ConductScience.org, home

Gene · 9436

NCR2: natural cytotoxicity triggering receptor 2

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. NCR2: natural cytotoxicity triggering receptor 2. Genes, record 9436. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9436

On this page

Gene

Symbol
NCR2
HGNC
Name
natural cytotoxicity triggering receptor 2
HGNC
NCBI Gene ID
9436
NCBI Gene
HGNC ID
HGNC:6732
HGNC
Ensembl
ENSG00000096264
NCBI Gene
Aliases
CD336, LY95, NK-p44, NKP44, dJ149M18.1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O95944Natural cytotoxicity triggering receptor 22761Ensembl, GeneID, HGNC

Source UniProt

Patents52

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4754241 A12026-06-1046O95944Espacenet
JP 2026004568 A2026-01-1455070O95944Espacenet
JP 2025541179 A2025-12-18123O95944Espacenet
EP 4650780 A22025-11-199237O95944Espacenet
EP 4630459 A12025-10-15123O95944Espacenet
WO 2025191133 A12025-09-1851O95944Espacenet
WO 2025191136 A12025-09-1851O95944Espacenet
JP 2025529142 A2025-09-042789O95944Espacenet
US 12371689 B22025-07-292789O95944Espacenet
JP 2025517970 A2025-06-129237O95944Espacenet

1 to 10 of 52

See all 52 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,617

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNCR2 papersNewest fiscal year
P01CA065493Off-the-Shelf Immune Effector Cells for Hematological Malignancies242025
P30CA016672Cancer Center Support Grant222025
P01CA111412NK cells, their receptors and cancer therapy192025
P30CA006927Comprehensive Cancer Center Program at Fox Chase192025
P30CA016058Cancer Center Support Grant172025
P01CA163205Circumventing Barriers to Effective Oncolytic Virotherapy of Malignant Gliomas122025
P30CA021765Cancer Center Support Grant (CCSG)112025
P30CA008748Cancer Center Support Grant102025
P30CA077598Cancer Center Support Grant102025
P30CA091842Cancer Center Support Grant102025

1 to 10 of 1,617Source NIH's project files

See all 1,617 nih grants

Papers3,322

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Neutrophil extracellular traps promote liver metastasis by impairing NK cell-dependent tumor surveillance via CCDC25.Nat Commun202642716934PubTator, text miningPubMed
Interleukin-37 Enhances Liver NK Cell Cytotoxicity and Improves Recurrence-Free Survival in Hepatocellular Carcinoma Patients.J Hepatobiliary Pancreat Sci202642695172PubTator, text miningPubMed
Friend or foe: divergent immunomodulatory effects of metabolites derived from the virucidal zinc finger inhibitor SAMT-247.Front Immunol202642694244PubTator, text miningPubMed
NKp44 recognition of platelet-derived growth factor D enhances the cytolytic activity of natural killer cells.J Immunol202642522261PubTator, text miningPubMed
Coexpression of GITRL confers resistance to Treg cell-mediated immunosuppression to anti-CD19 CAR-NK cells.Front Immunol202642488650PubTator, text miningPubMed
Transcriptomic profiling of autoimmune hepatitis identifies TRAT1 as an in vitro negative regulator of NK cell effector functions.Front Immunol202642483202PubTator, text miningPubMed
Exploring the cognitive effects of arthritis: A Mendelian randomization study and cross-sectional analysis of NHANES data.Medicine (Baltimore)202642470017PubTator, text miningPubMed
Uncovering the cytogenetic hallmarks of resident and expanded natural killer cells from patients with acquired aplastic anemia.Sci Rep202642448949PubTator, text miningPubMed
Role of Innate Lymphoid Cells in Chronic Rhinosinusitis: Insights from Tissue and Peripheral Blood Flow Cytometric Analysis.Adv Respir Med202642345640PubTator, text miningPubMed
Sustained mucosal delivery of SAMT-247 via an intravaginal ring reduces the risk of SIVmac251 acquisition in vaccinated macaques.Cell Rep Med202642302793PubTator, text miningPubMed

1 to 10 of 3,322

See all 3,322 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9436

GET https://conductscience.org/api/genes/v1/9436/patents?page=2