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Gene · 970

CD70: CD70 molecule

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. CD70: CD70 molecule. Genes, record 970. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/970

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
CD70
HGNC
Name
CD70 molecule
HGNC
NCBI Gene ID
970
NCBI Gene
HGNC ID
HGNC:11937
HGNC
Ensembl
ENSG00000125726
NCBI Gene
Aliases
CD27-L, CD27L, CD27LG, LPFS3, TNFSF7, TNLG8A
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P32970CD70 antigen1931Ensembl, GeneID, HGNC

Source UniProt

Patents411

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4801963 A12026-09-09143P32970Espacenet
EP 4796562 A12026-08-26104P32970Espacenet
JP 2026086743 A2026-05-26172P32970Espacenet
US 12636345 B22026-05-2632P32970Espacenet
JP 2026516158 A2026-05-193P32970Espacenet
JP 2026062687 A2026-04-10139P32970Espacenet
EP 4722370 A12026-04-0823P32970Espacenet
EP 4709396 A12026-03-183P32970Espacenet
EP 4705273 A22026-03-11330P32970Espacenet
JP 2026000897 A2026-01-06335P32970Espacenet

1 to 10 of 411

See all 411 patents

Drugs4

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
CUSATUZUMABCHEMBL4297891CD70 antigen inhibitorINHIBITORChEMBL
MDX-1411CHEMBL2109492CD70 antigen cross-linking agentCROSS-LINKING AGENTChEMBL
VORSETUZUMABCHEMBL2108673CD70 antigen binding agentBINDING AGENTChEMBL
VORSETUZUMAB MAFODOTINCHEMBL2108672CD70 antigen binding agentBINDING AGENTChEMBL

Trials12

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06384261CUSATUZUMABPHASE2ClinicalTrials.gov
NCT04264806CUSATUZUMABPHASE2ClinicalTrials.gov
NCT04241549CUSATUZUMABPHASE1ClinicalTrials.gov
NCT04150887CUSATUZUMABPHASE1ClinicalTrials.gov
NCT04023526CUSATUZUMABPHASE22024-07-30ClinicalTrials.gov
NCT03030612CUSATUZUMABPHASE1/PHASE2ClinicalTrials.gov
NCT02759250CUSATUZUMABPHASE1ClinicalTrials.gov
NCT01813539CUSATUZUMABPHASE1/PHASE2ClinicalTrials.gov
NCT01677390VORSETUZUMAB MAFODOTINPHASE1ClinicalTrials.gov
NCT01015911VORSETUZUMAB MAFODOTINPHASE1ClinicalTrials.gov

1 to 10 of 12

See all 12 trials

NIH grants2,135

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA016672Cancer Center Support Grant312025
P30CA008748Cancer Center Support Grant302025
P30ES017885Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD)162025
P50CA126752SPORE in Lymphoma142025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant102025
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success92025
P30CA016056Roswell Park Cancer Center Support Grant62025
P30CA016520Abramson Cancer Center Support Grant62025
P30CA044579University of Virginia Cancer Center Support Grant62025
R01AI049954Gene Transcription in SLE62025

1 to 10 of 2,135Source NIH's project files

See all 2,135 nih grants

Papers4,349

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818546PubTator, text miningPubMed
42817846PubTator, text miningPubMed
42817840PubTator, text miningPubMed
42812140PubTator, text miningPubMed
42809589PubTator, text miningPubMed
42800662PubTator, text miningPubMed
42780029PubTator, text miningPubMed
42778210PubTator, text miningPubMed
42738247PubTator, text miningPubMed
42718816PubTator, text miningPubMed

1 to 10 of 4,349

See all 4,349 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/970

GET https://conductscience.org/api/genes/v1/970/patents?page=2