Gene · 9378
NRXN1: neurexin 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NRXN1: neurexin 1. Genes, record 9378. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9378
On this page
Gene
Proteins2
Reviewed human proteins whose Swiss-Prot entry states the gene.
Patents61
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12636345 B2 | 2026-05-26 | 14 | P58400 | Espacenet |
| US 12636345 B2 | 2026-05-26 | 16 | Q9ULB1 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 55304 | Q9ULB1 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 11800 | Q9ULB1 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 12550 | Q9ULB1 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 12782 | P58400 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 9559 | Q9ULB1 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 9573 | P58400 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2912 | Q9ULB1 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7182 | Q9ULB1 | Espacenet |
1 to 10 of 61
See all 61 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,307
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NRXN1 papers | Newest fiscal year |
|---|---|---|---|
| R25MH077823 | Research Education for Future Physician-Scientists in Child Psychiatry | 9 | 2025 |
| U24AG021886 | National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD) | 7 | 2025 |
| R01MH101221 | Rare Mutations and Autism Spectrum Disorders | 6 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 6 | 2025 |
| R01MH074090 | Gene Dosage Imbalance in Neurodevelopmental Disorders | 5 | 2025 |
| P30ES010126 | UNC Center for Environmental Health and Susceptibility | 4 | 2025 |
| P30ES013508 | Center of Excellence in Environmental Toxicology | 4 | 2025 |
| R01HD081256 | Clinical Diagnostic Sequencing of Structural Variation | 4 | 2025 |
| R01MH077303 | Synaptic Organizers: Dynamic Regulation of Trans-synaptic Bridges | 4 | 2025 |
| T32HG000035 | Interdisciplinary Training in Genome Sciences | 4 | 2025 |
1 to 10 of 2,307Source NIH's project files
See all 2,307 nih grantsPapers2,134
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Neurexin mediates neuropeptide release from cholinergic motor neurons through dense-core vesicle localization. | bioRxiv | 2026 | 42818522 | PubTator, text mining | PubMed |
| Chromosomal Microarray Diagnostic Yield and Copy Number Variants in a Clinically Well-Characterized Cohort with Nonsyndromic Autism Spectrum Disorder from Southern Brazil. | Diagnostics (Basel) | 2026 | 42793732 | PubTator, text mining | PubMed |
| In vivo dissection of human NRXN1 isoforms reveals gain-of-function pathogenicity of schizophrenia-associated 3' deletions. | Hum Mol Genet | 2026 | 42696786 | PubTator, text mining | PubMed |
| Thalamic NRXN1-mediated input to human cortical progenitors drives excitatory neurogenesis. | Science | 2026 | 42691176 | PubTator, text mining | PubMed |
| Prenatal diagnosis of a familial 2p16.3 deletion encompassing NRXN1 associated with no apparently phenotypic abnormality in the family carrier members. | Taiwan J Obstet Gynecol | 2026 | 42642129 | PubTator, text mining | PubMed |
| Pleiotrophin regulates presynaptic assembly and function through heparan sulfate-dependent binding to neurexin1. | Cell Rep | 2026 | 42585021 | PubTator, text mining | PubMed |
| Clinical Phenotypes Associated with NRXN1 Deletions in Five Children with Autism Spectrum Disorder in Oman. | Sultan Qaboos Univ Med J | 2026 | 42549207 | PubTator, text mining | PubMed |
| Intrafamilial Variability in NRXN1-Associated Neurodevelopmental Disorders: Clinical and Genetic Insights from a Family Case Study with Literature Review. | Int J Mol Sci | 2026 | 42511584 | PubTator, text mining | PubMed |
| Genome-Wide and Rare Variant Association Studies of Amblyopia in Admixed American and African Ancestry Groups. | Ophthalmology | 2026 | 42508771 | PubTator, text mining | PubMed |
G-protein coupled receptor, signal and signal-transduction related transcript mapping in nigral volume and pigmented neurons reveals a potential deficit of nigral feedback signals associated with Parkinson's disease. | PLoS One | 2026 | 42497285 | PubTator, text mining | PubMed |
1 to 10 of 2,134
See all 2,134 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/9378
GET https://conductscience.org/api/genes/v1/9378/patents?page=2