lactylation Mediated by circRNA-Facilitated FXR1 Phase Separation Promotes Colorectal Cancer Progression. | Cancer Res | 2026 | 42554628 | PubTator, text mining | PubMed |
| Human RPL7 and DDX21 function synergistically with HTLV-1 Gag to overcome genomic RNA structural barriers that block tRNAPro primer annealing. | Nucleic Acids Res | 2026 | 42444604 | PubTator, text mining | PubMed |
| The complete mitochondrial genome of the Boulenophrys xianjuensis (Anura: Megophryidae). | Mitochondrial DNA B Resour | 2026 | 42370214 | PubTator, text mining | PubMed |
| DDX21 Promotes Breast Cancer Growth and Metastasis via Stimulating RNAPII Elongation During Hypoxia. | MedComm (2020) | 2026 | 42311859 | PubTator, text mining | PubMed |
1 to 10 of 1,289
See all 1,289 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/9188
GET https://conductscience.org/api/genes/v1/9188/patents