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Gene · 9619

ABCG1: ATP binding cassette subfamily G member 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ABCG1: ATP binding cassette subfamily G member 1. Genes, record 9619. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9619

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Gene

Symbol
ABCG1
HGNC
Name
ATP binding cassette subfamily G member 1
HGNC
NCBI Gene ID
9619
NCBI Gene
HGNC ID
HGNC:73
HGNC
Ensembl
ENSG00000160179
NCBI Gene
Aliases
ABC8, WHITE1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P45844ATP-binding cassette sub-family G member 16785Ensembl, GeneID, HGNC

Source UniProt

Patents39

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1438499P45844Espacenet
JP 2025147176 A2025-10-0621P45844Espacenet
JP 2025529142 A2025-09-04211P45844Espacenet
JP 2025529142 A2025-09-045345P45844Espacenet
US 12371689 B22025-07-29211P45844Espacenet
US 12371689 B22025-07-295345P45844Espacenet
JP 2025062604 A2025-04-147834P45844Espacenet
JP 2025028160 A2025-02-2821P45844Espacenet
KR 1020250010750 A2025-01-2121P45844Espacenet
JP 2024109657 A2024-08-1428P45844Espacenet

1 to 10 of 39

See all 39 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,320

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleABCG1 papersNewest fiscal year
P30DK017047Diabetes Research Center192025
P01HL116263HDL Function in Human Disease182025
R01HL107653Cholesterol efflux, CHIP and inflammasome activation162025
P30DK063491Diabetes Research Center (DRC)142025
ZIAES102005Cell Signaling of Host Defense132025
ZIAHL006001Framingham Project/Levy102025
ZIAHL006095Development of Apo Mimetic Peptides for the Treatment Cardiovascular Disease92025
K24HL146838Mentoring Patient-Oriented Research in Deep Lipid Phenotyping for Cardiovascular Disease82025
P01HL151328Triglycerides, Diabetes and Cardiovascular Disease82025
P30DK020541NYR-Diabetes Research Center (NYR-DRC)82025

1 to 10 of 2,320Source NIH's project files

See all 2,320 nih grants

Papers3,998

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Lipid signaling and foam cell formation in atherosclerosis and spinal cord injury.J Lipid Res202642767505PubTator, text miningPubMed
Demethylase FTO attenuates atherosclerotic plaque via upregulating ABCA1 and ABCG1 expression by targeting ATG5.Mol Med Rep202642757464PubTator, text miningPubMed
Lipid metabolic reprogramming in clear cell renal cell carcinoma: focus on high-density lipoprotein-related pathways.Oncol Rev202642745992PubTator, text miningPubMed
Sustained estimated VLDL-C exposure is associated with cardiometabolic multimorbidity and foam cell dysfunction: evidence from prospective cohorts and in vitro studies.J Geriatr Cardiol202642741040PubTator, text miningPubMed
ABCA1 as a Gatekeeper of Pancreatic β-Cell Cholesterol Homeostasis: Links Between Lipoprotein Stress, Lipotoxicity, and Insulin Secretion.Nutrients202642739051PubTator, text miningPubMed
Vitamin D alleviates indoxyl sulfate-induced inflammatory and cholesterol dysregulation in macrophages: Implications for vascular health in patients receiving hemodialysis.PLoS One202642726742PubTator, text miningPubMed
High TG/low HDL-C ratio-mimetic lipid stress drives diabetic atherosclerotic endothelial-macrophage dysfunction through glycocalyx disruption and CD36/ABCA1 imbalance.J Mol Histol202642717131PubTator, text miningPubMed
The regulation of COX-2, ABCA1, and ABCG1 by the lncRNA PACERR links the inflammatory response and cholesterol homeostasis.Cell Rep202642696452PubTator, text miningPubMed
Decoding the crosstalk: interplay between macrophage programmed cell death networks and cholesterol efflux.Front Cardiovasc Med202642677108PubTator, text miningPubMed
NOTCH3 Mutations in CADASIL Alter Lipid Metabolism: Insights from Patient Plasma and In Vitro Models.Neurochem Res202642627555PubTator, text miningPubMed

1 to 10 of 3,998

See all 3,998 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9619

GET https://conductscience.org/api/genes/v1/9619/patents?page=2