Gene · 9619
ABCG1: ATP binding cassette subfamily G member 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ABCG1: ATP binding cassette subfamily G member 1. Genes, record 9619. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9619
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P45844 | ATP-binding cassette sub-family G member 1 | 678 | 5 | Ensembl, GeneID, HGNC |
Source UniProt
Patents39
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 38499 | P45844 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 21 | P45844 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 211 | P45844 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 5345 | P45844 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 211 | P45844 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 5345 | P45844 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 7834 | P45844 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 21 | P45844 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 21 | P45844 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 28 | P45844 | Espacenet |
1 to 10 of 39
See all 39 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,320
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ABCG1 papers | Newest fiscal year |
|---|---|---|---|
| P30DK017047 | Diabetes Research Center | 19 | 2025 |
| P01HL116263 | HDL Function in Human Disease | 18 | 2025 |
| R01HL107653 | Cholesterol efflux, CHIP and inflammasome activation | 16 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 14 | 2025 |
| ZIAES102005 | Cell Signaling of Host Defense | 13 | 2025 |
| ZIAHL006001 | Framingham Project/Levy | 10 | 2025 |
| ZIAHL006095 | Development of Apo Mimetic Peptides for the Treatment Cardiovascular Disease | 9 | 2025 |
| K24HL146838 | Mentoring Patient-Oriented Research in Deep Lipid Phenotyping for Cardiovascular Disease | 8 | 2025 |
| P01HL151328 | Triglycerides, Diabetes and Cardiovascular Disease | 8 | 2025 |
| P30DK020541 | NYR-Diabetes Research Center (NYR-DRC) | 8 | 2025 |
1 to 10 of 2,320Source NIH's project files
See all 2,320 nih grantsPapers3,998
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Lipid signaling and foam cell formation in atherosclerosis and spinal cord injury. | J Lipid Res | 2026 | 42767505 | PubTator, text mining | PubMed |
| Demethylase FTO attenuates atherosclerotic plaque via upregulating ABCA1 and ABCG1 expression by targeting ATG5. | Mol Med Rep | 2026 | 42757464 | PubTator, text mining | PubMed |
| Lipid metabolic reprogramming in clear cell renal cell carcinoma: focus on high-density lipoprotein-related pathways. | Oncol Rev | 2026 | 42745992 | PubTator, text mining | PubMed |
| Sustained estimated VLDL-C exposure is associated with cardiometabolic multimorbidity and foam cell dysfunction: evidence from prospective cohorts and in vitro studies. | J Geriatr Cardiol | 2026 | 42741040 | PubTator, text mining | PubMed |
| ABCA1 as a Gatekeeper of Pancreatic β-Cell Cholesterol Homeostasis: Links Between Lipoprotein Stress, Lipotoxicity, and Insulin Secretion. | Nutrients | 2026 | 42739051 | PubTator, text mining | PubMed |
| Vitamin D alleviates indoxyl sulfate-induced inflammatory and cholesterol dysregulation in macrophages: Implications for vascular health in patients receiving hemodialysis. | PLoS One | 2026 | 42726742 | PubTator, text mining | PubMed |
| High TG/low HDL-C ratio-mimetic lipid stress drives diabetic atherosclerotic endothelial-macrophage dysfunction through glycocalyx disruption and CD36/ABCA1 imbalance. | J Mol Histol | 2026 | 42717131 | PubTator, text mining | PubMed |
| The regulation of COX-2, ABCA1, and ABCG1 by the lncRNA PACERR links the inflammatory response and cholesterol homeostasis. | Cell Rep | 2026 | 42696452 | PubTator, text mining | PubMed |
| Decoding the crosstalk: interplay between macrophage programmed cell death networks and cholesterol efflux. | Front Cardiovasc Med | 2026 | 42677108 | PubTator, text mining | PubMed |
| NOTCH3 Mutations in CADASIL Alter Lipid Metabolism: Insights from Patient Plasma and In Vitro Models. | Neurochem Res | 2026 | 42627555 | PubTator, text mining | PubMed |
1 to 10 of 3,998
See all 3,998 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/9619
GET https://conductscience.org/api/genes/v1/9619/patents?page=2