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IKBKE: inhibitor of nuclear factor kappa B kinase subunit epsilon

1 protein, 43 patents, 0 drugs, 0 trials, 3,181 NIH grants and 4,822 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolIKBKEHGNC
Nameinhibitor of nuclear factor kappa B kinase subunit epsilonHGNC
NCBI Gene ID9641NCBI Gene
HGNC IDHGNC:14552HGNC
EnsemblENSG00000263528NCBI Gene
AliasesIKK-E, IKK-i, IKKE, IKKI, KIAA0151NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q14164Inhibitor of nuclear factor kappa-B kinase subunit epsilon7160Ensembl, GeneID, HGNCUniProt

Patents 43

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1449770Q14164Espacenet
EP 4650780 A22025-11-1917534Q14164Espacenet
EP 4641201 A22025-10-2921648Q14164Espacenet
JP 2025517969 A2025-06-1221648Q14164Espacenet
JP 2025517970 A2025-06-1217534Q14164Espacenet
US 11446398 B22022-09-2040237Q14164Espacenet
JP 2022524081 A2022-04-27143208Q14164Espacenet
US 10918740 B22021-02-168647Q14164Espacenet
US 10869935 B22020-12-228647Q14164Espacenet
WO 2020239947 A12020-12-0394Q14164Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3181

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant252,025NIH's project files
P30CA008748Cancer Center Support Grant112,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant112,025NIH's project files
U54MD007582FAMU Center for Health Disparities Research102,025NIH's project files
P30CA068485Cancer Center Support Grant82,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award82,025NIH's project files
P30DK063491Diabetes Research Center (DRC)72,025NIH's project files
P30CA013330Cancer Center Support Grant62,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)62,025NIH's project files
P30DK036836Diabetes Research Center62,025NIH's project files

Papers 4822

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42820930PubTator, text miningPubMed
42568372PubTator, text miningPubMed
42454699PubTator, text miningPubMed
42430421PubTator, text miningPubMed
42421333PubTator, text miningPubMed
42414293PubTator, text miningPubMed
42367247PubTator, text miningPubMed
42240328PubTator, text miningPubMed
42199106PubTator, text miningPubMed
42198706PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license