Gene · 9775
EIF4A3: eukaryotic translation initiation factor 4A3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. EIF4A3: eukaryotic translation initiation factor 4A3. Genes, record 9775. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9775
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P38919 | Eukaryotic initiation factor 4A-III | 411 | 22 | Ensembl, GeneID, HGNC |
Source UniProt
Patents54
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 19634 | P38919 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 25415 | P38919 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 25415 | P38919 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 19634 | P38919 | Espacenet |
| JP 2025514983 A | 2025-05-13 | 12 | P38919 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 27713 | P38919 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 27713 | P38919 | Espacenet |
| US 11694765 B2 | 2023-07-04 | 144 | P38919 | Espacenet |
| US 11694765 B2 | 2023-07-04 | 250 | P38919 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 27713 | P38919 | Espacenet |
1 to 10 of 54
See all 54 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants818
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | EIF4A3 papers | Newest fiscal year |
|---|---|---|---|
| P20GM121176 | Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2. | 5 | 2025 |
| P30AI027763 | UCSF-Bay Area Center for AIDS Research | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30CA045508 | CSHL Cancer Center Support Grant | 4 | 2025 |
| P01CA125066 | Discovery of Anticancer Agents of Diverse Natural Origin | 3 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| R01GM042699 | Biochemistry of Pre-mRNA Splicing | 3 | 2025 |
1 to 10 of 818Source NIH's project files
See all 818 nih grantsPapers1,749
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
Statement of Retraction: Circ 003390/Eukaryotic translation initiation factor 4A3 promoted cell migration and proliferation in endometrial cancer via vascular endothelial growth factor signaling by miR-195-5p. | Bioengineered | 2026 | 42821798 | PubTator, text mining | PubMed |
| [Inhibition of RBM5 expression by the interaction between hsa_circ_0006200 and EIF4A3 and its impact on cervical cancer progression]. | Zhonghua Fu Chan Ke Za Zhi | 2026 | 42802115 | PubTator, text mining | PubMed |
| EIF4A3-mediated downregulation of circ_0073586 promotes cadmium-induced lung carcinogenesis through SRSF9-triggered GPX4-dependent ferroptosis resistance. | Ecotoxicol Environ Saf | 2026 | 42641444 | PubTator, text mining | PubMed |
| Single-cell transcriptomics reveals a correlation between inflammatory C7 fibroblasts in cervical tumor-adjacent normal tissues and cervical cancer progression. | Front Cell Dev Biol | 2026 | 42638795 | PubTator, text mining | PubMed |
| Assembly of exon junction complexes on spliceosomes begins before spliceosome activation. | Nucleic Acids Res | 2026 | 42635127 | PubTator, text mining | PubMed |
| Transcriptomic landscape of human circular RNAs: unveiling molecular mechanisms in high-altitude adaptation. | Front Genet | 2026 | 42634741 | PubTator, text mining | PubMed |
| Pervasive noise in human pre-mRNA splice site selection. | Mol Cell | 2026 | 42607686 | PubTator, text mining | PubMed |
| Pathophysiological and translational implications of the dysregulation of molecular machineries controlling RNA metabolism in thyrotropinomas. | iScience | 2026 | 42602702 | PubTator, text mining | PubMed |
| Lactylation of EIF4A3 mediates sustained circPTK2 biogenesis to drive prostate cancer metastasis. | Cancer Lett | 2026 | 42595075 | PubTator, text mining | PubMed |
| EIF4A3-dependent nonsense-mediated decay buffers AML1-ETO9a dosage and modulates outcome in t(8;21) acute myeloid leukemia. | Leukemia | 2026 | 42448936 | PubTator, text mining | PubMed |
1 to 10 of 1,749
See all 1,749 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/9775
GET https://conductscience.org/api/genes/v1/9775/patents?page=2