ConductScience.org, home

Gene · 9290

GPR55: G protein-coupled receptor 55

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. GPR55: G protein-coupled receptor 55. Genes, record 9290. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9290

On this page

Gene

Symbol
GPR55
HGNC
Name
G protein-coupled receptor 55
HGNC
NCBI Gene ID
9290
NCBI Gene
HGNC ID
HGNC:4511
HGNC
Ensembl
ENSG00000135898
NCBI Gene
Aliases
LPIR1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9Y2T6G protein-coupled receptor 553196Ensembl, GeneID, HGNC

Source UniProt

Patents42

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1447061Q9Y2T6Espacenet
JP 2026004568 A2026-01-1447062Q9Y2T6Espacenet
JP 2026004568 A2026-01-1447064Q9Y2T6Espacenet
EP 4641201 A22025-10-2911255Q9Y2T6Espacenet
JP 2025529142 A2025-09-041833Q9Y2T6Espacenet
US 12371689 B22025-07-291833Q9Y2T6Espacenet
JP 2025517969 A2025-06-1211255Q9Y2T6Espacenet
JP 2023153821 A2023-10-1847Q9Y2T6Espacenet
US 11446398 B22022-09-2033563Q9Y2T6Espacenet
US 11446398 B22022-09-2033564Q9Y2T6Espacenet

1 to 10 of 42

See all 42 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants672

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGPR55 papersNewest fiscal year
T32DA007237Neurobiology of Addiction Training Program52025
ZIAAA000375Mechanism of oxidative/nitrosative stress and inflammation-induced tissue injury52025
UL1TR001863Yale Clinical and Translational Science Award42025
ZIAAA000351Endocannabinoids and the Control Of Behavior and Cardiovascular Function42025
P01DA009158Endocannabinoid Active Sites as Therapeutic Targets32025
P30AI161943Texas Developmental Center for AIDS Research32025
T32DA007209Human Behavioral Pharmacology of Substance Abuse32025
ZIAAA000350Endocannabinoids And Energy Homeostasis32025
P30AG066511Goizueta Alzheimer's Disease Research Center22025
P30CA016086Cancer Center Support Grant22025

1 to 10 of 672Source NIH's project files

See all 672 nih grants

Papers1,426

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Depression of synaptic outputs by reduction of Ca2+ influx, but not RRP vesicles, becomes evident upon CB2R hyper-expression at cerebellar Purkinje cell terminals.Front Mol Neurosci202642661811PubTator, text miningPubMed
The Potential of Cannabidiol for the Treatment of Psychosis: Endocannabinoid Regulation of Serotonergic Neurotransmission via Serotonin 5-HT1A/2A Receptors.Neurochem Res202642658346PubTator, text miningPubMed
Beyond inflammation: Cannabinoid receptors as metabolic checkpoints in glial reprogramming during neurodegeneration.Int Immunopharmacol202642624021PubTator, text miningPubMed
Emerging roles of cannabinoid pathways in renal injury and repair.Front Pharmacol202642572649PubTator, text miningPubMed
GPR55 and PINK1 as emerging therapeutic targets in Glioma: insights into their modulation by phytochemicals and plant extracts.Front Pharmacol202642568689PubTator, text miningPubMed
An agonist of the cannabinoid-sensing G-protein coupled receptor 55 promotes wound healing and protects against UVB-induced keratinocyte damage.Tissue Barriers202642555531PubTator, text miningPubMed
Cannabinoid receptor-mediated modulation of the gut-brain axis under chronic stress: Neuroinflammatory mechanisms, microbial metabolites, and sexual dimorphism.Prog Neuropsychopharmacol Biol Psychiatry202642526737PubTator, text miningPubMed
Cannabidiol and epilepsy: therapeutic, mechanistic and clinical significance.Seizure202642424869PubTator, text miningPubMed
GPR55 negatively regulates CD8+ intraepithelial lymphocyte migration dynamics in oral lichen planus.J Mol Histol202642418020PubTator, text miningPubMed
LPI alleviates Alzheimer's disease pathology via the GPR55 receptor.Neuroscience202642362040PubTator, text miningPubMed

1 to 10 of 1,426

See all 1,426 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9290

GET https://conductscience.org/api/genes/v1/9290/patents?page=2