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Gene · 926

CD8B: CD8 subunit beta

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CD8B: CD8 subunit beta. Genes, record 926. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/926

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Gene

Symbol
CD8B
HGNC
Name
CD8 subunit beta
HGNC
NCBI Gene ID
926
NCBI Gene
HGNC ID
HGNC:1707
HGNC
Ensembl
ENSG00000172116
NCBI Gene
Aliases
CD8B1, CD8beta, LEU2, LY3, LYT3, Ly-3, P37
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P10966T-cell surface glycoprotein CD8 beta chain2100Ensembl, GeneID, HGNC

Source UniProt

Patents197

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4831196 A22026-10-2815P10966Espacenet
EP 4825868 A12026-10-21257P10966Espacenet
WO 2026167079 A12026-08-132P10966Espacenet
WO 2026167093 A12026-08-1347P10966Espacenet
WO 2026167100 A12026-08-13114P10966Espacenet
EP 4750486 A22026-06-03131P10966Espacenet
US 12624087 B22026-05-1215P10966Espacenet
US 12612446 B22026-04-28456P10966Espacenet
JP 2024093056 A52026-02-27400P10966Espacenet
JP 2026504480 A2026-02-05220P10966Espacenet

1 to 10 of 197

See all 197 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,371

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCD8B papersNewest fiscal year
P30CA016672Cancer Center Support Grant252025
P51OD011092Support for National Primate Research Center242025
P30CA008748Cancer Center Support Grant162025
P50CA101942DF/HCC Kidney Cancer SPORE (supplement)102025
P30CA016042Cancer Center Support Grant92025
P51OD011132Emory National Primate Research Center92025
U19AI142742Human immune memory to COVID-19, vaccines, and respiratory pathogens82025
P30CA010815Consolidated Basic Cancer Research Program72025
P30CA047904Cancer Center Support Grant72025
P30DK042086Center for Interdisciplinary Study of Inflammatory Intestinal DIsorders (C-IID)72025

1 to 10 of 2,371Source NIH's project files

See all 2,371 nih grants

Papers3,225

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Virus-specific enhancement of the expression of CTLA-4 in T cells from target organs during early and late stages of PRRSV-1 infection with strains of different virulence.Vet Microbiol202642826489PubTator, text miningPubMed
Integrative single-cell and bulk transcriptomic profiling identify peripheral T-cell-associated candidate biomarkers in community-acquired pneumonia.Int J Med Sci202642694836PubTator, text miningPubMed
Tumor-Intrinsic DNA Damage Signaling Is Associated with MHC-I Expression and CD8 Cytotoxic T-Cell Engagement in Triple-Negative Breast Cancer.Curr Issues Mol Biol202642651843PubTator, text miningPubMed
Synergistic Profiling of Programmed Cell Death and Immune Responses Identifies a Novel Prognostic Index for Cervical Cancer.ACS Omega202642495322PubTator, text miningPubMed
Identification and validation of prognostic genes associated with clear cell renal cell carcinoma: based on public whole transcriptome sequencing datasets.Front Oncol202642488123PubTator, text miningPubMed
Herpesvirus of Turkeys (HVT) vaccine confers limited protection against the cellular changes induced by very virulent plus Marek's disease virus (vv + MDV) strains in commercial meat-type chickens.Vaccine202642447734PubTator, text miningPubMed
Single-cell analyses of liver and blood reveal distinct immune cell signatures of HBV-related HCC patients.Sci Rep202642393223PubTator, text miningPubMed
Genome-wide association study and predictors of neonatal blood cell traits in Hispanic newborns.Am J Hum Genet202642385717PubTator, text miningPubMed
Ill Fate of Rectal Mucinous Adenocarcinoma: A Defect in Immunosurveillance or a Mucin Coating Effect?-The IMMUNOREACT 20 Study.Cancers (Basel)202642352477PubTator, text miningPubMed
Intracellular CD3 and surface CD8β distinguish activated human T cells from natural killer cells after αCD3/αCD28 stimulation.J Immunol Methods202642276454PubTator, text miningPubMed

1 to 10 of 3,225

See all 3,225 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/926

GET https://conductscience.org/api/genes/v1/926/patents?page=2