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Gene · 9709

HERPUD1: homocysteine inducible ER protein with ubiquitin like domain 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. HERPUD1: homocysteine inducible ER protein with ubiquitin like domain 1. Genes, record 9709. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9709

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Gene

Symbol
HERPUD1
HGNC
Name
homocysteine inducible ER protein with ubiquitin like domain 1
HGNC
NCBI Gene ID
9709
NCBI Gene
HGNC ID
HGNC:13744
HGNC
Ensembl
ENSG00000051108
NCBI Gene
Aliases
HERP, HERPUD1-IT1, KIAA0025, Mif1, SUP
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15011Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein3911Ensembl, GeneID, HGNC

Source UniProt

Patents47

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1449371Q15011Espacenet
EP 4650780 A22025-11-1913577Q15011Espacenet
EP 4640849 A22025-10-292380Q15011Espacenet
EP 4641201 A22025-10-2915572Q15011Espacenet
JP 2025529142 A2025-09-041939Q15011Espacenet
US 12371689 B22025-07-291939Q15011Espacenet
JP 2025519096 A2025-06-242380Q15011Espacenet
JP 2025517969 A2025-06-1215572Q15011Espacenet
JP 2025517970 A2025-06-1213577Q15011Espacenet
JP 2025032204 A2025-03-1129527Q15011Espacenet

1 to 10 of 47

See all 47 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,129

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleHERPUD1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant62025
ZIADK033008Mechanism of protein quality control at the endoplasmic reticulum62025
P30CA021765Cancer Center Support Grant (CCSG)52025
P30CA016672Cancer Center Support Grant42025
ZICES102445Gene Expression and Microarrays42025
IK6BX004209BLRD Research Career Scientist Award Application32025
P30CA068485Cancer Center Support Grant32025
P50AA011999Southern California Research Center for ALPD and Cirrhosis32025
R35GM133552Coordination of chaperone interactions that dictate protein folding and trafficking32025
ZIAES101586Nuclear receptors: action, functions, and roles in disease32025

1 to 10 of 1,129Source NIH's project files

See all 1,129 nih grants

Papers1,432

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Tazarotene-Induced Gene 2 Promotes Melanoma Cell Death via the Activation of Endoplasmic Reticulum Stress.Front Biosci (Landmark Ed)202642689973PubTator, text miningPubMed
Ferroptosis-Based Peripheral Immune Dysregulation and Diagnostic Signatures in Parkinson's Disease: An RNA Transcriptomic and Single-Cell Immune Sequencing Analysis.FASEB J202642543885PubTator, text miningPubMed
CircRAD23B-208aa Promotes Gastric Cancer Progression by Activating the Unfolded Protein Response through PDIA5 SUMOylation.Research (Wash D C)202642491210PubTator, text miningPubMed
Dual-Acting Vitamin B3-Melanostatin Neuropeptide Hybrids as Potent Modulators of the Dopamine D2 Receptors with Neuroprotective Activity.J Med Chem202642312436PubTator, text miningPubMed
HERPUD1 suppresses porcine epidemic diarrhea virus replication by recruiting HRD1 to degrade viral ORF3 protein.J Virol202642307246PubTator, text miningPubMed
Discovery of bridged melanostatin derivatives as potent allosteric modulators of the dopamine D2 receptors with improved permeability.Biomed Pharmacother202642284887PubTator, text miningPubMed
Aminosteroid RM-581 Induces G0/G1 Arrest and Endoplasmic Reticulum Stress-Mediated Apoptosis in Human Acute and Chronic Leukemia Cell Lines.Cancers (Basel)202641976301PubTator, text miningPubMed
Regenerative Surgical Treatment of Peri-Implantitis: A Systematic Review and Meta-Analysis.Dent J (Basel)202641892788PubTator, text miningPubMed
Correction: HERP constrains white adipose expansion and inflammation by STEAP4 stabilization.Cell Death Differ202641876843PubTator, text miningPubMed
Microsporidian Encephalitozoon hellem inhibits host mitophagy by inducing ERAD to degrade BNIP3L.PLoS Pathog202641871091PubTator, text miningPubMed

1 to 10 of 1,432

See all 1,432 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9709

GET https://conductscience.org/api/genes/v1/9709/patents?page=2