Gene · 9211
LGI1: leucine rich glioma inactivated 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. LGI1: leucine rich glioma inactivated 1. Genes, record 9211. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9211
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O95970 | Leucine-rich glioma-inactivated protein 1 | 557 | 9 | Ensembl, GeneID, HGNC |
Source UniProt
Patents124
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 51405 | O95970 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 8941 | O95970 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 9193 | O95970 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 7817 | O95970 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6884 | O95970 | Espacenet |
| WO 2025166063 A1 | 2025-08-07 | 16 | O95970 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6884 | O95970 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 9193 | O95970 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 8941 | O95970 | Espacenet |
| EP 4551941 A2 | 2025-05-14 | 28 | O95970 | Espacenet |
1 to 10 of 124
See all 124 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants526
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | LGI1 papers | Newest fiscal year |
|---|---|---|---|
| R01NS126227 | Seronegative Autoimmune Encephalopathies: Biomarker Discovery, Validation & Deep Phenotyping | 9 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 7 | 2025 |
| P01AG026276 | Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study | 3 | 2025 |
| P30AG066444 | Alzheimer's Disease Research Center | 3 | 2025 |
| R01NS029709 | Excitability and Plasticity of Developing Epileptic Brain | 3 | 2025 |
| P01AI073693 | Anti-NMDA Receptor Antibodies in Adult Brain Dysfunction: Lessons from Lupus | 2 | 2025 |
| P30AG062677 | Mayo Alzheimer's Disease Research Center | 2 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 2 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 2 | 2025 |
| P30CA034196 | Cancer Center Support (CORE) Grant | 2 | 2025 |
1 to 10 of 526Source NIH's project files
See all 526 nih grantsPapers3,019
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Immune dysregulation and epileptogenesis. | Neurol Sci | 2026 | 42820995 | PubTator, text mining | PubMed |
| Beyond Nerve Hyperexcitability: Potential Implications of Cerebrospinal Fluid CASPR2 Antibodies for Central Pain Processing in Isaacs Syndrome: A Case-Based Systematic Review. | Pain Ther | 2026 | 42809178 | PubTator, text mining | PubMed |
| Autoimmune encephalitis and gastrointestinal inflammation: Building evidence for a gut-brain connection. | J Neuroimmunol | 2026 | 42785101 | PubTator, text mining | PubMed |
| Antibody-Dependent Cellular Phagocytosis and Cytotoxicity in Patients With LGI1 and CASPR2 Encephalitis. | Neurol Neuroimmunol Neuroinflamm | 2026 | 42777167 | PubTator, text mining | PubMed |
| Structural Brain Changes Are Linked to Clinical and Cognitive Outcomes in Anti-LGI1 Encephalitis. | Neurol Neuroimmunol Neuroinflamm | 2026 | 42753224 | PubTator, text mining | PubMed |
| Hippocampal texture asymmetry features on 18F-FDG PET differentiating anti-LGI1 and anti-GABABR encephalitis. | Front Immunol | 2026 | 42712541 | PubTator, text mining | PubMed |
| Autoimmune Encephalitis: A Case Series from a Tertiary Care Center in South India. | Neurol India | 2026 | 42700126 | PubTator, text mining | PubMed |
| Olfactory Hallucinations as the Initial Symptom of Anti-Leucine-Rich Glioma-Inactivated 1 Antibody Encephalitis: A Case Report and Review of the Literature. | Cureus | 2026 | 42688849 | PubTator, text mining | PubMed |
| Autoimmune-associated epilepsy: definitions and diagnosis - a narrative review. | Arq Neuropsiquiatr | 2026 | 42674427 | PubTator, text mining | PubMed |
| [Anti-LGI1 antibody encephalitis: A monocentric retrospective series of seven patients]. | Rev Med Interne | 2026 | 42660711 | PubTator, text mining | PubMed |
1 to 10 of 3,019
See all 3,019 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/9211
GET https://conductscience.org/api/genes/v1/9211/patents?page=2