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Gene · 9782

MATR3: matrin 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MATR3: matrin 3. Genes, record 9782. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9782

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Gene

Symbol
MATR3
HGNC
Name
matrin 3
HGNC
NCBI Gene ID
9782
NCBI Gene
HGNC ID
HGNC:6912
HGNC
Ensembl
ENSG00000015479
NCBI Gene
Aliases
ALS21, KIAA0723, MGC9105, MPD2, VCPDM
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P43243Matrin-38470Ensembl, GeneID, HGNC

Source UniProt

Patents83

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1452716P43243Espacenet
JP 2026004568 A2026-01-1452717P43243Espacenet
JP 2026004568 A2026-01-1452727P43243Espacenet
EP 4650780 A22025-11-197855P43243Espacenet
EP 4641201 A22025-10-297950P43243Espacenet
JP 2025147176 A2025-10-068367P43243Espacenet
JP 2025147176 A2025-10-068369P43243Espacenet
JP 2025147176 A2025-10-068371P43243Espacenet
JP 2025147176 A2025-10-068374P43243Espacenet
JP 2025147176 A2025-10-0615261P43243Espacenet

1 to 10 of 83

See all 83 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,098

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMATR3 papersNewest fiscal year
R01NS097542RNA decay in amyotrophic lateral sclerosis and frontotemporal lobar degeneration62025
ZIAAG000933Genetic etiology of Amyotrophic Lateral Sclerosis62025
P30CA008748Cancer Center Support Grant52025
P30CA077598Cancer Center Support Grant42025
R01DK018477Enhancer Connectomes in Regulation of Gene Expression42025
U54NS092091Clinical Research in ALS and Related Disorders for Therapeutic Development (CReATe)42025
ZIACP010121Molecular Epidemiology Studies of Occupational and Environmental Exposures42025
P30CA016086Cancer Center Support Grant32025
P50CA217694SPORE in Soft Tissue Sarcoma32025
R01AG031867Protein aggregation in inclusion body and myofibrillar myopathies32025

1 to 10 of 1,098Source NIH's project files

See all 1,098 nih grants

Papers1,420

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
MATR3 is essential for oocyte growth and maturation quality through a dual molecular mechanism.Elife202642765984PubTator, text miningPubMed
MATR3 promotes proliferation and invasion of colon adenocarcinoma cells: bulk, single-cell transcriptomic analysis and experimental validation.Transl Oncol202642743658PubTator, text miningPubMed
Pervasive noise in human pre-mRNA splice site selection.Mol Cell202642607686PubTator, text miningPubMed
The EV-A71 RNA-binding protein Matrin 3 facilitates viral replication by stabilizing viral RNA via ZDHHC20-mediated palmitoylation.Proc Natl Acad Sci U S A202642546198PubTator, text miningPubMed
A 57-Year-Old Male With Behavioral Variant Frontotemporal Dementia and MATR3 and NOS3 Mutations.Ann Clin Transl Neurol202642374607PubTator, text miningPubMed
Modification of internal RNA domains from the long non-coding RNA XIST refines roles in silencing and heterochromatin recruitment.Hum Mol Genet202641926242PubTator, text miningPubMed
RNA binding as an emerging regulatory dimension in the type I IFN response.Cell Rep202641904951PubTator, text miningPubMed
A quantitative cell-based reporter links TDP-43 aggregation and dysfunction to define pathogenic mechanisms.PLoS Biol202641875078PubTator, text miningPubMed
A multigene model for response stratification to neoadjuvant chemotherapy in triple negative breast cancer.Breast202641863200PubTator, text miningPubMed
MATR3 regulates METTL3-Mediated m6A modification of MSI2 mRNA to activate the Wnt/β-Catenin pathway, exacerbating myocardial fibrosis and atrial fibrillation.J Bioenerg Biomembr202641849072PubTator, text miningPubMed

1 to 10 of 1,420

See all 1,420 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9782

GET https://conductscience.org/api/genes/v1/9782/patents?page=2