Gene · 9201
DCLK1: doublecortin like kinase 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. DCLK1: doublecortin like kinase 1. Genes, record 9201. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9201
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O15075 | Serine/threonine-protein kinase DCLK1 | 740 | 11 | Ensembl, GeneID, HGNC |
Source UniProt
Patents30
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 44234 | O15075 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 7805 | O15075 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 7890 | O15075 | Espacenet |
| US 12415867 B2 | 2025-09-16 | 51 | O15075 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1224 | O15075 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1224 | O15075 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 7890 | O15075 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 7805 | O15075 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 27115 | O15075 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 27115 | O15075 | Espacenet |
1 to 10 of 30
See all 30 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,593
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | DCLK1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA168524 | The University of Kansas Cancer Center | 14 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 10 | 2025 |
| P30CA225520 | Stephenson Cancer Center - Cancer Center Support Grant | 9 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 9 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| R35CA210088 | The role of stem cells and the microenvironment in gastrointestinal cancers | 6 | 2025 |
| U01CA210240 | Pancreatic Cancer Detection Consortium | 6 | 2025 |
| P30DK052574 | Host-environment interactions in the pathophysiology of digestive disease | 5 | 2025 |
| P30DK078392 | Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease | 5 | 2025 |
1 to 10 of 1,593Source NIH's project files
See all 1,593 nih grantsPapers1,726
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| CPT1A-mediated IDO1 succinylation shapes EGFRvIII-driven resistance to tumor electric field therapy in glioblastoma. | Nat Commun | 2026 | 42806046 | PubTator, text mining | PubMed |
| Tuft cells contribute to the pathogenesis of human primary and experimental murine Sjögren's disease. | J Dent Sci | 2026 | 42688877 | PubTator, text mining | PubMed |
| SEC14L2 contributes to tumor progression by enhancing USP5-driven RBM3 deubiquitination in pancreatic ductal adenocarcinoma. | Oncogene | 2026 | 42649370 | PubTator, text mining | PubMed |
| Dietary vitamin A restricts intestinal tuft cell differentiation. | Cell Rep | 2026 | 42593965 | PubTator, text mining | PubMed |
| Immunohistochemistry-based molecular subtypes and stromal tumor-infiltrating lymphocytes in triple-negative breast cancer: a chemotherapy-only cohort. | Oncologist | 2026 | 42587422 | PubTator, text mining | PubMed |
| Cross-species functional analysis of a de novo DCLK1 variant associated with a neurodevelopmental disorder. | Res Sq | 2026 | 42539103 | PubTator, text mining | PubMed |
| Transcriptome profiling of ocular surface ectoderm derived from embryonic stem cells, and identification of CACNG6 and AQP3 as its surface markers. | Int J Ophthalmol | 2026 | 42523845 | PubTator, text mining | PubMed |
| MEK1 as a Synthetic Lethal Target with Cabozantinib in Renal Cell Carcinoma: Insights from CRISPR/Cas9 Screening. | Genes (Basel) | 2026 | 42510829 | PubTator, text mining | PubMed |
| DCLK1 regulates stemness and IL-6/STAT3-dependent metastatic niche formation in chemoresistant ovarian cancer. | J Exp Clin Cancer Res | 2026 | 42210222 | PubTator, text mining | PubMed |
| Smooth muscle cells transiently acquire a CD34+ progenitor state upon injury to drive pathological vascular remodeling. | Cell Stem Cell | 2026 | 42190659 | PubTator, text mining | PubMed |
1 to 10 of 1,726
See all 1,726 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/9201
GET https://conductscience.org/api/genes/v1/9201/patents?page=2