Gene · 9271
PIWIL1: piwi like RNA-mediated gene silencing 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PIWIL1: piwi like RNA-mediated gene silencing 1. Genes, record 9271. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9271
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q96J94 | Piwi-like protein 1 | 861 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents44
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 58084 | Q96J94 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 813 | Q96J94 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 813 | Q96J94 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 33491 | Q96J94 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 33497 | Q96J94 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 33491 | Q96J94 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 33497 | Q96J94 | Espacenet |
| KR 1020240156643 A | 2024-10-30 | 350 | Q96J94 | Espacenet |
| JP 2024097033 A | 2024-07-17 | 79 | Q96J94 | Espacenet |
| US 11666644 B2 | 2023-06-06 | 79 | Q96J94 | Espacenet |
1 to 10 of 44
See all 44 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,251
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PIWIL1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA045508 | CSHL Cancer Center Support Grant | 10 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P40OD010440 | Caenorhabditis Genetics Center | 6 | 2025 |
| P01CA013106 | Targeting Transcription and Splicing in Cancer | 5 | 2025 |
| P50HD096723 | Genetics of Male Infertility: Accelerating the pace of discovery | 5 | 2025 |
| R35GM127090 | Structural and Mechanistic basis for RNA Silencing | 5 | 2025 |
| ZIADK075111 | PIWI proteins and PIWI-interacting small RNAs guard the genomic integrity of germ cells | 5 | 2025 |
| R01GM083300 | Selective regulatory and biogenesis mechanisms for microRNAs | 4 | 2025 |
| R01HD078641 | Genomics of spermatogenic impairment | 4 | 2025 |
| P01HL116263 | HDL Function in Human Disease | 3 | 2025 |
1 to 10 of 1,251Source NIH's project files
See all 1,251 nih grantsPapers2,375
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Dual origins for neural cells during development of the Clytia planula larva. | Development | 2026 | 42757688 | PubTator, text mining | PubMed |
| Pathogenic Variants in PET Complex Encoding Genes TDRD12 and EXD1 Impair piRNA Biogenesis and Cause Male Infertility. | Hum Mutat | 2026 | 42631111 | PubTator, text mining | PubMed |
| Dysregulation of piRNA biogenesis-associated proteins in cancer: mechanisms, evidence, and translational constraints. | Front Mol Biosci | 2026 | 42625859 | PubTator, text mining | PubMed |
| PIWI-piRNA Axis in Epilepsy: Bridging Epigenetic Regulation, Neuroinflammation, and Neuronal Excitability. | Mol Neurobiol | 2026 | 42572073 | PubTator, text mining | PubMed |
| The emerging roles of small nucleolar RNAs, piwi-interacting RNAs, tRNA-derived small RNAs, and circular RNAs in the regulation of cardiac hypertrophy, ischemic heart disease, and heart failure. | Genes Dis | 2026 | 42502482 | PubTator, text mining | PubMed |
| Dibromoacetic acid impairs spermatogenesis: integrative evidence from human epidemiology, network toxicology, and mechanistic validation. | Environ Int | 2026 | 42468183 | PubTator, text mining | PubMed |
| Inverse co-variation of circulating PIWIL2 and PIWIL4 in gastric adenocarcinoma: an exploratory ELISA-based study. | Clin Proteomics | 2026 | 42402549 | PubTator, text mining | PubMed |
| piR-hsa-8111406 promotes proliferation and serves as a novel biomarker for early detection of ovarian cancer: a multi-center retrospective study. | Int J Gynecol Cancer | 2026 | 42391800 | PubTator, text mining | PubMed |
| piR-LGBM: A Sparse Autoencoder-Enhanced Gradient Boosting Framework to Uncover Disease-Associated piRNAs. | OMICS | 2026 | 42267858 | PubTator, text mining | PubMed |
| Landscape and biogenesis of piRNAs in HBV-associated hepatocarcinogenesis: from repetitive elements to oncogenic circuits. | Discov Oncol | 2026 | 42258089 | PubTator, text mining | PubMed |
1 to 10 of 2,375
See all 2,375 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/9271
GET https://conductscience.org/api/genes/v1/9271/patents?page=2