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Gene · 9201

DCLK1: doublecortin like kinase 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DCLK1: doublecortin like kinase 1. Genes, record 9201. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9201

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Gene

Symbol
DCLK1
HGNC
Name
doublecortin like kinase 1
HGNC
NCBI Gene ID
9201
NCBI Gene
HGNC ID
HGNC:2700
HGNC
Ensembl
ENSG00000133083
NCBI Gene
Aliases
CL1, CLICK1, DCAMKL1, DCDC3A, DCLK, KIAA0369
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O15075Serine/threonine-protein kinase DCLK174011Ensembl, GeneID, HGNC

Source UniProt

Patents30

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1444234O15075Espacenet
EP 4650780 A22025-11-197805O15075Espacenet
EP 4641201 A22025-10-297890O15075Espacenet
US 12415867 B22025-09-1651O15075Espacenet
JP 2025529142 A2025-09-041224O15075Espacenet
US 12371689 B22025-07-291224O15075Espacenet
JP 2025517969 A2025-06-127890O15075Espacenet
JP 2025517970 A2025-06-127805O15075Espacenet
JP 2025032204 A2025-03-1127115O15075Espacenet
EP 4461818 A22024-11-1327115O15075Espacenet

1 to 10 of 30

See all 30 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,593

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDCLK1 papersNewest fiscal year
P30CA168524The University of Kansas Cancer Center142025
P30CA068485Cancer Center Support Grant102025
P30CA225520Stephenson Cancer Center - Cancer Center Support Grant92025
P30DK058404Molecular and Cellular Basis for Digestive Diseases92025
P30CA008748Cancer Center Support Grant62025
P30CA016672Cancer Center Support Grant62025
R35CA210088The role of stem cells and the microenvironment in gastrointestinal cancers62025
U01CA210240Pancreatic Cancer Detection Consortium62025
P30DK052574Host-environment interactions in the pathophysiology of digestive disease52025
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease52025

1 to 10 of 1,593Source NIH's project files

See all 1,593 nih grants

Papers1,726

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
CPT1A-mediated IDO1 succinylation shapes EGFRvIII-driven resistance to tumor electric field therapy in glioblastoma.Nat Commun202642806046PubTator, text miningPubMed
Tuft cells contribute to the pathogenesis of human primary and experimental murine Sjögren's disease.J Dent Sci202642688877PubTator, text miningPubMed
SEC14L2 contributes to tumor progression by enhancing USP5-driven RBM3 deubiquitination in pancreatic ductal adenocarcinoma.Oncogene202642649370PubTator, text miningPubMed
Dietary vitamin A restricts intestinal tuft cell differentiation.Cell Rep202642593965PubTator, text miningPubMed
Immunohistochemistry-based molecular subtypes and stromal tumor-infiltrating lymphocytes in triple-negative breast cancer: a chemotherapy-only cohort.Oncologist202642587422PubTator, text miningPubMed
Cross-species functional analysis of a de novo DCLK1 variant associated with a neurodevelopmental disorder.Res Sq202642539103PubTator, text miningPubMed
Transcriptome profiling of ocular surface ectoderm derived from embryonic stem cells, and identification of CACNG6 and AQP3 as its surface markers.Int J Ophthalmol202642523845PubTator, text miningPubMed
MEK1 as a Synthetic Lethal Target with Cabozantinib in Renal Cell Carcinoma: Insights from CRISPR/Cas9 Screening.Genes (Basel)202642510829PubTator, text miningPubMed
DCLK1 regulates stemness and IL-6/STAT3-dependent metastatic niche formation in chemoresistant ovarian cancer.J Exp Clin Cancer Res202642210222PubTator, text miningPubMed
Smooth muscle cells transiently acquire a CD34+ progenitor state upon injury to drive pathological vascular remodeling.Cell Stem Cell202642190659PubTator, text miningPubMed

1 to 10 of 1,726

See all 1,726 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9201

GET https://conductscience.org/api/genes/v1/9201/patents?page=2