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Gene · 9402

GRAP2: GRB2 related adaptor protein 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GRAP2: GRB2 related adaptor protein 2. Genes, record 9402. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9402

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Gene

Symbol
GRAP2
HGNC
Name
GRB2 related adaptor protein 2
HGNC
NCBI Gene ID
9402
NCBI Gene
HGNC ID
HGNC:4563
HGNC
Ensembl
ENSG00000100351
NCBI Gene
Aliases
GADS, GRAP-2, GRB2L, GRBLG, GRID, GRPL, GrbX, Grf40, Mona, P38
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O75791GRB2-related adapter protein 23301Ensembl, GeneID, HGNC

Source UniProt

Patents29

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1448237O75791Espacenet
JP 2026004568 A2026-01-1448239O75791Espacenet
EP 4661970 A12025-12-1762149O75791Espacenet
EP 4484957 A12025-01-0114O75791Espacenet
WO 2023162878 A2023-08-3114O75791Espacenet
US 11446398 B22022-09-2036316O75791Espacenet
US 11446398 B22022-09-2036317O75791Espacenet
JP 2022524081 A2022-04-27139287O75791Espacenet
JP 2022524081 A2022-04-27139288O75791Espacenet
US 11078247 B22021-08-034701O75791Espacenet

1 to 10 of 29

See all 29 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants993

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGRAP2 papersNewest fiscal year
ZIABC010304Biochemical Basis of T Cell Activation122025
P01AI091580Defining the Unique Properties of the Distinct Signaling Machinery Used by the TCR82025
P30CA008748Cancer Center Support Grant62025
P30CA076292Moffitt Cancer Center Support Grant52025
P30CA086862Cancer Center Support Grant52025
T32AI007485Predoctoral Training Program in Immunology42025
T32DA007209Human Behavioral Pharmacology of Substance Abuse32025
UL1TR001863Yale Clinical and Translational Science Award32025
ZICBC010978Confocal Core for the Laboratory of Cellular and Molecular Biology32025
KL2TR002317Institutional Career Development Core22025

1 to 10 of 993Source NIH's project files

See all 993 nih grants

Papers1,586

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Blood parameters and whole-blood transcriptomics associated with immune-related adverse events in metastatic renal cell carcinoma during nivolumab plus ipilimumab.Sci Rep202642026114PubTator, text miningPubMed
Machine learning model based on plasma proteomics for the identification of Parkinson's disease.Brain202642015416PubTator, text miningPubMed
Generalizable, high-throughput image analysis of subcellular structures using dispersion indices.iScience202641993690PubTator, text miningPubMed
ZBTB7A promotes malignant phenotypes in ovarian cancer through transcriptional activation of CRLF1.Oncol Rep202641891980PubTator, text miningPubMed
KR-62980, a novel PPARγ agonist, inhibits collagen-induced platelet activation and thrombus formation by regulating the GPVI signaling pathway.Biochem Pharmacol202641871717PubTator, text miningPubMed
Placing purines in precision medicine: Targeting a metabolic reliance in KRAS-mutant tumors.iScience202641767257PubTator, text miningPubMed
Understanding diverse subjectivities of medical students in seeking composite role models: A Q-methodology study.PLoS One202641758802PubTator, text miningPubMed
Chromatin Engagement and Transcriptional Activity of the ZNF217 Exon 4-Skipping Isoform Are Associated with Breast Cancer Aggressiveness and Bone Metastasis.Cancers (Basel)202641749916PubTator, text miningPubMed
T Cell Receptor Co-Stimulation Through Magnetogenetic Tools: A Platform for Wireless Rewiring of Cellular Signaling.ACS Omega202641726657PubTator, text miningPubMed
Optimal GRID-HAM-D7 cut-off scores for defining remission in older Thai adults with depression.Front Psychiatry202641696477PubTator, text miningPubMed

1 to 10 of 1,586

See all 1,586 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9402

GET https://conductscience.org/api/genes/v1/9402/patents?page=2