Gene · 9353
SLIT2: slit guidance ligand 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SLIT2: slit guidance ligand 2. Genes, record 9353. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9353
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O94813 | Slit homolog 2 protein | 1,529 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents74
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 63722 | O94813 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 14642 | O94813 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 17202 | O94813 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 12489 | O94813 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 4340 | O94813 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7747 | O94813 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 4340 | O94813 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7747 | O94813 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 17202 | O94813 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 14642 | O94813 | Espacenet |
1 to 10 of 74
See all 74 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,536
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SLIT2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA021765 | Cancer Center Support Grant (CCSG) | 5 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 4 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 4 | 2025 |
| P30EY007003 | University of Michigan Vision Research Center | 4 | 2025 |
| R01HL125811 | Slit2-ROBO signaling in pericytes and myeloid cells controls vascular development and ocular neovascular disease | 4 | 2025 |
| T32CA009592 | Microenvironmental Influences in Cancer | 4 | 2025 |
| K12CA090628 | Paul Calabresi Program in Clinical/Translational Research at Mayo Clinic | 3 | 2025 |
| P20GM103440 | Nevada IDeA Networks of Biomedical Research Excellence (INBRE) | 3 | 2025 |
1 to 10 of 1,536Source NIH's project files
See all 1,536 nih grantsPapers2,094
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| SLIT2 modulates leukaemic cell proliferation and stromal support in acute myeloid leukaemia models. | Br J Haematol | 2026 | 42786580 | PubTator, text mining | PubMed |
| Gbx2 and Robo receptors control amacrine cell dendrite stratification in the mammalian retina. | Dev Biol | 2026 | 42716364 | PubTator, text mining | PubMed |
| Druggable tumor-nerve-immune circuits in cancer pain: Model systems, human translatability and therapeutic paradoxes. | Pharmacol Res | 2026 | 42716238 | PubTator, text mining | PubMed |
| The nociceptor-CGRP-lactate axis in cancer immune escape: Linking neural signaling, immunometabolism, and immunotherapy resistance. | Pharmacol Res | 2026 | 42702340 | PubTator, text mining | PubMed |
| Exploring the protective potential of remote ischemic conditioning-induced miRNAs in stroke. | Neuroscience | 2026 | 42603607 | PubTator, text mining | PubMed |
| Impaired adipogenesis and lipid storage capacity in subcutaneous adipose tissue of patients with PMOS. | JCI Insight | 2026 | 42579798 | PubTator, text mining | PubMed |
| SLIT2 and ANGPTL3 as putative mediators linking obesity to atrial fibrillation: A Mendelian randomization study. | Medicine (Baltimore) | 2026 | 42410793 | PubTator, text mining | PubMed |
| SLIT-ROBO Signaling in Diabetes: A Dual Regulator of Angiogenesis and Vascular Dysfunction. | Compr Physiol | 2026 | 42397141 | PubTator, text mining | PubMed |
| A novel circSLIT2-encoded SLIT2 isoform suppresses neural invasion in gastric cancer. | Oncogene | 2026 | 42362756 | PubTator, text mining | PubMed |
| SLIT2 and ROBO-axis inhibitors for the treatment of cancer: a patent review (2020-2026). | Expert Opin Ther Pat | 2026 | 42311159 | PubTator, text mining | PubMed |
1 to 10 of 2,094
See all 2,094 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/9353
GET https://conductscience.org/api/genes/v1/9353/patents?page=2