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SETD1A: SET domain containing 1A, histone lysine methyltransferase
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Gene · 9739

Papers2,264

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

21 to 40 of 2,264

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TitleJournalYearPMIDFound bySource
Bivalency Erosion as a Unifying Mechanism of PFAS Inter- and Transgenerational Neurotoxicity.J Appl Toxicol202642165699PubTator, text miningPubMed
Case Report: Familial Cold Autoinflammatory Syndrome With Double Variant in NLRP12 and SETD1A.Case Rep Med202642157874PubTator, text miningPubMed
Decoding WDR5-Mediated Interactions in Gliomas: Implications for Targeted Therapy.Med Res Rev202642131930PubTator, text miningPubMed
The KMT2F histone methyltransferase interacts with the RNA polymerase I machinery to promote ribosomal RNA transcription.PLoS Biol202642096476PubTator, text miningPubMed
COMPASS-mediated epigenetic regulation of transcription accelerates forgetting with age.Res Sq202642094054PubTator, text miningPubMed
Comparison of Objective and Subjective Indicators in Patients with Idiopathic Scoliosis Undergoing PSSE Therapy-Retrospective Observational.Medicina (Kaunas)202642075524PubTator, text miningPubMed
Genome-wide CRISPR screen identifies TAF1C as an epigenetic determinant of lipid deposition via ACSL4-dependent ferroptosis in MASLD.J Adv Res202642031105PubTator, text miningPubMed
Epigenetic regulators polyphenols in neurodegenerative diseases: a promising intervention strategy.Ann Med202641918250PubTator, text miningPubMed
SETD1A Regulates Glycolysis and Senescence of Nucleus Pulposus Cells via H3K4me3-HELZ2/PPARα-HIF1α Axis to Drive Intervertebral Disc Degeneration.Adv Sci (Weinh)202641917726PubTator, text miningPubMed
A conserved mycobacterial nucleomodulin hijacks the host COMPASS complex to reprogram pro-inflammatory transcription and promote intracellular survival.Elife202641915568PubTator, text miningPubMed
SYT8 Drives Colorectal Cancer Progression and Immune Evasion via the SETD1A-H3K4me3 Axis.Am J Pathol202641881308PubTator, text miningPubMed
The JMJD family histone demethylases: structure, mechanism of action, diseases and therapeutic targets.Mol Biomed202641857315PubTator, text miningPubMed
Dectin-1 epigenetic reprogramming rescues senescent-like Treg function in allergic asthma.Life Sci Alliance202641844277PubTator, text miningPubMed
Set1 promotes Notch-induced transcriptional activation.Cell Mol Life Sci202641843107PubTator, text miningPubMed
RNA polymerase II: the elephant in the room.Trends Genet202641820080PubTator, text miningPubMed
The role of receptor binding and immunity in SARS-CoV-2 fitness landscape: A modeling study.iScience202641809055PubTator, text miningPubMed
FOXA2 as a SETD1A-Regulated Driver of Tamoxifen Resistance in Breast Cancer.Oncol Res202641799508PubTator, text miningPubMed
Unraveling fibrinogen-like protein 1's role in immune regulation.Front Immunol202641789095PubTator, text miningPubMed
METTL3 Methylation Induces Decay of Endogenous Retroelement Transcripts to Promote Tumor Immune Evasion.Cancer Res202641784625PubTator, text miningPubMed
Nuclear and Mitochondrial Epigenetic Mechanisms Underlying Neurodegeneration and Gut-Brain Axis Dysregulation Induced by Micro- and Nanoplastics.Genes (Basel)202641751535PubTator, text miningPubMed

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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