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Gene · 9531

BAG3: BAG cochaperone 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. BAG3: BAG cochaperone 3. Genes, record 9531. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9531

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Gene

Symbol
BAG3
HGNC
Name
BAG cochaperone 3
HGNC
NCBI Gene ID
9531
NCBI Gene
HGNC ID
HGNC:939
HGNC
Ensembl
ENSG00000151929
NCBI Gene
Aliases
BAG-3, BIS, CAIR-1, CMD1HH, CMT2JJ, HMND15, MFM6
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O95817BAG family molecular chaperone regulator 35750Ensembl, GeneID, HGNC

Source UniProt

Patents90

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4824266 A12026-10-2147O95817Espacenet
EP 4773979 A12026-07-15167O95817Espacenet
US 12564647 B22026-03-03204O95817Espacenet
KR 1020250169529 A2025-12-0310O95817Espacenet
EP 4650780 A22025-11-198565O95817Espacenet
WO 2025235491 A12025-11-13100O95817Espacenet
EP 4640849 A22025-10-291294O95817Espacenet
EP 4641201 A22025-10-298725O95817Espacenet
JP 2025531194 A2025-09-191O95817Espacenet
JP 2025531194 A2025-09-193O95817Espacenet

1 to 10 of 90

See all 90 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,566

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleBAG3 papersNewest fiscal year
R01NS059690Molecular Chaperones and Small Molecules232025
P30MH092177Comprehensive NeuroHIV Center182025
R01HL136737Cardiac Sarcomere Protein Quality Control in Health and Disease72025
P30CA016672Cancer Center Support Grant52025
K24AR073317Clinical and Translational studies in muscle disease42025
P30CA008748Cancer Center Support Grant42025
P30DK063491Diabetes Research Center (DRC)42025
P30EY005722Center Core Grant for Vision Research42025
R01AG073121BAG3 regulates Rab35 and the ESCRT/endolysosome pathway42025
R01AR068797Chaperone Dysfunction in Myopathy: Connecting Yeast Genetics with Mouse Models42025

1 to 10 of 1,566Source NIH's project files

See all 1,566 nih grants

Papers2,636

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
BAG3 coordinates astrocytic proteostasis of Alzheimer's disease-linked proteins via proteasome, autophagy, and retromer interactions.Proc Natl Acad Sci U S A202642804638PubTator, text miningPubMed
Genetic architecture and molecular pathogenesis of Parkinson's disease: emerging mechanisms and therapeutic targets.Metab Brain Dis202642803978PubTator, text miningPubMed
Genetic vulnerability and dynamic mechanical stress synergistically drive sarcomere failure in human iPSC-derived cardiomyocytes.Mater Today Bio202642765073PubTator, text miningPubMed
Heat shock proteins as modulators of cardiovascular health and disease: From cellular stress to clinical targets.Protein Pept Lett202642753677PubTator, text miningPubMed
Bioinformatics Screening and Preliminary Experimental Verification of Integrated Stress Response-Associated MYC and BAG3 in Chronic Obstructive Pulmonary Disease.Int J Chron Obstruct Pulmon Dis202642701775PubTator, text miningPubMed
Hypertrophic cardiomyopathy: a genome-wide association meta-analysis and polygenic risk score.J Med Genet202642697718PubTator, text miningPubMed
Chaperone-assisted selective autophagy (CASA) in polyglutamine-related diseases: From mechanisms to therapeutic perspectives.J Huntingtons Dis202642690709PubTator, text miningPubMed
Prevalence of Pathogenic Genetic Variants Across Heart Failure Etiologies in an Admixed Population.JACC Adv202642658137PubTator, text miningPubMed
Genetic Variants in HSP70 Family and BAG Co-Chaperone Genes: Associations with Coronary Artery Disease Risk and Potential Regulatory Effects.Int J Mol Sci202642653304PubTator, text miningPubMed
Mitophagy Facilitates Cytosolic Proteostasis to Preserve Cardiac Function.Circ Res202642644246PubTator, text miningPubMed

1 to 10 of 2,636

See all 2,636 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9531

GET https://conductscience.org/api/genes/v1/9531/patents?page=2