Gene · 976
ADGRE5: adhesion G protein-coupled receptor E5
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ADGRE5: adhesion G protein-coupled receptor E5. Genes, record 976. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/976
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P48960 | Adhesion G protein-coupled receptor E5 | 835 | 9 | Ensembl, GeneID, HGNC |
Source UniProt
Patents51
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 40659 | P48960 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1072 | P48960 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 751 | P48960 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 438 | P48960 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 306 | P48960 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 5412 | P48960 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 306 | P48960 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 5412 | P48960 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 751 | P48960 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1072 | P48960 | Espacenet |
1 to 10 of 51
See all 51 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants590
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ADGRE5 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 3 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 3 | 2025 |
| R01AI040098 | B lymphocyte Migration and Homeostasis | 3 | 2025 |
| R01NS124920 | Developmentally Regulated Enhancers and Chromatin Architecture in Human Neurogenesis | 3 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 2 | 2025 |
| P51OD011104 | Tulane National Primate Research Center | 2 | 2025 |
| R01CA251669 | Adhesion GPCR regulation of acute myeloid leukemia stem cells - Resubmission - 1 | 2 | 2025 |
| UL1TR001445 | Clinical and Translational Science Award | 2 | 2025 |
| ZICBC010947 | Laboratory of Cancer Biology and Genetics Microscopy Core Facility | 2 | 2025 |
1 to 10 of 590Source NIH's project files
See all 590 nih grantsPapers951
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Efferocytosis triggered proteomic reprogramming of macrophages reveals CD97 as a novel apoptotic receptor. | Cell Death Differ | 2026 | 42811049 | PubTator, text mining | PubMed |
| CD97/ADGRE5 in Cancer: Structural Activation, Context-Dependent Signaling, and Therapeutic Targeting. | Cells | 2026 | 42738898 | PubTator, text mining | PubMed |
| CD55 organizes lipid raft-LCK signaling to potentiate NK-cell antitumor immunity. | Cell Res | 2026 | 42693249 | PubTator, text mining | PubMed |
| Multi-Omics Integration Reveals That SN-011 Targets JUNB to Upregulate ADGRE5 and Restore Vascular Endothelial Cell Communication in Ischemic Stroke. | Chem Biol Drug Des | 2026 | 42549987 | PubTator, text mining | PubMed |
| Overexpression of CD97 in intestinal epithelial cells attenuates LPS-induced pro-inflammatory cytokine induction via stabilization of β-catenin early in life. | PLoS One | 2026 | 42531273 | PubTator, text mining | PubMed |
| A spatially organized immune-stromal program drives the fissure-to-fistula continuum in Crohn's disease. | J Crohns Colitis | 2026 | 42522256 | PubTator, text mining | PubMed |
| Immune regulation by CD55 in chronic beryllium disease. | Am J Respir Cell Mol Biol | 2026 | 42089302 | PubTator, text mining | PubMed |
| Advances in the mechanisms of extracellular vesicles and circulating tumor cells in hepatocellular carcinoma metastasis (Review). | Mol Med Rep | 2026 | 41930461 | PubTator, text mining | PubMed |
| Single-cell insights into trophoblast heterogeneity and adaptive dysfunction in selective fetal growth restriction. | Commun Biol | 2026 | 41845016 | PubTator, text mining | PubMed |
| Preclinical advances and mechanistic insights of CAR-T therapy for acute myeloid leukemia: from target iteration to microenvironment regulation. | Ann Med | 2026 | 41800605 | PubTator, text mining | PubMed |
1 to 10 of 951
See all 951 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/976
GET https://conductscience.org/api/genes/v1/976/patents?page=2