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Gene · 9235

IL32: interleukin 32

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. IL32: interleukin 32. Genes, record 9235. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9235

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Gene

Symbol
IL32
HGNC
Name
interleukin 32
HGNC
NCBI Gene ID
9235
NCBI Gene
HGNC ID
HGNC:16830
HGNC
Ensembl
ENSG00000008517
NCBI Gene
Aliases
IL-32alpha, IL-32beta, IL-32delta, IL-32gamma, NK4, TAIF, TAIFa, TAIFb, TAIFc, TAIFd
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P24001Interleukin-322340Ensembl, GeneID, HGNC

Source UniProt

Patents120

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2025172069 A2025-11-2020P24001Espacenet
JP 2025172069 A2025-11-2024P24001Espacenet
JP 2025172069 A2025-11-2026P24001Espacenet
EP 4650780 A22025-11-1911426P24001Espacenet
US 12473363 B22025-11-18927P24001Espacenet
JP 2025147176 A2025-10-067063P24001Espacenet
JP 2025147176 A2025-10-067064P24001Espacenet
JP 2025147176 A2025-10-067065P24001Espacenet
JP 2025529142 A2025-09-046734P24001Espacenet
US 12371689 B22025-07-296734P24001Espacenet

1 to 10 of 120

See all 120 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,653

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIL32 papersNewest fiscal year
R01AI015614Pathogenesis of Fever in Man262025
P30CA046934University of Colorado Cancer Center Support Grant142025
UL1TR001863Yale Clinical and Translational Science Award122025
P30CA008748Cancer Center Support Grant102025
R01AG054324Role of IL-32 as a predictor and mediator of Premature Aging Phenotypes(PAP) in HIV infection.92025
R01AR040312CD1-restricted T-cell Responses in Skin92025
P30AR075043University of Michigan Skin Biology and Diseases Resource-based Center72025
P30CA016672Cancer Center Support Grant72025
R01AI022553Molecular Analysis of Host Immune Response in Leprosy72025
P30ES013508Center of Excellence in Environmental Toxicology52025

1 to 10 of 1,653Source NIH's project files

See all 1,653 nih grants

Papers3,054

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Advanced-stage cutaneous T-cell lymphomas show distinct immune profiles in erythroderma vs. tumor lesions.J Dermatol Sci202642810908PubTator, text miningPubMed
Mitochondrial DNA Released by Biliary Epithelial Cells Enhances Inflammation in Biliary Atresia Through the Cyclic GMP-AMP Synthase-Stimulator of Interferon Genes-Nuclear Factor-κB Pathway.Cell Mol Gastroenterol Hepatol202642785431PubTator, text miningPubMed
IL-32 drives PR3-dependent NET formation to promote portal vein tumor thrombosis and radioresistance in HCC.Transl Oncol202642767097PubTator, text miningPubMed
A Shared EGR1-IL-32-Macrophage Polarisation Signature in Rheumatoid Arthritis and Metabolic Dysfunction-Associated Steatotic Liver Disease.J Inflamm Res202642703413PubTator, text miningPubMed
Multimodal analysis of CD38 in T-cell Acute Lymphoblastic Leukemia Identifies Combinatorial Therapeutic Strategies.Blood202642685004PubTator, text miningPubMed
Dynamic integration of CXCL8 or CCL20 signaling with IL-15 or IL-32α reprograms human T-cell functional plasticity.Front Immunol202642682451PubTator, text miningPubMed
BRD4 contributes to the cytokine-induced acquisition of an IL-13RA2-positive inflammatory fibroblast phenotype.J Crohns Colitis202642635600PubTator, text miningPubMed
Stage-Specific Reduction of Serum IL-32 in Secondary Syphilis and Associations with Lipid Metabolism Parameters.Diagn Microbiol Infect Dis202642632155PubTator, text miningPubMed
Serum IL-32γ as a biomarker for remission assessment in systemic lupus erythematosus.Front Immunol202642620248PubTator, text miningPubMed
Single-cell profiling reveals IFI44L as a central regulator of immune dysregulation in high HIV viral load.Med Microbiol Immunol202642606736PubTator, text miningPubMed

1 to 10 of 3,054

See all 3,054 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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