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Gene · 9846

GAB2: GRB2 associated binding protein 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GAB2: GRB2 associated binding protein 2. Genes, record 9846. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9846

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Gene

Symbol
GAB2
HGNC
Name
GRB2 associated binding protein 2
HGNC
NCBI Gene ID
9846
NCBI Gene
HGNC ID
HGNC:14458
HGNC
Ensembl
ENSG00000033327
NCBI Gene
Aliases
KIAA0571
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UQC2GRB2-associated-binding protein 267610Ensembl, GeneID, HGNC

Source UniProt

Patents40

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1448234Q9UQC2Espacenet
EP 4650780 A22025-11-197977Q9UQC2Espacenet
JP 2025517970 A2025-06-127977Q9UQC2Espacenet
JP 2025062601 A2025-04-145Q9UQC2Espacenet
JP 2025032204 A2025-03-1128669Q9UQC2Espacenet
EP 4461818 A22024-11-1328669Q9UQC2Espacenet
US 12006548 B22024-06-11456Q9UQC2Espacenet
JP 2023058610 A2023-04-2528669Q9UQC2Espacenet
US 11446398 B22022-09-2036299Q9UQC2Espacenet
JP 2022524081 A2022-04-27139270Q9UQC2Espacenet

1 to 10 of 40

See all 40 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,515

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGAB2 papersNewest fiscal year
P30CA016672Cancer Center Support Grant202025
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)172025
P30CA008748Cancer Center Support Grant102025
P30CA076292Moffitt Cancer Center Support Grant72025
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes42025
P30CA016056Roswell Park Cancer Center Support Grant42025
P30CA068485Cancer Center Support Grant42025
P30CA091842Cancer Center Support Grant42025
P01CA108671Myeloproliferative Neoplasms-Research Consortium32025
P30CA006516Dana-Farber/Harvard Cancer Center32025

1 to 10 of 1,515Source NIH's project files

See all 1,515 nih grants

Papers1,533

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Disseminated Xanthogranuloma Harboring a GAB2::BRAF Fusion and MITF Pathogenic Variant Successfully Treated With Cobimetinib: A Rare Case Report.J Cutan Pathol202642813601PubTator, text miningPubMed
Micellar curcumol reprograms tumor-associated macrophages and reverses PARP inhibitor resistance in recurrent ovarian cancer.Phytomedicine202642365697PubTator, text miningPubMed
Genetic Analysis of Acral Melanomas From Southern African Patients.Pigment Cell Melanoma Res202642290081PubTator, text miningPubMed
Integrative Genomic and Epigenomic Dissection of Facial Morphology in Chinese Populations.Genomics Proteomics Bioinformatics202642266000PubTator, text miningPubMed
Genomic Survey of Selection Footprints in Three Buffalo Breeds from Eastern Europe.Animals (Basel)202642193820PubTator, text miningPubMed
A risk scoring model for lung squamous cell carcinoma based on epithelial-mesenchymal transition-related genes: an integrative analysis of prognosis and immune infiltration characteristics.PeerJ202642089102PubTator, text miningPubMed
GAB3 suppresses lung adenocarcinoma progression by inhibiting the MAPK signaling and potentiating CD8+ T cell immunity.Cancer Lett202642031161PubTator, text miningPubMed
Ginsenoside-Rh2 inhibits U251 glioma cell migration and invasion via the Gab2/Akt2 pathway.Front Oncol202641994641PubTator, text miningPubMed
Antibody screening for tumor and immune hotspot targets: The frontier of new methods and technologies.J Pharm Anal202641798069PubTator, text miningPubMed
Physalin A Suppresses Human Oral Squamous Carcinoma Cell Migration and Invasion Through Inhibiting Grb2/Ras and MMP/uPA Signaling Pathways.In Vivo202641760308PubTator, text miningPubMed

1 to 10 of 1,533

See all 1,533 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9846

GET https://conductscience.org/api/genes/v1/9846/patents?page=2