Gene · 9531
BAG3: BAG cochaperone 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. BAG3: BAG cochaperone 3. Genes, record 9531. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9531
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O95817 | BAG family molecular chaperone regulator 3 | 575 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents90
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4824266 A1 | 2026-10-21 | 47 | O95817 | Espacenet |
| EP 4773979 A1 | 2026-07-15 | 167 | O95817 | Espacenet |
| US 12564647 B2 | 2026-03-03 | 204 | O95817 | Espacenet |
| KR 1020250169529 A | 2025-12-03 | 10 | O95817 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 8565 | O95817 | Espacenet |
| WO 2025235491 A1 | 2025-11-13 | 100 | O95817 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 1294 | O95817 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 8725 | O95817 | Espacenet |
| JP 2025531194 A | 2025-09-19 | 1 | O95817 | Espacenet |
| JP 2025531194 A | 2025-09-19 | 3 | O95817 | Espacenet |
1 to 10 of 90
See all 90 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,566
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | BAG3 papers | Newest fiscal year |
|---|---|---|---|
| R01NS059690 | Molecular Chaperones and Small Molecules | 23 | 2025 |
| P30MH092177 | Comprehensive NeuroHIV Center | 18 | 2025 |
| R01HL136737 | Cardiac Sarcomere Protein Quality Control in Health and Disease | 7 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| K24AR073317 | Clinical and Translational studies in muscle disease | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 4 | 2025 |
| P30EY005722 | Center Core Grant for Vision Research | 4 | 2025 |
| R01AG073121 | BAG3 regulates Rab35 and the ESCRT/endolysosome pathway | 4 | 2025 |
| R01AR068797 | Chaperone Dysfunction in Myopathy: Connecting Yeast Genetics with Mouse Models | 4 | 2025 |
1 to 10 of 1,566Source NIH's project files
See all 1,566 nih grantsPapers2,636
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| BAG3 coordinates astrocytic proteostasis of Alzheimer's disease-linked proteins via proteasome, autophagy, and retromer interactions. | Proc Natl Acad Sci U S A | 2026 | 42804638 | PubTator, text mining | PubMed |
| Genetic architecture and molecular pathogenesis of Parkinson's disease: emerging mechanisms and therapeutic targets. | Metab Brain Dis | 2026 | 42803978 | PubTator, text mining | PubMed |
| Genetic vulnerability and dynamic mechanical stress synergistically drive sarcomere failure in human iPSC-derived cardiomyocytes. | Mater Today Bio | 2026 | 42765073 | PubTator, text mining | PubMed |
| Heat shock proteins as modulators of cardiovascular health and disease: From cellular stress to clinical targets. | Protein Pept Lett | 2026 | 42753677 | PubTator, text mining | PubMed |
| Bioinformatics Screening and Preliminary Experimental Verification of Integrated Stress Response-Associated MYC and BAG3 in Chronic Obstructive Pulmonary Disease. | Int J Chron Obstruct Pulmon Dis | 2026 | 42701775 | PubTator, text mining | PubMed |
| Hypertrophic cardiomyopathy: a genome-wide association meta-analysis and polygenic risk score. | J Med Genet | 2026 | 42697718 | PubTator, text mining | PubMed |
| Chaperone-assisted selective autophagy (CASA) in polyglutamine-related diseases: From mechanisms to therapeutic perspectives. | J Huntingtons Dis | 2026 | 42690709 | PubTator, text mining | PubMed |
| Prevalence of Pathogenic Genetic Variants Across Heart Failure Etiologies in an Admixed Population. | JACC Adv | 2026 | 42658137 | PubTator, text mining | PubMed |
| Genetic Variants in HSP70 Family and BAG Co-Chaperone Genes: Associations with Coronary Artery Disease Risk and Potential Regulatory Effects. | Int J Mol Sci | 2026 | 42653304 | PubTator, text mining | PubMed |
| Mitophagy Facilitates Cytosolic Proteostasis to Preserve Cardiac Function. | Circ Res | 2026 | 42644246 | PubTator, text mining | PubMed |
1 to 10 of 2,636
See all 2,636 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/9531
GET https://conductscience.org/api/genes/v1/9531/patents?page=2