Gene · 9846
GAB2: GRB2 associated binding protein 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GAB2: GRB2 associated binding protein 2. Genes, record 9846. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9846
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9UQC2 | GRB2-associated-binding protein 2 | 676 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents40
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 48234 | Q9UQC2 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 7977 | Q9UQC2 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 7977 | Q9UQC2 | Espacenet |
| JP 2025062601 A | 2025-04-14 | 5 | Q9UQC2 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 28669 | Q9UQC2 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 28669 | Q9UQC2 | Espacenet |
| US 12006548 B2 | 2024-06-11 | 456 | Q9UQC2 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 28669 | Q9UQC2 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 36299 | Q9UQC2 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 139270 | Q9UQC2 | Espacenet |
1 to 10 of 40
See all 40 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,515
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GAB2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 20 | 2025 |
| U24AG021886 | National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD) | 17 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 10 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 7 | 2025 |
| P01CA120964 | Molecular Pathogenesis of the Hamartoma Syndromes | 4 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 4 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 4 | 2025 |
| P30CA091842 | Cancer Center Support Grant | 4 | 2025 |
| P01CA108671 | Myeloproliferative Neoplasms-Research Consortium | 3 | 2025 |
| P30CA006516 | Dana-Farber/Harvard Cancer Center | 3 | 2025 |
1 to 10 of 1,515Source NIH's project files
See all 1,515 nih grantsPapers1,533
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Disseminated Xanthogranuloma Harboring a GAB2::BRAF Fusion and MITF Pathogenic Variant Successfully Treated With Cobimetinib: A Rare Case Report. | J Cutan Pathol | 2026 | 42813601 | PubTator, text mining | PubMed |
| Micellar curcumol reprograms tumor-associated macrophages and reverses PARP inhibitor resistance in recurrent ovarian cancer. | Phytomedicine | 2026 | 42365697 | PubTator, text mining | PubMed |
| Genetic Analysis of Acral Melanomas From Southern African Patients. | Pigment Cell Melanoma Res | 2026 | 42290081 | PubTator, text mining | PubMed |
| Integrative Genomic and Epigenomic Dissection of Facial Morphology in Chinese Populations. | Genomics Proteomics Bioinformatics | 2026 | 42266000 | PubTator, text mining | PubMed |
| Genomic Survey of Selection Footprints in Three Buffalo Breeds from Eastern Europe. | Animals (Basel) | 2026 | 42193820 | PubTator, text mining | PubMed |
| A risk scoring model for lung squamous cell carcinoma based on epithelial-mesenchymal transition-related genes: an integrative analysis of prognosis and immune infiltration characteristics. | PeerJ | 2026 | 42089102 | PubTator, text mining | PubMed |
| GAB3 suppresses lung adenocarcinoma progression by inhibiting the MAPK signaling and potentiating CD8+ T cell immunity. | Cancer Lett | 2026 | 42031161 | PubTator, text mining | PubMed |
| Ginsenoside-Rh2 inhibits U251 glioma cell migration and invasion via the Gab2/Akt2 pathway. | Front Oncol | 2026 | 41994641 | PubTator, text mining | PubMed |
| Antibody screening for tumor and immune hotspot targets: The frontier of new methods and technologies. | J Pharm Anal | 2026 | 41798069 | PubTator, text mining | PubMed |
| Physalin A Suppresses Human Oral Squamous Carcinoma Cell Migration and Invasion Through Inhibiting Grb2/Ras and MMP/uPA Signaling Pathways. | In Vivo | 2026 | 41760308 | PubTator, text mining | PubMed |
1 to 10 of 1,533
See all 1,533 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/9846
GET https://conductscience.org/api/genes/v1/9846/patents?page=2