Gene · 9510
ADAMTS1: ADAM metallopeptidase with thrombospondin type 1 motif 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ADAMTS1: ADAM metallopeptidase with thrombospondin type 1 motif 1. Genes, record 9510. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9510
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9UHI8 | A disintegrin and metalloproteinase with thrombospondin motifs 1 | 967 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents104
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 36442 | Q9UHI8 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3242 | Q9UHI8 | Espacenet |
| KR 1020250155128 A | 2025-10-30 | 1 | Q9UHI8 | Espacenet |
| KR 1020250155129 A | 2025-10-30 | 1 | Q9UHI8 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 2817 | Q9UHI8 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 316 | Q9UHI8 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 281 | Q9UHI8 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 5382 | Q9UHI8 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 281 | Q9UHI8 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 5382 | Q9UHI8 | Espacenet |
1 to 10 of 104
See all 104 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,553
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ADAMTS1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA006973 | Regional Oncology Research Center | 7 | 2025 |
| P30AG028716 | Duke Claude D. Pepper Older Americans Independence Center | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 4 | 2025 |
| R01HL098967 | The role of hypoxia in venous neointimal hyperplasia in hemodialysis grafts | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA014520 | UW Comprehensive Cancer Center Support | 3 | 2025 |
| P30EY010572 | Ophthalmology Core Facility | 3 | 2025 |
| P50CA097186 | The Pacific Northwest Prostate Cancer SPORE | 3 | 2025 |
| R01DK063114 | Long-term effects of acute renal failure | 3 | 2025 |
1 to 10 of 1,553Source NIH's project files
See all 1,553 nih grantsPapers2,092
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Phosgene inhalation injury in mice: Modeling human pathophysiology, biomarker discovery, and therapeutic target identification. | Toxicol Appl Pharmacol | 2026 | 42575345 | PubTator, text mining | PubMed |
| Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production. | Biotechnol Bioeng | 2026 | 42478279 | PubTator, text mining | PubMed |
Enhanced expression of ADAMTS1 in ovarian carcinomas: loss of ADAMTS1 expression instigates cellular reprogramming of extracellular matrix ensuing altered plasticity, augmented migration and attenuated adhesion. | J Biomed Sci | 2026 | 42332735 | PubTator, text mining | PubMed |
| Targeting the DNA methylation-H3K27me3 switch reverses castration resistance and immunosuppression via ADAMTS1-driven collagenolysis. | Proc Natl Acad Sci U S A | 2026 | 42313934 | PubTator, text mining | PubMed |
| Unraveling Let-7f in oncology: a tumor suppressor with emerging clinical significance. | Front Cell Dev Biol | 2026 | 42293764 | PubTator, text mining | PubMed |
| Alterations in gene expression and protein levels of extracellular matrix-related molecules in major depressive disorder: Insights from analyses in the hippocampus and prefrontal cortex. | Neurobiol Dis | 2026 | 42229016 | PubTator, text mining | PubMed |
| Bioinformatics and experimental validation of druggable targets in non-alcoholic fatty liver disease. | Sci Rep | 2026 | 42162172 | PubTator, text mining | PubMed |
| Interleukin-4 alleviate polycystic ovary syndrome through promoting the polarization of M2 type macrophages via targeting NF-κB/IκB pathway. | Eur J Pharmacol | 2026 | 42119768 | PubTator, text mining | PubMed |
| Deciphering the regulatory mechanism and therapeutic potential of ECM degradation in intervertebral disc degeneration via multi-omics integration. | Front Immunol | 2026 | 42099639 | PubTator, text mining | PubMed |
| Exploring Ebola virus-associated gene expression through comparative analysis. | Front Genet | 2026 | 42080095 | PubTator, text mining | PubMed |
1 to 10 of 2,092
See all 2,092 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/9510
GET https://conductscience.org/api/genes/v1/9510/patents?page=2