Gene · 9563
H6PD: hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. H6PD: hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. Genes, record 9563. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9563
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O95479 | GDH/6PGL endoplasmic bifunctional protein | 791 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents28
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 49032 | O95479 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 9915 | O95479 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 6360 | O95479 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6567 | O95479 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6567 | O95479 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 9915 | O95479 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 6360 | O95479 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 6360 | O95479 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 6367 | O95479 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 38215 | O95479 | Espacenet |
1 to 10 of 28
See all 28 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants918
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | H6PD papers | Newest fiscal year |
|---|---|---|---|
| P30CA177558 | University of Kentucky Markey Cancer Center – Cancer Center Support Grant | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 3 | 2025 |
| P30CA023074 | University of Arizona Cancer Center - Cancer Center Support Grant | 3 | 2025 |
| P30CA086862 | Cancer Center Support Grant | 3 | 2025 |
| P30ES006694 | Southwest Environmental Health Sciences Center | 3 | 2025 |
| P20GM121327 | University of Kentucky Center for Cancer Metabolism | 2 | 2025 |
| P30AI027763 | UCSF-Bay Area Center for AIDS Research | 2 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 2 | 2025 |
| P30CA016520 | Abramson Cancer Center Support Grant | 2 | 2025 |
1 to 10 of 918Source NIH's project files
See all 918 nih grantsPapers3,177
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Efficient Myoinositol biosynthesis from glucose through gluconate bypass of glycolysis. | Bioresour Technol | 2026 | 42800485 | PubTator, text mining | PubMed |
| Comparative study of the effects of different carbon substrates on acidification-driven mineral weathering by Pseudomonas. | Appl Environ Microbiol | 2026 | 42770714 | PubTator, text mining | PubMed |
| A Reduced-Acidification Phenotype Simplifies Strain Engineering in Komagataeibacter and Enables One-Step Production of Melanated Bacterial Cellulose. | Polymers (Basel) | 2026 | 42737108 | PubTator, text mining | PubMed |
| Glucose Oxidoreductases for Glucose Monitoring: A Bird's Eye View of Glucose-Sensing Enzymes II. | J Diabetes Sci Technol | 2026 | 42648724 | PubTator, text mining | PubMed |
| Hydrophilic PVI-HEA-Based Osmium Redox Polymers for Enhanced Electrochemical Glucose Sensing. | Biosensors (Basel) | 2026 | 42645048 | PubTator, text mining | PubMed |
| Structure-guided multi-domain engineering of glucose dehydrogenase for enhanced catalytic efficiency and cofactor regeneration. | Enzyme Microb Technol | 2026 | 42623864 | PubTator, text mining | PubMed |
| Host DNA repair factors empower a mechanism of antiviral nucleoside analog resistance. | Proc Natl Acad Sci U S A | 2026 | 42607204 | PubTator, text mining | PubMed |
| Mechanical unloading promotes adult cardiomyocyte proliferation through epicardial NRG1-ERBB4 signaling. | Nat Cardiovasc Res | 2026 | 42557396 | PubTator, text mining | PubMed |
| Identification of circulating biomarkers and immune subtypes for diabetic retinopathy through multi-cohort integrative analysis. | Diab Vasc Dis Res | 2026 | 42549570 | PubTator, text mining | PubMed |
| Reprogramming ligand-receptor interactions via a self-powered molecular engine for proton-responsive regulation of cellular motility. | Biosens Bioelectron | 2026 | 42546385 | PubTator, text mining | PubMed |
1 to 10 of 3,177
See all 3,177 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/9563
GET https://conductscience.org/api/genes/v1/9563/patents?page=2