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Gene · 963

CD53: CD53 molecule

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CD53: CD53 molecule. Genes, record 963. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/963

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Gene

Symbol
CD53
HGNC
Name
CD53 molecule
HGNC
NCBI Gene ID
963
NCBI Gene
HGNC ID
HGNC:1686
HGNC
Ensembl
ENSG00000143119
NCBI Gene
Aliases
MOX44, TSPAN25
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P19397Leukocyte surface antigen CD532191Ensembl, GeneID, HGNC

Source UniProt

Patents43

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1440581P19397Espacenet
JP 2025529142 A2025-09-04824P19397Espacenet
US 12371689 B22025-07-29824P19397Espacenet
US 12146238 B22024-11-1990P19397Espacenet
EP 4299137 A22024-01-032P19397Espacenet
JP 2022540768 A2022-09-205P19397Espacenet
JP 2022540768 A2022-09-2010P19397Espacenet
US 11446398 B22022-09-2013201P19397Espacenet
US 11400116 B22022-08-02161P19397Espacenet
US 11400116 B22022-08-02824P19397Espacenet

1 to 10 of 43

See all 43 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants906

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCD53 papersNewest fiscal year
P30CA008748Cancer Center Support Grant62025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant32025
P30DK052574Host-environment interactions in the pathophysiology of digestive disease32025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)22025
P30CA016672Cancer Center Support Grant22025
P30CA091842Cancer Center Support Grant22025
P30DK058404Molecular and Cellular Basis for Digestive Diseases22025
P30EY003790Core Grant for Vision Research22025
R01HL122483Functional Role of Tetraspanin CD82 in Hematopoietic Stem Cell Interactions22025
T32AI007290Molecular and Cellular Immunobiology22025

1 to 10 of 906Source NIH's project files

See all 906 nih grants

Papers1,502

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Identification of PD-1-Related Genes as Prognostic Biomarkers in Lung Adenocarcinoma.Hum Mutat202642643623PubTator, text miningPubMed
The translational potential of m6A RNA methylation in DKD: emerging biomarkers for early detection and targeted therapies.Front Med (Lausanne)202642559138PubTator, text miningPubMed
Single cell multi-omics enables high-resolution identification and functional purification of human acute myeloid leukemia stem cells.bioRxiv202642523402PubTator, text miningPubMed
Systems-level analyses and clinical validation highlight CD53 as a diagnostic and prognostic marker in lung adenocarcinoma.Front Cell Dev Biol202642368459PubTator, text miningPubMed
Extracellular vesicle cargo dynamics in the bone marrow microenvironment: from hematopoietic homeostasis to malignant transformation.Extracell Vesicle202642344609PubTator, text miningPubMed
Integrative transcriptomic and systems biology analysis of public SLE datasets identifies immune regulatory pathways.J Comput Aided Mol Des202642295464PubTator, text miningPubMed
Exploring key biomarkers associated with axillary lymph node metastasis in breast cancer using single-cell RNA sequencing and Mendelian randomization.Int J Biol Markers202642121358PubTator, text miningPubMed
Pathogenic implication of the CD53 tetraspanin in immune and cancer cells.Biochim Biophys Acta Mol Cell Res202641921791PubTator, text miningPubMed
Integrated bioinformatics and machine learning to explore the common mechanisms and potential biomarkers between periodontitis and preterm birth.Front Cell Dev Biol202641799432PubTator, text miningPubMed
Integrating computational engines to identify TSPAN6 as a migrasome-associated target for immunotherapy sensitization.Front Immunol202641782878PubTator, text miningPubMed

1 to 10 of 1,502

See all 1,502 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/963

GET https://conductscience.org/api/genes/v1/963/patents?page=2