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Gene · 9589

WTAP: WT1 associated protein

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. WTAP: WT1 associated protein. Genes, record 9589. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9589

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Gene

Symbol
WTAP
HGNC
Name
WT1 associated protein
HGNC
NCBI Gene ID
9589
NCBI Gene
HGNC ID
HGNC:16846
HGNC
Ensembl
ENSG00000146457
NCBI Gene
Aliases
KIAA0105, MGC3925, Mum2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15007Pre-mRNA-splicing regulator WTAP3966Ensembl, GeneID, HGNC

Source UniProt

Patents16

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1469872Q15007Espacenet
EP 4650780 A22025-11-197540Q15007Espacenet
JP 2025517970 A2025-06-127540Q15007Espacenet
JP 2024515999 A2024-04-1180Q15007Espacenet
US 11446398 B22022-09-2097687Q15007Espacenet
US 11446398 B22022-09-2097688Q15007Espacenet
JP 2022524081 A2022-04-27200658Q15007Espacenet
JP 2022524081 A2022-04-27200659Q15007Espacenet
US 11078247 B22021-08-0312646Q15007Espacenet
JP 2019054813 A2019-04-11250307Q15007Espacenet

1 to 10 of 16

See all 16 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants904

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleWTAP papersNewest fiscal year
RM1HG008935Center for dynamic RNA epitranscriptomes - Renewal192025
R01CA186702Mechanisms of epitranscriptomic regulation in cancer112025
P30CA054174Mays Cancer Center at UT Health SA102025
P30AI064518Center for AIDS Research62025
P30CA008748Cancer Center Support Grant62025
R01AI125416Defining the role of the RNA modification N6-methyladenosine during Flaviviridae virus infection62025
R01AI152543EPITRANSCRIPTOMIC REGULATION OF CYTOMEGALOVIRUS INFECTION62025
R01GM056927Control of Translation in Herpesvirus Infected Cells - Resubmission - 162025
R35NS111631New mechanisms and technologies for understanding post-transcriptional gene regulation in neurons62025
P30CA016672Cancer Center Support Grant52025

1 to 10 of 904Source NIH's project files

See all 904 nih grants

Papers3,474

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The m 6 A methyltransferase complex protein VIRMA engages hepatitis C virus RNA through a WTAP-independent mechanism.bioRxiv202642818783PubTator, text miningPubMed
BRD3OS Dysregulation in Antiphospholipid Syndrome: Integrative Network and RNA Structural Analysis of m6A-Related Candidate Regions.Biomolecules202642793095PubTator, text miningPubMed
Lactylation and N6-Methyladenosine RNA modification in neuropsychiatric sequelae after intracerebral hemorrhage: a hypothesis-generating metabolic-glial-circuit framework.Mol Biol Rep202642730969PubTator, text miningPubMed
CircRHBDD1(4,5) drives malignant progression of oral squamous cell carcinoma by enhancing DKK1 mRNA stability through facilitating m6A-dependent IGF2BP2 binding.Oncogene202642722719PubTator, text miningPubMed
RNA m⁶A modification and its regulatory factors are altered in granulosa cells from women with PMOS.J Assist Reprod Genet202642687053PubTator, text miningPubMed
WTAP-mediated m6A modification upregulates the circCDK8 to promote ferroptosis in periodontal ligament stem cells.Biochem Pharmacol202642679908PubTator, text miningPubMed
WTAP-mediated m6A RNA methylation promotes diabetic foot ulcer healing under negative pressure wound therapy.J Diabetes Investig202642669871PubTator, text miningPubMed
ACSL4-Dependent Lysosomal Lipid Peroxidation Links WTAP-Mediated m6A Modification to Intervertebral Disc Degeneration.Adv Sci (Weinh)202642666099PubTator, text miningPubMed
WTAP-Mediated m6A Modification of TXNDC5 mRNA Promotes Cervical Carcinogenesis.Kaohsiung J Med Sci202642598864PubTator, text miningPubMed
m6A-Mediated Stabilization of MRPS23 Drives NSCLC Progression Via HSPA8 and ERK Signaling Modulation.Cancer Sci202642593047PubTator, text miningPubMed

1 to 10 of 3,474

See all 3,474 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

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