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Gene · 9563

H6PD: hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. H6PD: hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. Genes, record 9563. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9563

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Gene

Symbol
H6PD
HGNC
Name
hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase
HGNC
NCBI Gene ID
9563
NCBI Gene
HGNC ID
HGNC:4795
HGNC
Ensembl
ENSG00000049239
NCBI Gene
Aliases
CORTRD1, G6PDH, GDH, H6PDH
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O95479GDH/6PGL endoplasmic bifunctional protein7911Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1449032O95479Espacenet
EP 4650780 A22025-11-199915O95479Espacenet
JP 2025147176 A2025-10-066360O95479Espacenet
JP 2025529142 A2025-09-046567O95479Espacenet
US 12371689 B22025-07-296567O95479Espacenet
JP 2025517970 A2025-06-129915O95479Espacenet
JP 2025028160 A2025-02-286360O95479Espacenet
KR 1020250010750 A2025-01-216360O95479Espacenet
JP 2024109657 A2024-08-146367O95479Espacenet
US 11446398 B22022-09-2038215O95479Espacenet

1 to 10 of 28

See all 28 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants918

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleH6PD papersNewest fiscal year
P30CA177558University of Kentucky Markey Cancer Center – Cancer Center Support Grant62025
P30CA016672Cancer Center Support Grant42025
P30CA016086Cancer Center Support Grant32025
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant32025
P30CA086862Cancer Center Support Grant32025
P30ES006694Southwest Environmental Health Sciences Center32025
P20GM121327University of Kentucky Center for Cancer Metabolism22025
P30AI027763UCSF-Bay Area Center for AIDS Research22025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant22025
P30CA016520Abramson Cancer Center Support Grant22025

1 to 10 of 918Source NIH's project files

See all 918 nih grants

Papers3,177

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Efficient Myoinositol biosynthesis from glucose through gluconate bypass of glycolysis.Bioresour Technol202642800485PubTator, text miningPubMed
Comparative study of the effects of different carbon substrates on acidification-driven mineral weathering by Pseudomonas.Appl Environ Microbiol202642770714PubTator, text miningPubMed
A Reduced-Acidification Phenotype Simplifies Strain Engineering in Komagataeibacter and Enables One-Step Production of Melanated Bacterial Cellulose.Polymers (Basel)202642737108PubTator, text miningPubMed
Glucose Oxidoreductases for Glucose Monitoring: A Bird's Eye View of Glucose-Sensing Enzymes II.J Diabetes Sci Technol202642648724PubTator, text miningPubMed
Hydrophilic PVI-HEA-Based Osmium Redox Polymers for Enhanced Electrochemical Glucose Sensing.Biosensors (Basel)202642645048PubTator, text miningPubMed
Structure-guided multi-domain engineering of glucose dehydrogenase for enhanced catalytic efficiency and cofactor regeneration.Enzyme Microb Technol202642623864PubTator, text miningPubMed
Host DNA repair factors empower a mechanism of antiviral nucleoside analog resistance.Proc Natl Acad Sci U S A202642607204PubTator, text miningPubMed
Mechanical unloading promotes adult cardiomyocyte proliferation through epicardial NRG1-ERBB4 signaling.Nat Cardiovasc Res202642557396PubTator, text miningPubMed
Identification of circulating biomarkers and immune subtypes for diabetic retinopathy through multi-cohort integrative analysis.Diab Vasc Dis Res202642549570PubTator, text miningPubMed
Reprogramming ligand-receptor interactions via a self-powered molecular engine for proton-responsive regulation of cellular motility.Biosens Bioelectron202642546385PubTator, text miningPubMed

1 to 10 of 3,177

See all 3,177 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9563

GET https://conductscience.org/api/genes/v1/9563/patents?page=2