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CD86: CD86 molecule

1 protein, 205 patents, 2 drugs, 172 trials, 11,779 NIH grants and 31,350 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCD86HGNC
NameCD86 moleculeHGNC
NCBI Gene ID942NCBI Gene
HGNC IDHGNC:1705HGNC
EnsemblENSG00000114013NCBI Gene
AliasesB7-2, B7.2, B70, BU63, CD28LG2, CD86 v6, FUN-1, LAB72NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P42081T-lymphocyte activation antigen CD863297Ensembl, GeneID, HGNCUniProt

Patents 205

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4831196 A22026-10-282P42081Espacenet
EP 4824105 A12026-10-21428P42081Espacenet
WO 2026143065 A12026-07-0274P42081Espacenet
WO 2026143070 A12026-07-02132P42081Espacenet
US 12624087 B22026-05-122P42081Espacenet
US 12612446 B22026-04-28444P42081Espacenet
JP 2026004568 A2026-01-1440638P42081Espacenet
JP 2026500896 A2026-01-0913P42081Espacenet
JP 2026500897 A2026-01-0913P42081Espacenet
JP 2025539875 A2025-12-091P42081Espacenet

Drugs 2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ABATACEPTCHEMBL1201823T-lymphocyte activation antigen CD86 inhibitorINHIBITORChEMBL
BELATACEPTCHEMBL1742990T-lymphocyte activation antigen CD86 inhibitorINHIBITORChEMBL

Trials 172

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07599176ABATACEPTPHASE1/PHASE2ClinicalTrials.gov
NCT07388563ABATACEPTPHASE1ClinicalTrials.gov
NCT07238712ABATACEPTPHASE2ClinicalTrials.gov
NCT07161999ABATACEPTPHASE2/PHASE3ClinicalTrials.gov
NCT06654882ABATACEPTPHASE3ClinicalTrials.gov
NCT06418529ABATACEPT2025-07-31ClinicalTrials.gov
NCT06307808BELATACEPTClinicalTrials.gov
NCT06307301ABATACEPTPHASE1ClinicalTrials.gov
NCT06145282ABATACEPTPHASE1/PHASE2ClinicalTrials.gov
NCT06055608BELATACEPTPHASE2ClinicalTrials.gov

NIH grants 11779

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant1162,025NIH's project files
P30CA008748Cancer Center Support Grant1072,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award472,025NIH's project files
P30CA047904Cancer Center Support Grant422,025NIH's project files
P30CA006973Regional Oncology Research Center392,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program322,025NIH's project files
P01CA065493Off-the-Shelf Immune Effector Cells for Hematological Malignancies312,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant312,025NIH's project files
P30CA016359Cancer Center Support Grant282,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant282,025NIH's project files

Papers 31350

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827008PubTator, text miningPubMed
42826780PubTator, text miningPubMed
42825120PubTator, text miningPubMed
42817441PubTator, text miningPubMed
42802264PubTator, text miningPubMed
42796734PubTator, text miningPubMed
42796480PubTator, text miningPubMed
42794643PubTator, text miningPubMed
42792729PubTator, text miningPubMed
42791421PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license