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Gene · 9495

AKAP5: A-kinase anchoring protein 5

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. AKAP5: A-kinase anchoring protein 5. Genes, record 9495. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9495

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Gene

Symbol
AKAP5
HGNC
Name
A-kinase anchoring protein 5
HGNC
NCBI Gene ID
9495
NCBI Gene
HGNC ID
HGNC:375
HGNC
Ensembl
ENSG00000179841
NCBI Gene
Aliases
AKAP75, AKAP79, H21
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P24588A-kinase anchor protein 54273Ensembl, GeneID, HGNC

Source UniProt

Patents14

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-294605P24588Espacenet
JP 2025517969 A2025-06-124605P24588Espacenet
JP 2025062604 A2025-04-14651P24588Espacenet
JP 2025062604 A2025-04-14652P24588Espacenet
US 11446398 B22022-09-20651P24588Espacenet
US 11446398 B22022-09-20652P24588Espacenet
JP 2022524081 A2022-04-27103622P24588Espacenet
JP 2022524081 A2022-04-27103623P24588Espacenet
EP 3890777 A12021-10-132P24588Espacenet
US 11078247 B22021-08-03400P24588Espacenet

1 to 10 of 14

See all 14 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants771

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleAKAP5 papersNewest fiscal year
R01DK073368Mechanisms of Compartmentalized cAMP Signaling92025
R35CA197622Live-cell Activity Architecture in Cancer72025
R01AG055357Dysregulation of Cav1.2 by beta amyloid peptide62025
T32HL007828Cardiovascular Research Training Program62025
R01AI040127Signal transduction and gene induction in lymphocytes42025
R01DK119192Defective PKA Signaling in Cushing's Syndrome32025
R35GM136243Elucidating calcineurin signaling mechanisms at membranes32025
T32HL007446Pathobiology of Occlusive Vascular Disease32025
T32HL086350Training Program in Basic and Translational Cardiovascular Science32025
R01DK057236Electrophysiological Events Underlying Human Gastric Motility.22025

1 to 10 of 771Source NIH's project files

See all 771 nih grants

Papers1,362

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Nanoscale Architecture Can Control Cellular Function.ACS Nano202642689713PubTator, text miningPubMed
The scaffolding protein AKAP79/150 shapes innate immune responses to allergen.J Immunol202642406837PubTator, text miningPubMed
New Cyclopeptides and Curvularins from Marine-Derived Fungal-Bacterial Symbiont Aspergillus spelaeus GXIMD 04541/Sphingomonas echinoides GXIMD 04532.Mar Drugs202641892970PubTator, text miningPubMed
Smiling and first impressions in ad hoc entrustment decisions: An avatar-based simulation study.GMS J Med Educ202641767721PubTator, text miningPubMed
A monoclonal antibody targeting the C-terminal of α-synuclein fibrils mitigates pathology in a Parkinson's disease model.Cell Rep202641575853PubTator, text miningPubMed
Modeling teacher education students' adoption of large language models through an extended technology acceptance framework.Sci Rep202540890159PubTator, text miningPubMed
Synthetic Multiepitope Protein-Based Plasmonic Immunosensor for Rapid, Label-Free Detection of Cryptococcus Antibodies in Human Serum.ACS Infect Dis202540752014PubTator, text miningPubMed
Dysregulated calcium signaling in the aged primate association cortices: vulnerability to Alzheimer's disease neuropathology.Front Aging Neurosci202540735190PubTator, text miningPubMed
The evolution of AKAPs and emergence of PKA isotype selective anchoring determinants.J Biol Chem202540199400PubTator, text miningPubMed
Withdrawal: RNA Silencing Identifies PDE4D5 as the Functionally Relevant cAMP Phosphodiesterase Interacting with βArrestin to Control the Protein Kinase A/AKAP79-mediated Switching of the β2-Adrenergic Receptor to Activation of ERK in HEK293B2 Cells.
J Biol Chem202539961194PubTator, text miningPubMed

1 to 10 of 1,362

See all 1,362 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9495

GET https://conductscience.org/api/genes/v1/9495/patents