Gene · 9821
RB1CC1: RB1 inducible coiled-coil 1
12 sourcesgene-search-2026-11-11-0.2.0
Download JSON
Cite this record
ConductScience Library. RB1CC1: RB1 inducible coiled-coil 1. Genes, record 9821. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9821
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q8TDY2 | RB1-inducible coiled-coil protein 1 | 1,594 | 18 | Ensembl, GeneID, HGNC |
Source UniProt
Patents19
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 62 | Q8TDY2 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 46 | Q8TDY2 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 46 | Q8TDY2 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 62 | Q8TDY2 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 8137 | Q8TDY2 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 71992 | Q8TDY2 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 174963 | Q8TDY2 | Espacenet |
| US 10501513 B2 | 2019-12-10 | 8137 | Q8TDY2 | Espacenet |
| JP 2017197545 A | 2017-11-02 | 32838 | Q8TDY2 | Espacenet |
| US 9587003 B2 | 2017-03-07 | 8137 | Q8TDY2 | Espacenet |
1 to 10 of 19
See all 19 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,585
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | RB1CC1 papers | Newest fiscal year |
|---|---|---|---|
| R01CA126792 | Autophagy and Pro-metastatic Differentiation | 13 | 2025 |
| P20GM121176 | Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2. | 11 | 2025 |
| R01HL073394 | Mechanisms of progression of vascular malformation to lymphangiosarcoma | 11 | 2025 |
| R35GM131919 | The mechanism and regulation of autophagy | 10 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 9 | 2025 |
| R37AI042999 | Pattern Recognition Receptors and Autophagy in Mtb Control in AIDS | 9 | 2025 |
| P20GM113132 | The Institute for Biomolecular Targeting | 8 | 2025 |
| P30CA023108 | Cancer Center Support Grant | 8 | 2025 |
| P30DK043351 | Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital | 8 | 2025 |
| P01CA120964 | Molecular Pathogenesis of the Hamartoma Syndromes | 7 | 2025 |
1 to 10 of 1,585Source NIH's project files
See all 1,585 nih grantsPapers2,963
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Analysis of Rare Coding Variation Identifies New Genetic Contributors to Schizophrenia. | bioRxiv | 2026 | 42818077 | PubTator, text mining | PubMed |
| Unc-51 like kinase 3 (ULK3) contributes to autophagy and cell survival in multiple myeloma. | Nat Commun | 2026 | 42778564 | PubTator, text mining | PubMed |
| Reconstitution of multistep recruitment of ULK1 to membranes in autophagy. | Sci Adv | 2026 | 42696573 | PubTator, text mining | PubMed |
| Dentate gyrus immaturity and region-specific synaptic and autophagy alterations across hippocampal subfields in schizophrenia. | Schizophr Res | 2026 | 42603365 | PubTator, text mining | PubMed |
| Clearance and secretion of α-synuclein by RTN3L-mediated endoplasmic reticulum autophagy. | Mol Biol Cell | 2026 | 42455619 | PubTator, text mining | PubMed |
| Antibody-dependent xenophagy targets viruses and bacteria for destruction. | Autophagy | 2026 | 42418235 | PubTator, text mining | PubMed |
| Screening-based repurposing identifies potassium dehydroandrographolide succinate (KDAS) as a selective suppressor of TNF-α-induced caspase-8-dependent apoptosis in colonic epithelial cells. | Sci Rep | 2026 | 42265132 | PubTator, text mining | PubMed |
| LY86-AS1 predicts poor prognosis and inhibits progression in non-small cell lung cancer by targeting the miR-132-3p/RB1CC1 axis. | World J Surg Oncol | 2026 | 42260571 | PubTator, text mining | PubMed |
| Exploiting autophagy-targeting natural compounds for potential antimicrobial actions. | Autophagy | 2026 | 42047332 | PubTator, text mining | PubMed |
| Golgi-derived phosphatidylinositol 4-phosphate is crucial for organization of the preautophagosomal structure. | J Biol Chem | 2026 | 41966270 | PubTator, text mining | PubMed |
1 to 10 of 2,963
See all 2,963 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/9821
GET https://conductscience.org/api/genes/v1/9821/patents