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NPEPPS: aminopeptidase puromycin sensitive

1 protein, 41 patents, 1 drug, 9 trials, 4,069 NIH grants and 21,980 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolNPEPPSHGNC
Nameaminopeptidase puromycin sensitiveHGNC
NCBI Gene ID9520NCBI Gene
HGNC IDHGNC:7900HGNC
EnsemblENSG00000141279NCBI Gene
AliasesAAP-S, MP100, PSANCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P55786Puromycin-sensitive aminopeptidase9193Ensembl, GeneID, HGNCUniProt

Patents 41

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
US 12618845 B22026-05-0556P55786Espacenet
JP 2026065001 A2026-04-14209P55786Espacenet
JP 2026004568 A2026-01-1437248P55786Espacenet
KR 1020250169633 A2025-12-0319P55786Espacenet
EP 4650780 A22025-11-195305P55786Espacenet
EP 4641201 A22025-10-294894P55786Espacenet
EP 4605011 A22025-08-2719P55786Espacenet
EP 4605526 A12025-08-2719P55786Espacenet
JP 2025517969 A2025-06-124894P55786Espacenet
JP 2025517970 A2025-06-125305P55786Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
TOSEDOSTATCHEMBL2103847Aminopeptidase inhibitorINHIBITORChEMBL

Trials 9

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT02452346TOSEDOSTATPHASE22018-06-12ClinicalTrials.gov
NCT02352831TOSEDOSTATPHASE1/PHASE22018-12-17ClinicalTrials.gov
NCT01636609TOSEDOSTATPHASE1ClinicalTrials.gov
NCT01567059TOSEDOSTATPHASE2ClinicalTrials.gov
NCT01180426TOSEDOSTATPHASE2ClinicalTrials.gov
NCT00780598TOSEDOSTATPHASE2ClinicalTrials.gov
NCT00737555TOSEDOSTATPHASE1ClinicalTrials.gov
NCT00689000TOSEDOSTATPHASE1/PHASE2ClinicalTrials.gov
NCT00522938TOSEDOSTATPHASE1/PHASE2ClinicalTrials.gov

NIH grants 4069

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant2012,025NIH's project files
P30CA006973Regional Oncology Research Center1322,025NIH's project files
P50CA092629SPORE in Prostate Cancer722,025NIH's project files
P50CA097186The Pacific Northwest Prostate Cancer SPORE702,025NIH's project files
P30CA016672Cancer Center Support Grant532,025NIH's project files
ZIABC010655Prostate Cancer Imaging502,025NIH's project files
ZIACL040015Interventional Oncology462,025NIH's project files
ZIABC011081Prostate Section442,025NIH's project files
ZIDBC011242Center for Interventional Oncology372,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase342,025NIH's project files

Papers 21980

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827186PubTator, text miningPubMed
42824310PubTator, text miningPubMed
42819047PubTator, text miningPubMed
42817762PubTator, text miningPubMed
42816206PubTator, text miningPubMed
42813855PubTator, text miningPubMed
42812884PubTator, text miningPubMed
42808614PubTator, text miningPubMed
42807789PubTator, text miningPubMed
42803939PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license