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VAPB: VAMP associated protein B and C
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Gene · 9217

Papers1,571

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 1,571

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TitleJournalYearPMIDFound bySource
Neuro-glial lipid imbalance in a Drosophila model of amyotrophic lateral sclerosis 8.Acta Neuropathol Commun202642760536PubTator, text miningPubMed
Sigma-1 Receptor Stimulation Rescues FTD/ALS Mutant TDP43-Induced Disruption of the VAPB-PTPIP51 ER-Mitochondria Tethering Proteins via Inhibition of GSK3β.Cells202642738830PubTator, text miningPubMed
Phosphorylation-dependent interaction between VAP proteins and INF2 influences ER morphology.Curr Biol202642710492PubTator, text miningPubMed
Glial ceramide orchestrates lipid homeostasis and age-dependent motor function.Dis Model Mech202642634871PubTator, text miningPubMed
Genetic profile of motor neuron disease in a multiregional Brazilian cohort: an 18-year real-world experience in 1,911 patients.Front Neurol202642621206PubTator, text miningPubMed
Impaired Endothelial Cell Cholesterol Metabolism Promotes Vascular Inflammation in Sleep Apnea.Circ Res202642375116PubTator, text miningPubMed
VAPB confers selective neuroprotection by driving autophagic degradation of pathogenic aggregates in ALS.Acta Neuropathol Commun202642210413PubTator, text miningPubMed
Clinical characterization and natural history of ALS8/VAPB p.Pro56Ser: upper motor neurone signs, survival, and functional milestones in 78 patients.Amyotroph Lateral Scler Frontotemporal Degener202642166520PubTator, text miningPubMed
Kv2-VAP interactions enhance presynaptic ER and mitochondrial calcium influx and the mobilization of vesicles from the reserve pool.bioRxiv202642146497PubTator, text miningPubMed
Quantitative FRET FLIM imaging reveals multiple interactions between proteins of the ESYT, ORP, and VAP families at the endoplasmic reticulum membrane.J Biol Chem202642134546PubTator, text miningPubMed
HIV-1 Tat-induced VAPB disruption initiates a cascade of organellar failures culminating in neuronal lipid accumulation.J Lipid Res202642092489PubTator, text miningPubMed
OSBPL10 Drives Lipophagy-Mediated Lipid Mobilization to Promote Pancreatic Ductal Adenocarcinoma Progression.Int J Biol Sci202642003919PubTator, text miningPubMed
BVDV NS5A promotes mitochondria-associated endoplasmic reticulum membrane (MAM) formation to enhance viral replication.Vet Microbiol202642001873PubTator, text miningPubMed
Ganoderic acid D alleviates vascular aging by restoring lysosomal function via stabilization of the VAPB-SNX25 tethering complex.Phytomedicine202641967234PubTator, text miningPubMed
Modeling the cell biology of PEX11β deficiency during human neurogenesis.bioRxiv202641756896PubTator, text miningPubMed
The Axon as a Self-Modifying Computational System: Autonomous Inference, Adaptive Propagation, and AI-Enabled Mechanistic Insight.Int J Mol Sci202641751965PubTator, text miningPubMed
Clinical characterization of the proximal lower-limb ALS phenotype: a retrospective cohort study.Amyotroph Lateral Scler Frontotemporal Degener202641733214PubTator, text miningPubMed
Novel extracellular vesicle release pathway facilitated by toxic superoxide dismutase 1 oligomers.Neurobiol Dis202641651252PubTator, text miningPubMed
Role of Oxysterol-Binding Protein Family in Cholesterol Metabolism and Cancer Progression: A Review.Med Sci Monit202641560326PubTator, text miningPubMed
Mitochondria-endoplasmic reticulum contact sites in hepatocytic senescence.Cell Mol Biol Lett202641521283PubTator, text miningPubMed

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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