Gene · 9572
NR1D1: nuclear receptor subfamily 1 group D member 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NR1D1: nuclear receptor subfamily 1 group D member 1. Genes, record 9572. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9572
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P20393 | Nuclear receptor subfamily 1 group D member 1 | 614 | 5 | Ensembl, GeneID, HGNC |
Source UniProt
Patents54
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 56141 | P20393 | Espacenet |
| US 12496298 B2 | 2025-12-16 | 4 | P20393 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1198 | P20393 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 851 | P20393 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15415 | P20393 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 851 | P20393 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1198 | P20393 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15415 | P20393 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15415 | P20393 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15254 | P20393 | Espacenet |
1 to 10 of 54
See all 54 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,343
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NR1D1 papers | Newest fiscal year |
|---|---|---|---|
| P30DK019525 | University of Pennsylvania Diabetes Research Center | 17 | 2025 |
| P30CA014195 | Cancer Center Support Grant (CCSG) | 8 | 2025 |
| P30DK072476 | Pennington/Louisiana NORC | 7 | 2025 |
| P30ES013508 | Center of Excellence in Environmental Toxicology | 7 | 2025 |
| R01CA051497 | Defining the Role of the Cancer Circadian Clock in Tumor Immunity and Tumorigenesis | 6 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 5 | 2025 |
| P30DK056338 | Texas Medical Center Digestive Diseases Center | 5 | 2025 |
| ZIABC011191 | Preclinical Mouse Models of Thyroid Cancer | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
1 to 10 of 1,343Source NIH's project files
See all 1,343 nih grantsPapers2,029
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Diurnal Insulin Clearance and Circadian Metabolic Gene Signatures in MASLD: Integrative Multi-Dataset Physiological and Transcriptomic Analysis. | Metabolites | 2026 | 42783754 | PubTator, text mining | PubMed |
| Leptin Associates with Circadian Light Hygiene and REV-ERBα in Arctic Residents. | Bull Exp Biol Med | 2026 | 42771238 | PubTator, text mining | PubMed |
| Targeting the NR1D1-IGF2BP2-V-ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis-Induced Immunosuppression. | Adv Sci (Weinh) | 2026 | 42636084 | PubTator, text mining | PubMed |
| Letter to "NR1D2 Knockdown Alleviates Myocardial Infarction Through Nrf2 Signaling Pathway Activation". | Cardiovasc Drugs Ther | 2026 | 42579208 | PubTator, text mining | PubMed |
| Dictamnine alleviates oxidative stress in rheumatoid arthritis via modulation of the NR1D1-Keap1/Nrf2/ARE axis. | Bioorg Chem | 2026 | 42520520 | PubTator, text mining | PubMed |
| Impact of Core Circadian Gene Variants on Glycemic Parameters and Insulin Resistance in Type 2 Diabetes: A Systematic Review. | Cureus | 2026 | 42504374 | PubTator, text mining | PubMed |
| Retraction notice to "SR9009 attenuates inflammation-related NPMSC pyroptosis and IVDD through NR1D1/NLRP3/IL-1β pathway" [iScience 27 (2024) 109733]. | iScience | 2026 | 42491751 | PubTator, text mining | PubMed |
| Stephanoside B modulates metabolic gene expression and lengthens the circadian bmal1 oscillation period in differentiated myotubes revealed by real-time bioluminescence. | Mol Biol Rep | 2026 | 42484698 | PubTator, text mining | PubMed |
| Immune-stromal dysregulation and senescence in chronic spontaneous urticaria. | J Allergy Clin Immunol Glob | 2026 | 42436760 | PubTator, text mining | PubMed |
| Neuroinflammatory suppression of astrocytic BMAL1 defines a selective reactive astrocyte program. | J Neuroinflammation | 2026 | 42421063 | PubTator, text mining | PubMed |
1 to 10 of 2,029
See all 2,029 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/9572
GET https://conductscience.org/api/genes/v1/9572/patents?page=2