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ROCK2: Rho associated coiled-coil containing protein kinase 2
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Gene · 9475

Papers3,801

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

21 to 40 of 3,801

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TitleJournalYearPMIDFound bySource
Wide-Range Quantification of Belumosudil in Patients with Chronic Graft-Versus-Host Disease by High-Performance Liquid Chromatography.Ther Drug Monit202642390828PubTator, text miningPubMed
Targeting of RhoA-ROCK pathway activators and linked molecular signaling in Alzheimer's disease: The paving dawn for future therapy.Neuroscience202642342024PubTator, text miningPubMed
Clinical significance of lncRNA EGFR-AS1 in gestational diabetes mellitus and its regulation of endothelial cell function.Ir J Med Sci202642340571PubTator, text miningPubMed
Immunomodulatory cytoskeleton of bionic periosteum affects mitochondrial dynamics to promote osteogenesis.Bioact Mater202642338506PubTator, text miningPubMed
Therapeutic Potential of miR-196a in Protecting Corneal Endothelial Cells From Senescence Through Mitochondrial and TGF-β Signaling Modulation.Transl Vis Sci Technol202642312904PubTator, text miningPubMed
Non-coding Regulatory Variants in ASD (Autism Spectrum Disorders) Disrupt CTCF Domains and Shape Cell-Type-Specific Neurodevelopmental Landscapes Revealed by Single-Cell Analyses and Cortical Organoids.
Res Sq202642281968PubTator, text miningPubMed
Chronic graft-versus-host disease.Nat Rev Dis Primers202642277051PubTator, text miningPubMed
Belumosudil in the Management of Heavily Pretreated Prolonged Chronic GVHD: A Retrospective Multicenter Real-World Study.Hematol Oncol202642198791PubTator, text miningPubMed
Immune-Checkpoint-Inhibitor-Related Cardiovascular Toxicities in Cancer: A Mechanistic Review of Molecular Pathways with AI-Assisted Literature Clustering.Int J Mol Sci202642196366PubTator, text miningPubMed
Rare variants in TTC7A, ROCK2 and LIMK2 suggest a role for the ROCK-signaling pathway in isolated intestinal malrotation.Pediatr Surg Int202642185554PubTator, text miningPubMed
Rational Optimization of Rho-Associated Coiled-Coil Containing Protein Kinase 2 Inhibitors via Disruption of Molecular Planarity for Pulmonary Fibrosis.J Med Chem202642183679PubTator, text miningPubMed
Role of ROCK-associated inflammation and redox imbalance in Parkinson's disease dyskinesia: evidence from animal and patient studies.Int Immunopharmacol202642161054PubTator, text miningPubMed
The antiplatelet activity of 6-piperazinyl-purine analogues bearing nitrate esters is determined by the length of the carbon side chain.Eur J Pharmacol202642142574PubTator, text miningPubMed
Downregulating ROCK2 by human umbilical cord mesenchymal stem cells promotes pro-resolving microglial polarization and alleviates cerebral injury in germinal matrix hemorrhage.Cell Transplant202642141983PubTator, text miningPubMed
RPE With ROCK-Mediated Epithelial-Mesenchymal Transition as a Key Contributor of Subretinal Fibrosis in AMD.Invest Ophthalmol Vis Sci202642132459PubTator, text miningPubMed
ROCK2 inhibitor targets vascular niche angiocrine signaling in liver fibrosis.Trends Pharmacol Sci202642128717PubTator, text miningPubMed
Identification, toxicity evaluation, and HPLC-based quality control method development of process-related impurities and degradation products of belumosudil mesylate.J Pharm Biomed Anal202642127555PubTator, text miningPubMed
[Characterization of copy number variations in concomitant exotropia using single nucleotide polymorphism microarray].Zhonghua Yan Ke Za Zhi202642103667PubTator, text miningPubMed
Sinomenine attenuates the growth and immune evasion of gastric cancer by regulating the METTL3/MEST-mediated RhoA/ROCK2 signaling pathway.Pathol Res Pract202642102486PubTator, text miningPubMed
Aurora A kinase activation contributes to the fibrotic phenotype in systemic sclerosis through primary cilia shortening.Arthritis Res Ther202642098768PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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