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Gene · 9415

FADS2: fatty acid desaturase 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FADS2: fatty acid desaturase 2. Genes, record 9415. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9415

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Gene

Symbol
FADS2
HGNC
Name
fatty acid desaturase 2
HGNC
NCBI Gene ID
9415
NCBI Gene
HGNC ID
HGNC:3575
HGNC
Ensembl
ENSG00000134824
NCBI Gene
Aliases
D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O95864Acyl-CoA 6-desaturase4440Ensembl, GeneID, HGNC

Source UniProt

Patents66

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1445940O95864Espacenet
EP 4650780 A22025-11-193034O95864Espacenet
EP 4641202 A22025-10-29147O95864Espacenet
JP 2025529142 A2025-09-041473O95864Espacenet
US 12371689 B22025-07-291473O95864Espacenet
JP 2025517970 A2025-06-123034O95864Espacenet
KR 1020250017231 A2025-02-04147O95864Espacenet
US 11597953 B22023-03-0721O95864Espacenet
US 11446398 B22022-09-2030891O95864Espacenet
JP 2022524081 A2022-04-27133862O95864Espacenet

1 to 10 of 66

See all 66 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,008

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFADS2 papersNewest fiscal year
P30DK063491Diabetes Research Center (DRC)172025
P30DK020572Michigan Diabetes Research Center (MDRC)122025
UL1TR001881UCLA Clinical and Translational Science Institute82025
P30DK040561Boston Area Nutrition Obesity Research Center (NORC)72025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital72025
P30DK089503Michigan Nutrition Obesity Research Center72025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal72025
U01CA167551Colon Cancer Family Registry Cohort72025
P30CA008748Cancer Center Support Grant62025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)62025

1 to 10 of 2,008Source NIH's project files

See all 2,008 nih grants

Papers3,202

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Associations among FADS1/2 expression, long-chain polyunsaturated fatty acid metabolism, and adipokines in colostrum and mature human milk.J Dairy Sci202642754031PubTator, text miningPubMed
Evolutionary conservation analysis reveals a primordial function of STING as a regulator of lipid metabolism via FADS2.Nat Commun202642733078PubTator, text miningPubMed
From gut to pancreas: Shared genetic susceptibility and biological convergence in acute pancreatitis and Crohn's disease.PLoS One202642726709PubTator, text miningPubMed
Ethnicity and antenatal maternal anxiety: associations with the human milk lipidome in a multi-ethnic Asian cohort.Front Nutr202642694327PubTator, text miningPubMed
Effect of a 6-month low-carbohydrate diet on the circulating fatty acid composition in patients with type 2 diabetes: a secondary analysis of an open-label randomized controlled trial.Am J Clin Nutr202642680257PubTator, text miningPubMed
Atherogenic Index of Plasma in Relation to Angiographic Coronary Artery Disease Severity, Plasma Fatty Acid Composition, and Estimated Desaturase Activity: A Cross-Sectional Study.Metabolites202642646296PubTator, text miningPubMed
Effects of α-Synuclein on the Lipid Phenotype of SZ95 Human Sebocytes: A Preliminary Study in the Context of Parkinson's Disease.Cells202642645231PubTator, text miningPubMed
Genetic Markers of Early Skeletal Muscle Loss in Adolescent and Young Adult Cancer Patients Treated with Anthracyclines.J Adolesc Young Adult Oncol202642635325PubTator, text miningPubMed
Global Change Reshapes Biosynthesis of LC-PUFA in Northern Lake Food Webs.Glob Chang Biol202642634596PubTator, text miningPubMed
Are sustainable plant-based diets suitable for all? A nutrigenetic perspective.Nutr Health202642593171PubTator, text miningPubMed

1 to 10 of 3,202

See all 3,202 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9415

GET https://conductscience.org/api/genes/v1/9415/patents?page=2