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Gene · 9510

ADAMTS1: ADAM metallopeptidase with thrombospondin type 1 motif 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ADAMTS1: ADAM metallopeptidase with thrombospondin type 1 motif 1. Genes, record 9510. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9510

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Gene

Symbol
ADAMTS1
HGNC
Name
ADAM metallopeptidase with thrombospondin type 1 motif 1
HGNC
NCBI Gene ID
9510
NCBI Gene
HGNC ID
HGNC:217
HGNC
Ensembl
ENSG00000154734
NCBI Gene
Aliases
C3-C5, KIAA1346, METH1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UHI8A disintegrin and metalloproteinase with thrombospondin motifs 19674Ensembl, GeneID, HGNC

Source UniProt

Patents104

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1436442Q9UHI8Espacenet
EP 4650780 A22025-11-193242Q9UHI8Espacenet
KR 1020250155128 A2025-10-301Q9UHI8Espacenet
KR 1020250155129 A2025-10-301Q9UHI8Espacenet
EP 4641201 A22025-10-292817Q9UHI8Espacenet
JP 2025147176 A2025-10-06316Q9UHI8Espacenet
JP 2025529142 A2025-09-04281Q9UHI8Espacenet
JP 2025529142 A2025-09-045382Q9UHI8Espacenet
US 12371689 B22025-07-29281Q9UHI8Espacenet
US 12371689 B22025-07-295382Q9UHI8Espacenet

1 to 10 of 104

See all 104 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,553

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleADAMTS1 papersNewest fiscal year
P30CA006973Regional Oncology Research Center72025
P30AG028716Duke Claude D. Pepper Older Americans Independence Center42025
P30CA016672Cancer Center Support Grant42025
P30CA068485Cancer Center Support Grant42025
R01HL098967The role of hypoxia in venous neointimal hyperplasia in hemodialysis grafts42025
P30CA008748Cancer Center Support Grant32025
P30CA014520UW Comprehensive Cancer Center Support32025
P30EY010572Ophthalmology Core Facility32025
P50CA097186The Pacific Northwest Prostate Cancer SPORE32025
R01DK063114Long-term effects of acute renal failure32025

1 to 10 of 1,553Source NIH's project files

See all 1,553 nih grants

Papers2,092

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Phosgene inhalation injury in mice: Modeling human pathophysiology, biomarker discovery, and therapeutic target identification.Toxicol Appl Pharmacol202642575345PubTator, text miningPubMed
Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production.Biotechnol Bioeng202642478279PubTator, text miningPubMed
Enhanced expression of ADAMTS1 in ovarian carcinomas: loss of ADAMTS1 expression instigates cellular reprogramming of extracellular matrix ensuing altered plasticity, augmented migration and attenuated adhesion.
J Biomed Sci202642332735PubTator, text miningPubMed
Targeting the DNA methylation-H3K27me3 switch reverses castration resistance and immunosuppression via ADAMTS1-driven collagenolysis.Proc Natl Acad Sci U S A202642313934PubTator, text miningPubMed
Unraveling Let-7f in oncology: a tumor suppressor with emerging clinical significance.Front Cell Dev Biol202642293764PubTator, text miningPubMed
Alterations in gene expression and protein levels of extracellular matrix-related molecules in major depressive disorder: Insights from analyses in the hippocampus and prefrontal cortex.Neurobiol Dis202642229016PubTator, text miningPubMed
Bioinformatics and experimental validation of druggable targets in non-alcoholic fatty liver disease.Sci Rep202642162172PubTator, text miningPubMed
Interleukin-4 alleviate polycystic ovary syndrome through promoting the polarization of M2 type macrophages via targeting NF-κB/IκB pathway.Eur J Pharmacol202642119768PubTator, text miningPubMed
Deciphering the regulatory mechanism and therapeutic potential of ECM degradation in intervertebral disc degeneration via multi-omics integration.Front Immunol202642099639PubTator, text miningPubMed
Exploring Ebola virus-associated gene expression through comparative analysis.Front Genet202642080095PubTator, text miningPubMed

1 to 10 of 2,092

See all 2,092 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9510

GET https://conductscience.org/api/genes/v1/9510/patents?page=2