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CD33: CD33 molecule

1 protein, 310 patents, 6 drugs, 128 trials, 7,225 NIH grants and 16,122 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCD33HGNC
NameCD33 moleculeHGNC
NCBI Gene ID945NCBI Gene
HGNC IDHGNC:1659HGNC
EnsemblENSG00000105383NCBI Gene
AliasesCD33rSiglec, FLJ00391, SIGLEC-3, SIGLEC3, p67NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P20138Myeloid cell surface antigen CD3336411Ensembl, GeneID, HGNCUniProt

Patents 310

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4794715 A12026-08-26174P20138Espacenet
EP 4795154 A12026-08-2627P20138Espacenet
JP 2026124818 A2026-07-311P20138Espacenet
EP 4777551 A12026-07-226P20138Espacenet
JP 2026515600 A2026-05-19176P20138Espacenet
JP 2026506554 A2026-02-251P20138Espacenet
JP 2026021386 A2026-02-101P20138Espacenet
EP 4684803 A12026-01-287P20138Espacenet
JP 2026009121 A2026-01-1997P20138Espacenet
WO 2026013158 A12026-01-15400P20138Espacenet

Drugs 6

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AVE-9633CHEMBL2109266Myeloid cell surface antigen CD33 binding agentBINDING AGENTChEMBL
GEMTUZUMABCHEMBL2108342Myeloid cell surface antigen CD33 binding agentBINDING AGENTChEMBL
GEMTUZUMAB OZOGAMICINCHEMBL1201506Myeloid cell surface antigen CD33 binding agentBINDING AGENTChEMBL
LINTUZUMABCHEMBL2109150Myeloid cell surface antigen CD33 otherOTHERChEMBL
M195CHEMBL2109267Myeloid cell surface antigen CD33 otherOTHERChEMBL
ONCOLYSIN MCHEMBL2109520Myeloid cell surface antigen CD33 binding agentBINDING AGENTChEMBL

Trials 128

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07422363LINTUZUMABPHASE1ClinicalTrials.gov
NCT07052994GEMTUZUMAB OZOGAMICINPHASE1ClinicalTrials.gov
NCT06917911GEMTUZUMAB OZOGAMICINPHASE2ClinicalTrials.gov
NCT06802523LINTUZUMABPHASE1ClinicalTrials.gov
NCT06448013GEMTUZUMAB OZOGAMICINPHASE1ClinicalTrials.gov
NCT05994690GEMTUZUMAB OZOGAMICINPHASE3ClinicalTrials.gov
NCT05984199GEMTUZUMAB OZOGAMICINPHASE1/PHASE2ClinicalTrials.gov
NCT05955261GEMTUZUMAB OZOGAMICINPHASE2ClinicalTrials.gov
NCT05716009GEMTUZUMAB OZOGAMICINPHASE1ClinicalTrials.gov
NCT05662904GEMTUZUMAB OZOGAMICINPHASE1ClinicalTrials.gov

NIH grants 7225

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant1612,025NIH's project files
P30CA008748Cancer Center Support Grant1382,025NIH's project files
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)762,025NIH's project files
P30CA015704Cancer Center Support Grant692,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)652,025NIH's project files
P30CA016058Cancer Center Support Grant472,025NIH's project files
U19AI057229Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitro452,025NIH's project files
P01CA065493Off-the-Shelf Immune Effector Cells for Hematological Malignancies432,025NIH's project files
P01CA018029Adult Leukemia Research Center412,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant412,025NIH's project files

Papers 16122

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42809184PubTator, text miningPubMed
42795003PubTator, text miningPubMed
42787817PubTator, text miningPubMed
42779343PubTator, text miningPubMed
42763069PubTator, text miningPubMed
42755912PubTator, text miningPubMed
42744164PubTator, text miningPubMed
42742907PubTator, text miningPubMed
42712597PubTator, text miningPubMed
42707684PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license