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ENTPD1: ectonucleoside triphosphate diphosphohydrolase 1

1 protein, 162 patents, 0 drugs, 0 trials, 3,712 NIH grants and 7,736 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolENTPD1HGNC
Nameectonucleoside triphosphate diphosphohydrolase 1HGNC
NCBI Gene ID953NCBI Gene
HGNC IDHGNC:3363HGNC
EnsemblENSG00000138185NCBI Gene
AliasesATP-DPH, ATPDase, CD39, NTPDase-1, SPG64NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P49961Ectonucleoside triphosphate diphosphohydrolase 15100Ensembl, GeneID, HGNCUniProt

Patents 162

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026171886 A12026-08-202P49961Espacenet
JP 2026109617 A2026-07-011P49961Espacenet
JP 2026004568 A2026-01-1444694P49961Espacenet
EP 4667936 A22025-12-242P49961Espacenet
JP 2025539459 A2025-12-051P49961Espacenet
JP 2025172069 A2025-11-20682P49961Espacenet
WO 2025233266 A12025-11-131P49961Espacenet
JP 2025148452 A2025-10-077P49961Espacenet
JP 2025529142 A2025-09-041399P49961Espacenet
JP 2025116106 A2025-08-07249P49961Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3712

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant402,025NIH's project files
P30CA047904Cancer Center Support Grant342,025NIH's project files
P01AI045897A Tolerance Approach to Xenotransplantation332,025NIH's project files
U19AI082630Durable Alteration of the Human Immune system after Infection or Immunotherapy252,025NIH's project files
P30CA016672Cancer Center Support Grant242,025NIH's project files
R01HL117913The NOTCH Signaling Pathway in Large Vessel Vasculitis222,025NIH's project files
U19AI057266Vaccine and Infection Induced Immunity in the Young and Aged202,025NIH's project files
P01AI108545Synergies among inhibitory receptors in tolerance and disease142,025NIH's project files
P50CA097190Head and Neck Cancer SPORE142,025NIH's project files
R01HL142068T Cell Immunity in Giant Cell Arteritis142,025NIH's project files

Papers 7736

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42815694PubTator, text miningPubMed
42808109PubTator, text miningPubMed
42806482PubTator, text miningPubMed
42804348PubTator, text miningPubMed
42798844PubTator, text miningPubMed
42790893PubTator, text miningPubMed
42786841PubTator, text miningPubMed
42777607PubTator, text miningPubMed
42775202PubTator, text miningPubMed
42766426PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license