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MTDH: metadherin
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Gene · 92140

Papers2,305

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,305

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TitleJournalYearPMIDFound bySource
Integrated roles of miR-125b, miR-375, and miR-451 in breast cancer chemoresistance: mechanistic insights and translational implications.Mol Biol Rep202642684565PubTator, text miningPubMed
USP14 competitively binds to FBXW7 to stabilize MTDH and promotes metastasis and drug resistance of head and neck squamous cell carcinoma.Proc Natl Acad Sci U S A202642616774PubTator, text miningPubMed
AEG-1/MTDH: A central regulator of tumor progression, metabolic adaptation, and therapeutic resistance in gliomas.Tissue Cell202642570368PubTator, text miningPubMed
Molecular Pathophysiology of Hepatocellular Carcinoma: From Metabolic Inflammation to Therapeutic Targets.Cancers (Basel)202642512398PubTator, text miningPubMed
Structure-guided identification of 2-arylbenzothiazoles as disruptors of the oncogenic MTDH-SND1 protein-protein interaction.Arch Biochem Biophys202642498240PubTator, text miningPubMed
Recent advances in immunotherapy for breast cancer: An updated review.Crit Rev Oncol Hematol202642480964PubTator, text miningPubMed
Beyond VEGF: AEG-1/MTDH as a Systems-Level Orchestrator of Angiogenesis in Hepatocellular Carcinoma.Cells202642439688PubTator, text miningPubMed
Structure-Based Discovery of N-Aryl-N'-Heteroaryl Ureas as Disruptors of the Oncogenic MTDH-SND1 Protein-Protein Interaction: In Silico Insights and Biochemical Validation.Arch Pharm (Weinheim)202642397067PubTator, text miningPubMed
CAF-derived extracellular vesicle-associated LINC02420 links stromal communication to HIF1A-dependent glycolytic regulation in head and neck cancer.Cancer Lett202642296563PubTator, text miningPubMed
Metadherin: A pivotal oncogene and therapeutic target in head and neck cancer - a systematic review.Jpn Dent Sci Rev202642294496PubTator, text miningPubMed
Real-world-data for phenotypes and genotypes of rare monogenic genetic epilepsies and genes of uncertain significance for epilepsy.Epilepsia Open202642220229PubTator, text miningPubMed
LDLRAD2 drives glycolysis and angiogenesis to promote extramedullary infiltration in acute myeloid leukemia.iScience202642211128PubTator, text miningPubMed
1H-Indazole-3-Carboxylic Acid Derivatives as Disruptors of the Oncogenic MTDH-SND1 Protein-Protein Interaction: An In Silico-to-In Vitro Study.Cell Biochem Biophys202642210006PubTator, text miningPubMed
Phosphorylation of AEG-1 suppresses NF-κB signaling in gastric cancer.Mol Biol Rep202642189296PubTator, text miningPubMed
Experimental Validation and Bioinformatics Analysis Elucidate the Role of MTDH-Mediated PTEN Ubiquitination and Degradation in Podocyte Injury in Diabetic Kidney Disease.Hum Mutat202642147815PubTator, text miningPubMed
Identify MTDH as a Key Gene of Radio-Resistance in Colorectal Cancer Based on Multi-Omics and Experimental Validation.Oncol Res202642065055PubTator, text miningPubMed
Integrating single-cell and bulk transcriptomes to reveal prognostic and immunological features of ecDNA-related genes in osteosarcoma.Cancer Immunol Immunother202642047819PubTator, text miningPubMed
let-7d Suppresses Proliferation and Invasion and Promotes Apoptosis of Meningioma by Targeting AEG-1 [Retraction].Onco Targets Ther202641978803PubTator, text miningPubMed
Comparative binding mechanisms of SND1 with MTDH and small-molecule inhibitors: insights from molecular dynamics simulations and free energy calculations.Phys Chem Chem Phys202641954452PubTator, text miningPubMed
Protein arginine methyltransferases in cancer: mechanisms, functions, and therapeutic opportunities.J Biomed Sci202641928257PubTator, text miningPubMed

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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