Gene · 926
CD8B: CD8 subunit beta
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CD8B: CD8 subunit beta. Genes, record 926. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/926
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P10966 | T-cell surface glycoprotein CD8 beta chain | 210 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents197
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4831196 A2 | 2026-10-28 | 15 | P10966 | Espacenet |
| EP 4825868 A1 | 2026-10-21 | 257 | P10966 | Espacenet |
| WO 2026167079 A1 | 2026-08-13 | 2 | P10966 | Espacenet |
| WO 2026167093 A1 | 2026-08-13 | 47 | P10966 | Espacenet |
| WO 2026167100 A1 | 2026-08-13 | 114 | P10966 | Espacenet |
| EP 4750486 A2 | 2026-06-03 | 131 | P10966 | Espacenet |
| US 12624087 B2 | 2026-05-12 | 15 | P10966 | Espacenet |
| US 12612446 B2 | 2026-04-28 | 456 | P10966 | Espacenet |
| JP 2024093056 A5 | 2026-02-27 | 400 | P10966 | Espacenet |
| JP 2026504480 A | 2026-02-05 | 220 | P10966 | Espacenet |
1 to 10 of 197
See all 197 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,371
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CD8B papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 25 | 2025 |
| P51OD011092 | Support for National Primate Research Center | 24 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 16 | 2025 |
| P50CA101942 | DF/HCC Kidney Cancer SPORE (supplement) | 10 | 2025 |
| P30CA016042 | Cancer Center Support Grant | 9 | 2025 |
| P51OD011132 | Emory National Primate Research Center | 9 | 2025 |
| U19AI142742 | Human immune memory to COVID-19, vaccines, and respiratory pathogens | 8 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 7 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 7 | 2025 |
| P30DK042086 | Center for Interdisciplinary Study of Inflammatory Intestinal DIsorders (C-IID) | 7 | 2025 |
1 to 10 of 2,371Source NIH's project files
See all 2,371 nih grantsPapers3,225
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Virus-specific enhancement of the expression of CTLA-4 in T cells from target organs during early and late stages of PRRSV-1 infection with strains of different virulence. | Vet Microbiol | 2026 | 42826489 | PubTator, text mining | PubMed |
| Integrative single-cell and bulk transcriptomic profiling identify peripheral T-cell-associated candidate biomarkers in community-acquired pneumonia. | Int J Med Sci | 2026 | 42694836 | PubTator, text mining | PubMed |
| Tumor-Intrinsic DNA Damage Signaling Is Associated with MHC-I Expression and CD8 Cytotoxic T-Cell Engagement in Triple-Negative Breast Cancer. | Curr Issues Mol Biol | 2026 | 42651843 | PubTator, text mining | PubMed |
| Synergistic Profiling of Programmed Cell Death and Immune Responses Identifies a Novel Prognostic Index for Cervical Cancer. | ACS Omega | 2026 | 42495322 | PubTator, text mining | PubMed |
| Identification and validation of prognostic genes associated with clear cell renal cell carcinoma: based on public whole transcriptome sequencing datasets. | Front Oncol | 2026 | 42488123 | PubTator, text mining | PubMed |
| Herpesvirus of Turkeys (HVT) vaccine confers limited protection against the cellular changes induced by very virulent plus Marek's disease virus (vv + MDV) strains in commercial meat-type chickens. | Vaccine | 2026 | 42447734 | PubTator, text mining | PubMed |
| Single-cell analyses of liver and blood reveal distinct immune cell signatures of HBV-related HCC patients. | Sci Rep | 2026 | 42393223 | PubTator, text mining | PubMed |
| Genome-wide association study and predictors of neonatal blood cell traits in Hispanic newborns. | Am J Hum Genet | 2026 | 42385717 | PubTator, text mining | PubMed |
| Ill Fate of Rectal Mucinous Adenocarcinoma: A Defect in Immunosurveillance or a Mucin Coating Effect?-The IMMUNOREACT 20 Study. | Cancers (Basel) | 2026 | 42352477 | PubTator, text mining | PubMed |
| Intracellular CD3 and surface CD8β distinguish activated human T cells from natural killer cells after αCD3/αCD28 stimulation. | J Immunol Methods | 2026 | 42276454 | PubTator, text mining | PubMed |
1 to 10 of 3,225
See all 3,225 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/926
GET https://conductscience.org/api/genes/v1/926/patents?page=2