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CD27: CD27 molecule

1 protein, 153 patents, 1 drug, 15 trials, 8,518 NIH grants and 18,731 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCD27HGNC
NameCD27 moleculeHGNC
NCBI Gene ID939NCBI Gene
HGNC IDHGNC:11922HGNC
EnsemblENSG00000139193NCBI Gene
AliasesS152, S152. LPFS2, T14, TNFRSF7, Tp55NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P26842CD27 antigen2605Ensembl, GeneID, HGNCUniProt

Patents 153

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4801945 A22026-09-091P26842Espacenet
EP 4754236 A12026-06-10188P26842Espacenet
JP 2026082951 A2026-05-1921P26842Espacenet
JP 2026516158 A2026-05-197P26842Espacenet
EP 4709396 A12026-03-187P26842Espacenet
EP 4705273 A22026-03-11316P26842Espacenet
JP 2026500896 A2026-01-0919P26842Espacenet
WO 2025262045 A12025-12-2626P26842Espacenet
WO 2025245063 A12025-11-27246P26842Espacenet
JP 2025172069 A2025-11-20340P26842Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
VARLILUMABCHEMBL3137347CD27 antigen agonistAGONISTChEMBL

Trials 15

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT04941287VARLILUMABPHASE22025-05-23ClinicalTrials.gov
NCT04081688VARLILUMABPHASE12023-06-02ClinicalTrials.gov
NCT03688178VARLILUMABPHASE2ClinicalTrials.gov
NCT03617328VARLILUMABPHASE1/PHASE2ClinicalTrials.gov
NCT03307746VARLILUMABPHASE1/PHASE2ClinicalTrials.gov
NCT03038672VARLILUMABPHASE22024-10-16ClinicalTrials.gov
NCT02924038VARLILUMABPHASE12024-06-14ClinicalTrials.gov
NCT02543645VARLILUMABPHASE1ClinicalTrials.gov
NCT02413827VARLILUMABPHASE1/PHASE2ClinicalTrials.gov
NCT02386111VARLILUMABPHASE1ClinicalTrials.gov

NIH grants 8518

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant1072,025NIH's project files
P30CA016672Cancer Center Support Grant1062,025NIH's project files
P30AI027763UCSF-Bay Area Center for AIDS Research732,025NIH's project files
U19AI057229Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitro682,025NIH's project files
U19AI057266Vaccine and Infection Induced Immunity in the Young and Aged552,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award512,025NIH's project files
P51OD011132Emory National Primate Research Center502,025NIH's project files
U19AI082630Durable Alteration of the Human Immune system after Infection or Immunotherapy432,025NIH's project files
P30CA016520Abramson Cancer Center Support Grant382,025NIH's project files
U19AI110483Regulation of B cell Responses in SLE and Other Autoimmune Diseases382,025NIH's project files

Papers 18731

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818546PubTator, text miningPubMed
42814322PubTator, text miningPubMed
42812140PubTator, text miningPubMed
42810908PubTator, text miningPubMed
42804348PubTator, text miningPubMed
42793168PubTator, text miningPubMed
42786841PubTator, text miningPubMed
42776797PubTator, text miningPubMed
42774868PubTator, text miningPubMed
42773823PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license